Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jorg, Tost"'
Autor:
Nora Fernandez-Jimenez, Ruby Fore, Ariadna Cilleros-Portet, Johanna Lepeule, Patrice Perron, Tuomas Kvist, Fu-Ying Tian, Corina Lesseur, Alexandra M. Binder, Manuel Lozano, Jordi Martorell-Marugán, Yuk J. Loke, Kelly M. Bakulski, Yihui Zhu, Anne Forhan, Sara Sammallahti, Todd M. Everson, Jia Chen, Karin B. Michels, Thalia Belmonte, Pedro Carmona-Sáez, Jane Halliday, M. Daniele Fallin, Janine M. LaSalle, Jorg Tost, Darina Czamara, Mariana F. Fernández, Antonio Gómez-Martín, Jeffrey M. Craig, Beatriz Gonzalez-Alzaga, Rebecca J. Schmidt, John F. Dou, Evelyne Muggli, Marina Lacasaña, Martine Vrijheid, Carmen J. Marsit, Margaret R. Karagas, Katri Räikkönen, Luigi Bouchard, Barbara Heude, Loreto Santa-Marina, Mariona Bustamante, Marie-France Hivert, Jose Ramon Bilbao
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
A meta-analysis of pre-pregnancy maternal body mass index (ppBMI) and placental DNA methylation from 2631 mother-child pairs identifies 27 CpG sites associated with ppBMI, providing insight into how maternal obesity could be associated with metabolic
Externí odkaz:
https://doaj.org/article/25f6e68216ef415aa23b5efa7f8762a9
Autor:
Tejaswi V. Badam, Sandra Hellberg, Ratnesh B. Mehta, Jeannette Lechner-Scott, Rodney A. Lea, Jorg Tost, Xavier Mariette, Judit Svensson-Arvelund, Colm E. Nestor, Mikael Benson, Göran Berg, Maria C. Jenmalm, Mika Gustafsson, Jan Ernerudh
Publikováno v:
Epigenetics, Vol 17, Iss 9, Pp 1040-1055 (2022)
Epigenetics may play a central, yet unexplored, role in the profound changes that the maternal immune system undergoes during pregnancy and could be involved in the pregnancy-induced modulation of several autoimmune diseases. We investigated changes
Externí odkaz:
https://doaj.org/article/82fde3e3be1f4925b203e0997ce02cf5
Autor:
Delphine Fradin, Jorg Tost, Florence Busato, Clémence Mille, Fanny Lachaux, Jean-François Deleuze, Gisèle Apter, Alexandra Benachi
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Pregnancy is a state of multiple physiological adaptations. Since methylation of DNA is an epigenetic mechanism that regulates gene expression and contributes to adaptive phenotypic variations, we investigated methylation changes in maternal blood of
Externí odkaz:
https://doaj.org/article/7eb50a585b2f4e1a955ea7a175e61f5d
Autor:
Rebekka M. Koeck, Florence Busato, Jorg Tost, Dimitri Consten, Jannie van Echten-Arends, Sebastiaan Mastenbroek, Yvonne Wurth, Sylvie Remy, Sabine Langie, Tim S. Nawrot, Michelle Plusquin, Rossella Alfano, Esmée M. Bijnens, Marij Gielen, Ron van Golde, John C. M. Dumoulin, Han Brunner, Aafke P. A. van Montfoort, Masoud Zamani Esteki
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-11 (2022)
Abstract A growing number of children born are conceived through in vitro fertilisation (IVF), which has been linked to an increased risk of adverse perinatal outcomes, as well as altered growth profiles and cardiometabolic differences in the resulta
Externí odkaz:
https://doaj.org/article/0944abd68faf439091e0b81737fc154a
Autor:
Todd M. Everson, Marta Vives-Usano, Emie Seyve, Andres Cardenas, Marina Lacasaña, Jeffrey M. Craig, Corina Lesseur, Emily R. Baker, Nora Fernandez-Jimenez, Barbara Heude, Patrice Perron, Beatriz Gónzalez-Alzaga, Jane Halliday, Maya A. Deyssenroth, Margaret R. Karagas, Carmen Íñiguez, Luigi Bouchard, Pedro Carmona-Sáez, Yuk J. Loke, Ke Hao, Thalia Belmonte, Marie A. Charles, Jordi Martorell-Marugán, Evelyne Muggli, Jia Chen, Mariana F. Fernández, Jorg Tost, Antonio Gómez-Martín, Stephanie J. London, Jordi Sunyer, Carmen J. Marsit, Johanna Lepeule, Marie-France Hivert, Mariona Bustamante
