Zobrazeno 1 - 10
of 215
pro vyhledávání: '"Jordi A. Matías‐Guiu"'
Autor:
Juan I. López-Carbonero, Irene García-Toledo, Laura Fernández-Hernández, Pablo Bascuñana, María J. Gil-Moreno, Jordi A. Matías-Guiu, Silvia Corrochano
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-20 (2024)
Abstract TDP-43 proteinopathies are a heterogeneous group of neurodegenerative disorders that share the presence of aberrant, misfolded and mislocalized deposits of the protein TDP-43, as in the case of amyotrophic lateral sclerosis and some, but not
Externí odkaz:
https://doaj.org/article/e463fc941f6c458eb3db83c652187611
Autor:
Laura Hernández-Lorenzo, Fernando García-Gutiérrez, Ana Solbas-Casajús, Silvia Corrochano, Jordi A. Matías-Guiu, Jose L. Ayala
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Alzheimer's disease (AD) shows a high pathological and symptomatological heterogeneity. To study this heterogeneity, we have developed a patient stratification technique based on one of the most significant risk factors for the development o
Externí odkaz:
https://doaj.org/article/73528481fabb427199a0c3c582a39d51
Autor:
Laura Hernández-Lorenzo, Fernando García-Gutiérrez, Ana Solbas-Casajús, Silvia Corrochano, Jordi A. Matías-Guiu, Jose L. Ayala
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/53358be62bb04cb0a2448b87995f43f5
Autor:
Laura Hernández-Lorenzo, Markus Hoffmann, Evelyn Scheibling, Markus List, Jordi A. Matías-Guiu, Jose L. Ayala
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Alzheimer's disease (AD) is a neurodegenerative disease whose molecular mechanisms are activated several years before cognitive symptoms appear. Genotype-based prediction of the phenotype is thus a key challenge for the early diagnosis of AD
Externí odkaz:
https://doaj.org/article/aaf51446d8694603b4b659a20ab94bf5
Autor:
Jordi A. Matías-Guiu
Publikováno v:
Kranion, Vol 18, Iss 2 (2023)
La inteligencia artificial incluye una serie de técnicas de aplicación e interés creciente en medicina. El campo de la neurología cognitiva y las demencias se enfrenta a múltiples retos, incluyendo la necesidad de realizar un diagnóstico más p
Externí odkaz:
https://doaj.org/article/b660d205e5da441eb4317c3023ec57f5
Autor:
Ulises Gómez-Pinedo, Jordi A. Matías-Guiu, Denise Ojeda-Hernandez, Sarah de la Fuente-Martin, Ola Mohamed-Fathy Kamal, Maria Soledad Benito-Martin, Belen Selma-Calvo, Paloma Montero-Escribano, Jorge Matías-Guiu
Publikováno v:
Cells, Vol 12, Iss 11, p 1515 (2023)
The implantation of oligodendrocyte precursor cells may be a useful therapeutic strategy for targeting remyelination. However, it is yet to be established how these cells behave after implantation and whether they retain the capacity to proliferate o
Externí odkaz:
https://doaj.org/article/68b49f85671e47a0bb366570e91442d3
Autor:
Doddy Denise Ojeda-Hernández, Mercedes A. Hernández-Sapiéns, Edwin E. Reza-Zaldívar, Alejandro Canales-Aguirre, Jordi A. Matías-Guiu, Jorge Matías-Guiu, Juan Carlos Mateos-Díaz, Ulises Gómez-Pinedo, Francisco Sancho-Bielsa
Publikováno v:
Life, Vol 12, Iss 9, p 1417 (2022)
Current efforts to find novel treatments that counteract multiple sclerosis (MS) have pointed toward immunomodulation and remyelination. Currently, cell therapy has shown promising potential to achieve this purpose. However, disadvantages such as poo
Externí odkaz:
https://doaj.org/article/a1cae03bdd7845e49f1211bcf7f89bb1
Autor:
Inmaculada Sanclemente-Alaman, Lidia Moreno-Jiménez, María Soledad Benito-Martín, Alejandro Canales-Aguirre, Jordi A. Matías-Guiu, Jorge Matías-Guiu, Ulises Gómez-Pinedo
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
IntroductionThe response to the SARS-CoV-2 coronavirus epidemic requires increased research efforts to expand our knowledge of the disease. Questions related to infection rates and mechanisms, the possibility of reinfection, and potential therapeutic
Externí odkaz:
https://doaj.org/article/61edc652e91449629ed823905dc5a367
Autor:
Jorge Matías-Guiu, Jordi A. Matías-Guiu, Paloma Montero-Escribano, Juan A. Barcia, Alejandro A. Canales-Aguirre, Juan C. Mateos-Diaz, Ulises Gómez-Pinedo
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
The repair of demyelinated lesions is a key objective in multiple sclerosis research. Remyelination fundamentally depends on oligodendrocyte progenitor cells (OPC) reaching the lesion; this is influenced by numerous factors including age, disease pro
Externí odkaz:
https://doaj.org/article/3f112d4f2457472491dab31822b5a8bb
Autor:
Patricia Gómez-Iglesias, Jesús Porta-Etessam, Teresa Montalvo, Adrián Valls-Carbó, Vicente Gajate, Jordi A. Matías-Guiu, Beatriz Parejo-Carbonell, Nuria González-García, David Ezpeleta, José Miguel Láinez, Jorge Matías-Guiu
Publikováno v:
Frontiers in Public Health, Vol 8 (2020)
Introduction: Since the beginning of the Covid-19 epidemic produced by SARS2-Cov virus, olfactory alterations have been observed at a greater frequency than in other coronavirus epidemics. While olfactory alterations may be observed in patients with
Externí odkaz:
https://doaj.org/article/bb4c15dde522493483d5a623cf4925c9