Výsledky vyhledávání - "Jordi Malapeira"

The impact of chromatin dynamics on plant light responses and circadian clock function

Autor: Paloma Mas, Jordi Malapeira, Fredy Barneche

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

Research on the functional properties of nucleosome structure and composition dynamics has revealed that chromatin-level regulation is an essential component of light signalling and clock function in plants, two processes that rely extensively on tra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b9b510f2bb530ccad0e12f97f77b394
https://doi.org/10.1093/jxb/eru011

Zobrazit plný text záznamu

iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain shedding

Autor: Tak W. Mak, Xue Li, David R. McIlwain, Sadaf Amin, Priya D. Issuree, Philipp A. Lang, Jordi Malapeira, Thorsten Maretzky, Carl P. Blobel

Publikováno v: Proc Natl Acad Sci U S A

Protein ectodomain shedding by ADAM17 (a disintegrin and metalloprotease 17), a principal regulator of EGF-receptor signaling and TNFα release, is rapidly and posttranslationally activated by a variety of signaling pathways, and yet little is known

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaf72a6fac5000041d7e132922e7f288
https://doi.org/10.1073/pnas.1302553110

Zobrazit plný text záznamu

Ordered changes in histone modifications at the core of the Arabidopsis circadian clock

Autor: Lucie Crhak Khaitova, Paloma Mas, Jordi Malapeira

Publikováno v: Proceedings of the National Academy of Sciences. 109:21540-21545

Circadian clock function in Arabidopsis thaliana relies on a complex network of reciprocal regulations among oscillator components. Here, we demonstrate that chromatin remodeling is a prevalent regulatory mechanism at the core of the clock. The peak-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0da8a97da9e915a303e6f2f7c10b4a1a
https://doi.org/10.1073/pnas.1217022110

Zobrazit plný text záznamu

SFRPs act as negative modulators of ADAM10 to regulate retinal neurogenesis

Autor: Inmaculada Crespo, Pilar Esteve, Joaquín Arribas, Sara González-García, María L. Toribio, Jordi Malapeira, Paola Bovolenta, Marcos J. Cardozo, Isabel Guerrero, Carmen Ibañez, Akihiko Shimono, Séverine Marcos, África Sandonís

Publikováno v: Nature Neuroscience. 14:562-569

Secreted frizzled-related proteins (SFRPs) are putative Wnt antagonists. Here, Esteve et al. show that SFRPs during eye development can also serve as inhibitors of Notch signaling by acting on ADAM10 metalloprotease activity. It is well established t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dfce3dc28b4c2d7b1d7edd1853089f1
https://doi.org/10.1038/nn.2794

Zobrazit plný text záznamu

Metastasis-associated C4.4A, a GPI-anchored protein cleaved by ADAM10 and ADAM17

Autor: Marcia L. Moss, Joaquín Arribas, Cary Esselens, Nuria Colomé, Francesc Canals, Jordi Malapeira

Publikováno v: bchm. 389:1075-1084

Metalloproteases play a complex role in tumor progression. While the activity of some ADAM, ADAMTS and matrix metalloproteases (MMPs) seems to be protumorigenic, the activity of others seems to prevent tumor progression. The identification of the arr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f17f8a008b898ed0b948e777e4472b8b
https://doi.org/10.1515/bc.2008.121

Zobrazit plný text záznamu

ChIP-seq analysis of histone modifications at the core of the Arabidopsis circadian clock

Autor: Jordi, Malapeira, Paloma, Mas

Publikováno v: Methods in molecular biology (Clifton, N.J.). 1158

Over the past years, chromatin modification has emerged as a key regulator of gene expression. A very useful method for chromatin analysis is chromatin immunoprecipitation (ChIP), which allows the quantification and localization of specific histone m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4b3f400be0fd6ef6df5871e35eccfdfa
https://pubmed.ncbi.nlm.nih.gov/24792044

Zobrazit plný text záznamu

ChIP-seq analysis of histone modifications at the core of the Arabidopsis circadian clock

Autor: Paloma Mas, Jordi Malapeira

Publikováno v: Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Methods in Molecular Biology ISBN: 9781493906994

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bb5b468cfd89780c54e1b6cd7046151

Zobrazit plný text záznamu

A chromatin-dependent mechanism regulates gene expression at the core of the Arabidopsis circadian clock

Autor: Paloma Mas, Jordi Malapeira

Publikováno v: Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Digital.CSIC. Repositorio Institucional del CSIC
instname

The mechanisms of circadian clock function in Arabidopsis rely on the complex relationships among core clock components. The current model of the Arabidopsis oscillator comprises a myriad of repressors but the mechanisms responsible for activation re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab8d7f633e520ce85dd41f0b811f8fdd

Zobrazit plný text záznamu

ADAM17 (TACE) regulates TGFβ signaling through the cleavage of vasorin

Autor: Joan Josep Bech-Serra, Joaquín Arribas, Jordi Malapeira, Francesc Canals, Carl Esselens

Publikováno v: Oncogene. 30(16)

The activity of a variety of extracellular signaling factors is tightly regulated by proteins containing A Disintegrin And a Metalloprotease domain (ADAM) metalloproteases through limited proteolysis. Thus, the identification of ADAM substrates may u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a385f20deffe4256a101bc2c94468fb
https://pubmed.ncbi.nlm.nih.gov/21170088

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání