Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Jordi, Xaus"'
Autor:
Fernando Cavalcanti, Elena Gonzalez-Rey, Mario Delgado, Clara P. Falo, Leyre Mestre, Carmen Guaza, Francisco O’Valle, Michele M. P. Lufino, Jordi Xaus, Cristina Mascaró, Serena Lunardi, Natalia Sacilotto, Paola Dessanti, David Rotllant, Xavier Navarro, Mireia Herrando-Grabulosa, Carlos Buesa, Tamara Maes
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1420 (2022)
Lysine specific demethylase 1 (LSD1; also known as KDM1A), is an epigenetic modulator that modifies the histone methylation status. KDM1A forms a part of protein complexes that regulate the expression of genes involved in the onset and progression of
Externí odkaz:
https://doaj.org/article/df089ff6678843aa91f71f1d603fc7ce
Autor:
Michele M.P. Lufino, Serena Lunardi, Natalia Sacilotto, Tamara Maes, Mireia Herrando-Grabulosa, David Rotllant, Carlos Buesa, Jordi Xaus, Paola Dessanti, Carmen Guaza, Xavier Navarro, Elena Gonzalez-Rey, Cristina Mascaró, Mario Delgado, F. L. Cavalcanti, Leyre Mestre
Background Vafidemstat (ORY-2001) is a clinical stage inhibitor of the Lysine Specific Demethylase KDM1A in development for treatment of neurodegenerative and psychiatric diseases. KDM1A demethylates H3K4me1/2 and together with the histone deacetylas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc502a6fe4bd89e62039ecf96871e3e
https://doi.org/10.21203/rs.3.rs-114482/v4
https://doi.org/10.21203/rs.3.rs-114482/v4
Publikováno v:
Alzheimer's & Dementia. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e891c09ec15170836cf37c685bf5c42
https://doi.org/10.1002/alz.042809
https://doi.org/10.1002/alz.042809
Publikováno v:
Alzheimer's & Dementia. 15:P572-P573
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cef87781ced5f1ae397e9adb4c0f4687
https://doi.org/10.1016/j.jalz.2019.06.1227
https://doi.org/10.1016/j.jalz.2019.06.1227
Autor:
Roger Bullock, Sonia Gutierrez, Jordi Xaus, Mabel Arevalo, Carlos Buesa, Tim C. P. Somervaille
Publikováno v:
Blood. 134:3839-3839
Introduction: Acute Myeloid Leukemia (AML) is an elderly disease with a rising incidence in the past decades. Probability to achieve complete remission and survival rates decrease with age with standard chemotherapy options leading to very poor outco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::125c8e4400e5ee181664f4b5ad5cae22
https://doi.org/10.1182/blood-2019-125121
https://doi.org/10.1182/blood-2019-125121
Autor:
Juan Román, Antonio Zarzuelo, Julio Gálvez, Jordi Xaus, Manuel Merlos, Margarita Cueto-Sola, B Arribas, Desirée Camuesco, Natividad Garrido-Mesa, Mònica Comalada, G Janer, Dolors Balsa, Elvira Bailón, María Elena Rodríguez-Cabezas
Publikováno v:
British Journal of Pharmacology. 165:729-740
BACKGROUND AND PURPOSE Dersalazine sodium (DS) is a new chemical entity formed by combining, through an azo bond, a potent platelet activating factor (PAF) antagonist (UR-12715) with 5-aminosalicylic acid (5-ASA). DS has been demonstrated to have ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45907922e6002cef63fe19ec83fd5f50
https://doi.org/10.1111/j.1476-5381.2011.01598.x
https://doi.org/10.1111/j.1476-5381.2011.01598.x
Autor:
Antonio Zarzuelo, Pilar Utrilla, Julio Gálvez, Natividad Garrido-Mesa, Antonio Celada, Margarita Cueto-Sola, Mònica Comalada, Ana Nieto, Jordi Xaus, Elvira Bailón
Publikováno v:
Inflammatory Bowel Diseases. 17:2087-2101
Background: The dinitrofluorobenzene/dinitrosulfonic acid (DNFB/DNS) model was originally described as an experimental model of intestinal inflammation resembling human ulcerative colitis (UC). Due to the absence of acceptable UC experimental models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3aa22f9a99b0f21119b9be82894dab38
https://doi.org/10.1002/ibd.21586
https://doi.org/10.1002/ibd.21586
Autor:
Jordi Xaus, Juan M. Rodríguez, Julio Boza, Federico Lara-Villoslada, Marta Gómez, José Maldonado, Saleta Sierra, Mónica Olivares, Lluis Sempere
Publikováno v:
Nutrition. 26:1082-1087
Objective Intestinal microbiota plays an important role in the prevention of certain diseases during the pediatric years. Thus, there is an increasing interest in the addition of probiotics to infant formulas. The aim of this study was to evaluate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52a0ff87f3a2b075abcbe5cbb3b50fff
https://doi.org/10.1016/j.nut.2009.08.023
https://doi.org/10.1016/j.nut.2009.08.023
Autor:
Leónides Fernández, Mónica Olivares, Rocio Martin, Manuela Pérez, Jordi Xaus, Celina Torre, Juan M. Rodríguez
Publikováno v:
The Veterinary Journal. 185:193-198
Canine milk protects puppies against infectious diseases through a variety of mechanisms. In this study, the presence of potentially probiotic lactic acid bacteria grown on MRS-Cys agar plates from milk of nine bitches was investigated. The Gram posi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92b6319de8ae84b2e9772b9a82487ea2
https://doi.org/10.1016/j.tvjl.2009.04.014
https://doi.org/10.1016/j.tvjl.2009.04.014
Autor:
Mónica Olivares, Ana Martinez-Cañavate, Jordi Xaus, Federico Lara-Villoslada, Julio Romero, Julio Boza, Saleta Sierra, José Maldonado
Publikováno v:
Pediatric Allergy and Immunology. 20:592-600
The increase in the prevalence of allergic diseases in children has been attributed to an unbalanced immune response probably due to environmental factors. The immunoregulatory properties of probiotic bacteria could balance the disequilibrium in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62dcb3e086c6279a01277b60d8c316b9
https://doi.org/10.1111/j.1399-3038.2008.00833.x
https://doi.org/10.1111/j.1399-3038.2008.00833.x