Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Jordi Bella"'
Publikováno v:
Marine Drugs, Vol 21, Iss 2, p 59 (2023)
Collagen is the most ubiquitous biomacromolecule found in the animal kingdom and is commonly used as a biomaterial in regenerative medicine therapies and biomedical research. The collagens used in these applications are typically derived from mammali
Externí odkaz:
https://doaj.org/article/e57d7cd7f0814dcfa17c0f0d50380819
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Formation of mature bone-resorbing cells through osteoclastogenesis is required for the continuous remodeling and repair of bone tissue. In aging and disease this process may become aberrant, resulting in excessive bone degradation and fragility frac
Externí odkaz:
https://doaj.org/article/e5e32e1900564de7a6e6c19da3575d4e
Autor:
Mattia Vitale, Cosimo Ligorio, Ian P. Smith, Stephen M. Richardson, Judith A. Hoyland, Jordi Bella
Publikováno v:
Gels, Vol 8, Iss 5, p 254 (2022)
Hydrogel biomaterials mimic the natural extracellular matrix through their nanofibrous ultrastructure and composition and provide an appropriate environment for cell–matrix and cell–cell interactions within their polymeric network. Hydrogels can
Externí odkaz:
https://doaj.org/article/b70fff686a1743f8a2151b3168257373
Autor:
Deepankar Gahloth, Graham Heaven, Thomas A. Jowitt, A. Paul Mould, Jordi Bella, Clair Baldock, Philip Woodman, Lydia Tabernero
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract HD-PTP is a tumour suppressor phosphatase that controls endocytosis, down-regulation of mitogenic receptors and cell migration. Central to its role is the specific recruitment of critical endosomal sorting complexes required for transport (E
Externí odkaz:
https://doaj.org/article/fb9b761d30ea4a3cbb093b0b72f678dd
Autor:
Neelanjana Ghosh, Thomas J McKillop, Thomas A Jowitt, Marjorie Howard, Heather Davies, David F Holmes, Ian S Roberts, Jordi Bella
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e37872 (2012)
The genome sequences of enterohaemorrhagic E. coli O157:H7 strains show multiple open-reading frames with collagen-like sequences that are absent from the common laboratory strain K-12. These putative collagens are included in prophages embedded in O
Externí odkaz:
https://doaj.org/article/0739a08be43d43e18be9cd43f7a69321
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e7028 (2009)
Decorin is the archetypal small leucine rich repeat proteoglycan of the vertebrate extracellular matrix (ECM). With its glycosaminoglycuronan chain, it is responsible for stabilizing inter-fibrillar organization. Type I collagen is the predominant me
Externí odkaz:
https://doaj.org/article/a55850f36aa44b0794e4d17e2223dcc1
Publikováno v:
Frontiers in Cell and Developmental Biology
Nedeva, I, Vitale, M, Elson, A, Hoyland, J & Bella, J 2021, ' Role of OSCAR Signaling in Osteoclastogenesis and Bone Disease ', Front Cell Dev Biol, vol. 9, 641162 . https://doi.org/10.3389/fcell.2021.641162
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Nedeva, I, Vitale, M, Elson, A, Hoyland, J & Bella, J 2021, ' Role of OSCAR Signaling in Osteoclastogenesis and Bone Disease ', Front Cell Dev Biol, vol. 9, 641162 . https://doi.org/10.3389/fcell.2021.641162
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Formation of mature bone-resorbing cells through osteoclastogenesis is required for the continuous remodeling and repair of bone tissue. In aging and disease this process may become aberrant, resulting in excessive bone degradation and fragility frac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64bd356a1791e82e8c802e37353a4dd7
https://doi.org/10.3389/fcell.2021.641162
https://doi.org/10.3389/fcell.2021.641162
Autor:
Christopher H. Allan, Mattia Vitale, Jordi Bella, Nigel Hodson, Cosimo Ligorio, Judith A. Hoyland, Stephen M. Richardson, Bethan S. McAvan
Publikováno v:
Vitale, M, Ligorio, C, Mcavan, B, Hodson, N, Allan, C, Richardson, S, Hoyland, J & Bella, J 2022, ' Hydroxyapatite-decorated Fmoc-hydrogel as a bone-mimicking substrate for osteoclast differentiation and culture ', Acta Biomaterialia, vol. 138, pp. 144-154 . https://doi.org/10.1016/j.actbio.2021.11.011
Acta Biomaterialia
Acta Biomaterialia
Hydrogels are water-swollen networks with great potential for tissue engineering applications. However, their use in bone regeneration is often hampered due to a lack of materials’ mineralization and poor mechanical properties. Moreover, most studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1815e5c479e7981bfdba7667e4d2e83e
https://doi.org/10.2139/ssrn.3895614
https://doi.org/10.2139/ssrn.3895614
Autor:
Jordi Bella
Publikováno v:
Biochemical Journal. 473:1001-1025
The main features of the triple helical structure of collagen were deduced in the mid-1950s from fibre X-ray diffraction of tendons. Yet, the resulting models only could offer an average description of the molecular conformation. A critical advance c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af91c817545261eb2073bdfcbda6047c
https://doi.org/10.1042/bj20151169
https://doi.org/10.1042/bj20151169
Autor:
Jordi, Bella, David J S, Hulmes
Publikováno v:
Sub-cellular biochemistry. 82
Fibrillar collagens (types I, II, III, V, XI, XXIV and XXVII) constitute a sub-group within the collagen family (of which there are 28 types in humans) whose functions are to provide three-dimensional frameworks for tissues and organs. These networks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7d6b09ac38461b5dc9b8916b57a06c04
https://pubmed.ncbi.nlm.nih.gov/28101870
https://pubmed.ncbi.nlm.nih.gov/28101870