Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Jordi L. Tremoleda"'
Publikováno v:
Cells, Vol 13, Iss 19, p 1612 (2024)
Traumatic brain injury (TBI) can cause major disability and increases the risk of neurodegeneration. Post-TBI, there is infiltration of peripheral myeloid and lymphoid cells; there is limited information on the peripheral immune response post-TBI in
Externí odkaz:
https://doaj.org/article/19479738295c43ad8b21879ba2ca2516
Autor:
Cristina Perez-Ternero, Patrick N. Pallier, Jordi L. Tremoleda, Alessio Delogu, Cathy Fernandes, Adina T. Michael-Titus, Adrian J. Hobbs
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
C-type natriuretic peptide (CNP) is highly expressed in the central nervous system (CNS) and key to neuronal development; however, a broader role for CNP in the CNS remains unclear. To address this deficit, we investigated behavioral, sensory and mot
Externí odkaz:
https://doaj.org/article/ae2a5b54964b46a396f1498c2efef783
Autor:
Lucas Teoh, Achintha Avin Ihalage, Srooley Harp, Zahra F. Al-Khateeb, Adina T. Michael-Titus, Jordi L. Tremoleda, Yang Hao
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
The early detection of traumatic brain injuries can directly impact the prognosis and survival of patients. Preceding attempts to automate the detection and the assessment of the severity of traumatic brain injury continue to be based on clinical dia
Externí odkaz:
https://doaj.org/article/d0e86c6ab369421a83cebc52d298e027
Autor:
Louise M. Topping, Bethan L. Thomas, Hefin I. Rhys, Jordi L. Tremoleda, Martyn Foster, Michael Seed, Mathieu-Benoit Voisin, Chiara Vinci, Hannah L. Law, Mauro Perretti, Lucy V. Norling, Helena S. Azevedo, Ahuva Nissim
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The targeted delivery of therapies to diseased tissues offers a safe opportunity to achieve optimal efficacy while limiting systemic exposure. These considerations apply to many disease indications but are especially relevant for rheumatoid arthritis
Externí odkaz:
https://doaj.org/article/244ef4b838bc415988e77e115668a300
Autor:
Johanna Wall, Sriveena Naganathar, Banjerd Praditsuktavorn, Oscar F. Bugg, Simon McArthur, Christoph Thiemermann, Jordi L. Tremoleda, Karim Brohi
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Cardiac dysfunction (CD) importantly contributes to mortality in trauma patients, who survive their initial injuries following successful hemostatic resuscitation. This poor outcome has been correlated with elevated biomarkers of myocardial injury, b
Externí odkaz:
https://doaj.org/article/6646c05adb08403bbee3e896866078d6
Autor:
Ryan M. Pedrigi, Vikram V. Mehta, Sandra M. Bovens, Zahra Mohri, Christian Bo Poulsen, Willy Gsell, Jordi L. Tremoleda, Leila Towhidi, Ranil de Silva, Enrico Petretto, Rob Krams
Publikováno v:
Royal Society Open Science, Vol 3, Iss 10 (2016)
The precise flow characteristics that promote different atherosclerotic plaque types remain unclear. We previously developed a blood flow-modifying cuff for ApoE−/− mice that induces the development of advanced plaques with vulnerable and stable
Externí odkaz:
https://doaj.org/article/76fe35acac5d4fd48f6f80f7901a76a6
Autor:
Jordi L. Tremoleda
Publikováno v:
Revista de Bioética y Derecho, Vol 0, Iss 24, Pp 61-72 (2012)
El 20 de Octubre del 2010 se publico la nueva Directiva Europea 2010/63/EU sobre la protección de los animales utilizados en procedimientos científicos. Dicha publicación en el Diario Oficial de la Unión Europea supone el inicio de su tramitació
Externí odkaz:
https://doaj.org/article/2ae45b46b31842538fcb4d19304eaeb7
Autor:
Simon Cuhlmann, Willy Gsell, Kim Van der Heiden, Josef Habib, Jordi L. Tremoleda, Magdy Khalil, Federico Turkheimer, Merlijn J. Meens, Brenda R. Kwak, Joseph Bird, Anthony P. Davenport, John Clark, Dorian Haskard, Rob Krams, Hazel Jones, Paul C. Evans
Publikováno v:
Molecular Imaging, Vol 13 (2014)
Noninvasive imaging methods are required to monitor the inflammatory content of atherosclerotic plaques. FEDAA1106 (N-(5-fluoro- 2-phenoxyphenyl)- N -(2-(2-fluoroethoxy)-5-methoxybenzyl) acetamide) is a selective ligand for TSPO-18kDa (also known as
Externí odkaz:
https://doaj.org/article/9af240ddb9254772a44d051e519cd85a
Autor:
Jordi L. Tremoleda
Publikováno v:
Frontiers for Young Minds. 10
Even when no other alternatives are available for scientific experiments, the use of research animals is still a difficult decision. To promote more ethical animal research, scientists must follow the 3Rs principle. Reduction is one of the 3Rs—it i
Publikováno v:
Laboratory animals.
Nurturing a culture of care remains a key strategy and needs to be well integrated in the education programmes for laboratory animal professionals. Addressing attitudes is a complex task that must ensure reflective learning approaches. Teaching strat