Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jordyn J. VanPortfliet"'
Autor:
Yuanjiu Lei, Jordyn J. VanPortfliet, Yi-Fan Chen, Joshua D. Bryant, Ying Li, Danielle Fails, Sylvia Torres-Odio, Katherine B. Ragan, Jingti Deng, Armaan Mohan, Bing Wang, Olivia N. Brahms, Shawn D. Yates, Michael Spencer, Carl W. Tong, Marcus W. Bosenberg, Laura Ciaccia West, Gerald S. Shadel, Timothy E. Shutt, Jason W. Upton, Pingwei Li, A. Phillip West
SUMMARYMitochondrial DNA (mtDNA) is a potent agonist of the innate immune system; however, the exact immunostimulatory features of mtDNA and the kinetics of mtDNA detection by cytosolic nucleic acid sensors remain poorly defined. Here, we show that m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40762d17c3bc167f537854a7fe731c1b
https://doi.org/10.1101/2022.05.30.493783
https://doi.org/10.1101/2022.05.30.493783
Autor:
Chi G. Weindel, Eduardo L. Martinez, Xiao Zhao, Cory J. Mabry, Samantha L. Bell, Krystal J. Vail, Aja K. Coleman, Jordyn J. VanPortfliet, Baoyu Zhao, Allison R. Wagner, Sikandar Azam, Haley M. Scott, Pingwei Li, A. Phillip West, Jason Karpac, Kristin L. Patrick, Robert O. Watson
Publikováno v:
Cell. 185:3214-3231.e23
Although mutations in mitochondrial-associated genes are linked to inflammation and susceptibility to infection, their mechanistic contributions to immune outcomes remain ill-defined. We discovered that the disease-associated gain-of-function allele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa1c9c6f5595b9edba7b01127d4e15a6
https://doi.org/10.1016/j.cell.2022.06.038
https://doi.org/10.1016/j.cell.2022.06.038
Autor:
Chi Gidley Weindel, Xiao Zhao, Eduardo Martinez, Samantha L. Bell, Krystal J. Vail, Aja K. Coleman, Jordyn J. VanPortfliet, Cory J. Mabry, Pingwei Li, A. Phillip West, Jason Karpac, Kristin L. Patrick, Robert O. Watson
Publikováno v:
The Journal of Immunology. 208:52.06-52.06
Human genetic variants associated with mitochondrial dysfunction have been linked to chronic inflammatory diseases as well as susceptibility to infection. However, the mechanistic impact that these variants have on the immune system is poorly underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0be09cf2153099729e7d2fbd26eea93
https://doi.org/10.4049/jimmunol.208.supp.52.06
https://doi.org/10.4049/jimmunol.208.supp.52.06
Autor:
Olenic S; Department of Biochemistry and Molecular Biology, Michigan State Universitygrid.17088.36, East Lansing, Michigan, USA., Buchanan F; Department of Biochemistry and Molecular Biology, Michigan State Universitygrid.17088.36, East Lansing, Michigan, USA., VanPortfliet J; Department of Biochemistry and Molecular Biology, Michigan State Universitygrid.17088.36, East Lansing, Michigan, USA., Parrell D; Department of Biochemistry and Molecular Biology, Michigan State Universitygrid.17088.36, East Lansing, Michigan, USA., Kroos L; Department of Biochemistry and Molecular Biology, Michigan State Universitygrid.17088.36, East Lansing, Michigan, USA.
Publikováno v:
Journal of bacteriology [J Bacteriol] 2022 Mar 15; Vol. 204 (3), pp. e0038621. Date of Electronic Publication: 2022 Jan 10.