Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Jordi Bermúdez"'
Autor:
Anna Vidal-Alabró, Alícia G. Gómez-Valadés, Andrés Méndez-Lucas, Jordi Llorens, Ramon Bartrons, Jordi Bermúdez, Jose C. Perales
Publikováno v:
International Journal of Endocrinology, Vol 2011 (2011)
Recent reports point out the importance of the complex GK-GKRP in controlling glucose and lipid homeostasis. Several GK mutations affect GKRP binding, resulting in permanent activation of the enzyme. We hypothesize that hepatic overexpression of a mu
Externí odkaz:
https://doaj.org/article/c70250b757ab48f0bf0ce4e04dce12c4
Autor:
Petra Hyroššová, Ernest Cutz, Shawn C. Burgess, Jana Semakova, Andrés Méndez-Lucas, Jose C. Perales, Soledad Alcántara, Jordi Bermúdez
Publikováno v:
Journal of Physiology and Biochemistry. 73:89-98
Whole body cytosolic phosphoenolpyruvate carboxykinase knockout (PEPCK-C KO) mice die early after birth with profound hypoglycemia therefore masking the role of PEPCK-C in adult, non-gluconeogenic tissues where it is expressed. To investigate whether
Publikováno v:
European Journal of Pharmacology. 659:259-264
Fructose 1,6 biphosphate (F1,6BP) exerts a protective effect in several in vitro models of induced injury and in isolated organs; however, few studies have been performed using in vivo hypothermia. Here we studied the effects of deep hypothermia (21
Autor:
Joan Gil, Teresa Roig, Jordi Bermúdez, Jordi Boada, Roser Calafell, Jose C. Perales, Antonio F. Santidrian
Publikováno v:
European Journal of Pharmacology. 610:128-133
Fructose 1,6-P2 (F1,6BP) protects rat liver against experimental hepatitis induced by galactosamine (GalN) by means of two parallel effects: prevention of inflammation, and reduction of hepatocyte sensitization to tumour necrosis factor-alpha (TNF-al
Publikováno v:
Critical Care Medicine. 34:807-814
Fructose 1,6-bisphosphate (F1,6BP) protects organs against a wide range of challenges involving inflammation. We hypothesized that the primary action of F1,6BP is to prevent macrophage activation and cytokine release. Our aim was to determine the tis
Publikováno v:
European Journal of Pharmacology. 517:158-164
Inhibition of glycolysis at the phosphofructo-1-kinase step slows cell growth. For this reason, overexpression of fructose-2,6-bisphosphatase is a potential target for antineoplasic treatments. However, therapeutic objectives may be compromised by si
Publikováno v:
Chemistry and Physics of Lipids. 104:133-148
Interaction between serum components and liposomes is an oxygen-dependent exothermic process. We studied the interaction of 100 nm extruded liposomes (bearing positive, negative or no charge) with foetal calf serum by 1H NMR and 13C NMR, in order to
Publikováno v:
ResearcherID
MPP(+), the major metabolite of the Parkinsonism-inducing compound MPTP, responsible for the destruction of the nigrostriatal pathway in primates and rodents, has been assayed in isolated rat liver mitochondria in the presence of physiological concen
Publikováno v:
Scopus-Elsevier
The relationship between the protective effect of fructose 1,6-bisphosphate (F-1,6-P2) against cell injury and the modifications produced in the metabolic fluxes and in the membrane permeability to K+ was studied in isolated rat hepatocytes. Incubati
Autor:
Jordi Bermúdez, Nishanth E. Sunny, TianTeng He, Shawn C. Burgess, Santhosh Satapati, Andrés Méndez-Lucas, Joao A.G. Duarte, Xiaorong Fu, Jose C. Perales
Background & Aims Hepatic gluconeogenesis helps maintain systemic energy homeostasis by compensating for discontinuities in nutrient supply. Liver-specific deletion of cytosolic phosphoenolpyruvate carboxykinase (PEPCK-C) abolishes gluconeogenesis fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b03ff78c4cf98610d1ad18e67b04074
https://europepmc.org/articles/PMC3910155/
https://europepmc.org/articles/PMC3910155/