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Maternal smoking during pregnancy contributes to poor birth outcomes. Here the authors perform a meta-analysis of the associations between maternal smoking during pregnancy and placental DNA methylation and identify links between these and poor birth
Externí odkaz:
https://doaj.org/article/dc8ffa9450d144648dc5bb3dac95b454
Autor:
Arnaud Carrier, Cécile Desjobert, Loic Ponger, Laurence Lamant, Matias Bustos, Jorge Torres-Ferreira, Rui Henrique, Carmen Jeronimo, Luisa Lanfrancone, Audrey Delmas, Gilles Favre, Antoine Daunay, Florence Busato, Dave SB Hoon, Jorg Tost, Chantal Etievant, Joëlle Riond, Paola B Arimondo
Publikováno v:
eLife, Vol 11 (2022)
Aberrant DNA methylation is a well-known feature of tumours and has been associated with metastatic melanoma. However, since melanoma cells are highly heterogeneous, it has been challenging to use affected genes to predict tumour aggressiveness, meta
Externí odkaz:
https://doaj.org/article/178e2f9d24ea43bdaf03054ad233b3ef
Autor:
Sophie Rousseaux, Emie Seyve, Florent Chuffart, Ekaterina Bourova-Flin, Meriem Benmerad, Marie-Aline Charles, Anne Forhan, Barbara Heude, Valérie Siroux, Remy Slama, Jorg Tost, Daniel Vaiman, Saadi Khochbin, Johanna Lepeule, the EDEN Mother-Child Cohort Study Group
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-20 (2020)
Abstract Background Although exposure to cigarette smoking during pregnancy has been associated with alterations of DNA methylation in the cord blood or placental cells, whether such exposure before pregnancy could induce epigenetic alterations in th
Externí odkaz:
https://doaj.org/article/6e72306cf67546a48f95c80f1bffc6e6
Autor:
Rasmus Rydbirk, Jonas Folke, Florence Busato, Elodie Roché, Alisha Shahzad Chauhan, Annemette Løkkegaard, Anne-Mette Hejl, Matthias Bode, Morten Blaabjerg, Mette Møller, Erik Hvid Danielsen, Tomasz Brudek, Bente Pakkenberg, Jorg Tost, Susana Aznar
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-14 (2020)
Abstract Multiple system atrophy (MSA) is a rare disease with a fatal outcome. To date, little is known about the molecular processes underlying disease development. Its clinical overlap with related neurodegenerative movement disorders underlines th
Externí odkaz:
https://doaj.org/article/b14bb7e1bdfb44779cb1ebeea84015cd
Autor:
Aurélien Ducat, Betty Couderc, Anthony Bouter, Louise Biquard, Rajaa Aouache, Bruno Passet, Ludivine Doridot, Marie-Benoîte Cohen, Pascale Ribaux, Clara Apicella, Irène Gaillard, Sophia Palfray, Yulian Chen, Alexandra Vargas, Amélie Julé, Léo Frelin, Julie Cocquet, Camino Ruano San Martin, Sébastien Jacques, Florence Busato, Jorg Tost, Céline Méhats, Paul Laissue, Jean-Luc Vilotte, Francisco Miralles, Daniel Vaiman
Publikováno v:
iScience, Vol 23, Iss 5, Pp - (2020)
Summary: STOX1 is a transcription factor involved in preeclampsia and Alzheimer disease. We show that the knock-down of the gene induces rather mild effect on gene expression in trophoblast cell lines (BeWo). We identified binding sites of STOX1 shar
Externí odkaz:
https://doaj.org/article/b54fcc60ee1d4939917d4e09e86f70c3
Autor:
Gabrielle Perron, Pouria Jandaghi, Shraddha Solanki, Maryam Safisamghabadi, Cristina Storoz, Mehran Karimzadeh, Andreas I. Papadakis, Madeleine Arseneault, Ghislaine Scelo, Rosamonde E. Banks, Jorg Tost, Mark Lathrop, Simon Tanguay, Alvis Brazma, Sidong Huang, Fadi Brimo, Hamed S. Najafabadi, Yasser Riazalhosseini
Publikováno v:
Cell Reports, Vol 23, Iss 6, Pp 1639-1650 (2018)
Summary: Widespread remodeling of the transcriptome is a signature of cancer; however, little is known about the post-transcriptional regulatory factors, including RNA-binding proteins (RBPs) that regulate mRNA stability, and the extent to which RBPs
Externí odkaz:
https://doaj.org/article/2c6169ff271e4777ae7795ebf02b21f3