Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Jordi J. Cairó"'
Autor:
A. Fontova, Jordi J. Cairó, Ramón Román, Martí Lecina, P. Comas, I. Martínez-Monge, Antoni Casablancas
Publikováno v:
Applied Microbiology and Biotechnology. 103:6903-6917
The increasing demand for biopharmaceuticals produced in mammalian cells has driven the industry to enhance the productivity of bioprocesses through intensification of culture process. Fed-batch and perfusion culturing strategies are considered the m
Autor:
Martí Lecina, Leticia Liste-Calleja, Joan Albiol, Jordi J. Cairó, Iván Martínez‐Monge, Joan Miret, Carles Solà
Publikováno v:
Biotechnology and Bioengineering. 116:388-404
At early stages of the exponential growth phase in HEK293 cell cultures, the tricarboxylic acid cycle is unable to process all the amount of NADH generated in the glycolysis pathway, being lactate the main by-product. However, HEK293 cells are also a
Publikováno v:
Cell Engineering ISBN: 9783030798703
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8667ec1481802461e5f30d388bb813cd
https://doi.org/10.1007/978-3-030-79871-0_16
https://doi.org/10.1007/978-3-030-79871-0_16
Autor:
Jordi J. Cairó, Jordi Prat, Carlos J. Paredes, P. Comas, Antoni Casablancas, David Catalán-Tatjer, Iván Martínez-Monge, Martí Lecina
Publikováno v:
Martínez-Monge, I, Comas, P, Catalán-Tatjer, D, Prat, J, Casablancas, A, Paredes, C, Lecina, M & Cairó, J J 2021, ' The Effect of the Expression of the Antiapoptotic BHRF1 Gene on the Metabolic Behavior of a Hybridoma Cell Line ', Applied Sciences, vol. 11, no. 14, 6258 . https://doi.org/10.3390/app11146258
Applied Sciences, Vol 11, Iss 6258, p 6258 (2021)
Applied Sciences
Volume 11
Issue 14
Applied Sciences, Vol 11, Iss 6258, p 6258 (2021)
Applied Sciences
Volume 11
Issue 14
One of the most important limitations of mammalian cells-based bioprocesses, and particularly hybridoma cell lines, is the accelerated metabolism related to glucose and glutamine consumption. The high uptake rates of glucose and glutamine (i.e., the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d632ae8f68cde40a306599decd517418
https://orbit.dtu.dk/en/publications/9877a23e-a569-424b-9313-e61c2470184e
https://orbit.dtu.dk/en/publications/9877a23e-a569-424b-9313-e61c2470184e
Autor:
Ramón Román, Jordi J. Cairó, Sarah Cianférani, Antoni Casablancas, Mercè Farràs, Joan Miret, Marc Camps, Stéphane Erb
Publikováno v:
ChemistrySelect
ChemistrySelect, Wiley, 2020, 5 (11), pp.3187-3190. ⟨10.1002/slct.201903913⟩
ChemistrySelect, Wiley, 2020, 5 (11), pp.3187-3190. ⟨10.1002/slct.201903913⟩
International audience; Cysteine‐based conjugation is one of the main antibody conjugation strategies for generating both heterogeneous and homogeneous Antibody Drug Conjugates (ADCs), being the reduction of the antibody a crucial step in these pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74bd39fb429d39b4e4667b57acfeb77b
https://hal.archives-ouvertes.fr/hal-02892397
https://hal.archives-ouvertes.fr/hal-02892397
Autor:
Anthony Ehkirch, Ramón Román, Joan Miret, Antoni Casablancas, Sarah Cianférani, Marc Camps, Stéphane Erb, Mercè Farràs, Jordi J. Cairó, Óscar Martínez, Xavier Pujol
Publikováno v:
mAbs
mAbs, Taylor & Francis, 2020, 12 (1), pp.1702262. ⟨10.1080/19420862.2019.1702262⟩
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
mAbs, Taylor & Francis, 2020, 12 (1), pp.1702262. ⟨10.1080/19420862.2019.1702262⟩
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
International audience; Despite advances in medical care, cancer remains a major threat to human health. Antibody-drug conjugates (ADCs) are a promising targeted therapy to overcome adverse side effects to normal tissues. In this field, the current c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::512b15060963ddb225beeb96aed1745f
https://hal.archives-ouvertes.fr/hal-03073004/document
https://hal.archives-ouvertes.fr/hal-03073004/document
Publikováno v:
Animal Cell Biotechnology ISBN: 9781071601907
The platforms for bioprocess development have been developed in parallel to the needs of the manufacturing industry of biopharmaceuticals, aiming to ensure the quality and safety of their products. In this sense, Quality by Design (QbD) and Process A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c432da8fd8871de98b0d28aedb4a673
https://doi.org/10.1007/978-1-0716-0191-4_6
https://doi.org/10.1007/978-1-0716-0191-4_6
Autor:
Jordi J. Cairó, Jonatan López-Repullo, P. Comas, A. Fontova, Iván Martínez‐Monge, Martí Lecina, Ramon Bragós
Publikováno v:
Journal of Chemical Technology & Biotechnology. 93:1757-1766
This is the peer reviewed version of the following article: [Fontova, A. , Lecina, M. , Lopez‐Repullo, J. , Martinez‐Monge, I. , Comas, P. , Bragos, R. and Cairo, J. J. (2018), A simplified implementation of the stationary liquid mass balance met
Publikováno v:
Journal of Biotechnology. 239:57-60
Efficient production and secretion of recombinant proteins in mammalian cell lines relies in a combination of genetic, metabolic and culture strategy factors. The present work assesses the influence of two key genetic components of expression vectors
Autor:
Antoni Casablancas, Jordi J. Cairó, Óscar Martínez, Ramón Román, Marc Camps, Xavier Pujol, Mercè Farràs, Joan Miret
Publikováno v:
BMC Molecular and Cell Biology
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-9 (2020)
Recercat. Dipósit de la Recerca de Catalunya
instname
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-9 (2020)
Recercat. Dipósit de la Recerca de Catalunya
instname
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Background Monoclonal antibodies (mAbs) and their derivatives have become one of the most important classes of therapeutic drugs. Their multiple applications increased the interest for understanding their complex structure. In vivo, animal cells are