Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Jordi, Robles"'
Publikováno v:
Journal of Molecular Recognition. 29:142-150
Isothermal titration calorimetry (ITC) is a powerful technique able to evaluate the energetics of target-drug binding within the context of drug discovery. In this work, the interactions of RNAs reproducing bacterial and human ribosomal A-site, with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0083b736c2783bec383dfe463481aa8a
https://doi.org/10.1002/jmr.2513
https://doi.org/10.1002/jmr.2513
Publikováno v:
European Journal of Organic Chemistry. 2010:3102-3109
An alternative and straightforward method to prepare aminoglycoside–dinucleotide and –diPNA conjugates is reported, which is based on copper-catalyzed Huisgen azide-alkyne cycloaddition (“click chemistry” ligation) assisted by microwave irrad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::345cd83c5cfb053534a789d3344c0b0a
https://doi.org/10.1002/ejoc.201000182
https://doi.org/10.1002/ejoc.201000182
Publikováno v:
European Journal of Organic Chemistry. 2009:1398-1406
Solid-phase procedures have been used to prepare six dipyrrole-containing DNA ligands that combine (guanin-9-yl)acetyl, (guanin-7-yl)acetyl or acetyl moieties at the N-terminal end and two lysines or a (dimethylamino)propyl group at the C terminus. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a142cd673313cb03732fcc6975583fb
https://doi.org/10.1002/ejoc.200800892
https://doi.org/10.1002/ejoc.200800892
Publikováno v:
Tetrahedron. 65:1171-1179
Morpholinoamidines were devised as new cationic units in oligonucleotides, by combining morpholino-nucleosides (to simplify the nomenclature, we will use the term morpholino-nucleosides to refer to nucleoside analogues in which the ribose ring was tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51429eed5b6f38824742a42e529fc575
https://doi.org/10.1016/j.tet.2008.11.069
https://doi.org/10.1016/j.tet.2008.11.069
Autor:
Jordi Robles, Enrique Pedroso, José Ramón Blas, José-Antonio Ortega, Modesto Orozco, Anna Grandas
Publikováno v:
Organic Letters. 9:4503-4506
Melting temperatures of DNA duplexes containing the phenoxazine (P) and G-clamp (X) cytosine analogues exhibited a strong and unusual dependence on the nucleoside flanking the modified nucleobase, and the same trend was observed in PNA-DNA duplexes i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ab65b19dc3b2b0b7ae689ffd045727
https://doi.org/10.1021/ol701826x
https://doi.org/10.1021/ol701826x
Autor:
Alejandro Trapote, Jorge Ramajo, Encarnación Martínez-Salas, Anna Grandas, Gloria Lozano, Jordi Robles, Xavier Elduque, Enrique Pedroso
Publikováno v:
RNA Biology
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
The internal ribosome entry site (IRES) element located at the 5’untranslated genomic region of various RNA viruses mediates cap-independent initiation of translation. Picornavirus IRES activity is highly dependent on both its structural organizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7903cafaa80bbe845c1fdb21a085e357
https://pubmed.ncbi.nlm.nih.gov/25775053
https://pubmed.ncbi.nlm.nih.gov/25775053
Autor:
Modesto Orozco, Ramon Eritja, Anna Grandas, Jordi Robles, Francisco J. Luque, Enrique Pedroso
Publikováno v:
Current Organic Chemistry. 6:1333-1368
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d693978432ce3915d0e5a86b597bf1ed
https://doi.org/10.2174/1385272023373482
https://doi.org/10.2174/1385272023373482
Autor:
Maite Beltrán, Yolanda Pérez, Vicente Marchán, Anna Grandas, Enrique Pedroso, Jordi Robles, Isaura Travesset
Publikováno v:
Tetrahedron. 58:6965-6978
Nucleopeptides with no restriction in the amino acid composition can be synthesized using stepwise solid-phase methodology. Best conditions for the protection of arginine and cysteine, as well as for the final deprotection treatment are established,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3f825a4b81bb47d44e0a06894faaefc
https://doi.org/10.1016/s0040-4020(02)00793-7
https://doi.org/10.1016/s0040-4020(02)00793-7
Publikováno v:
Journal of molecular recognition : JMR. 29(4)
Isothermal titration calorimetry (ITC) is a powerful technique able to evaluate the energetics of target-drug binding within the context of drug discovery. In this work, the interactions of RNAs reproducing bacterial and human ribosomal A-site, with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::703545f8515c4e1aa8c09e7b1ddd7c89
https://pubmed.ncbi.nlm.nih.gov/26530431
https://pubmed.ncbi.nlm.nih.gov/26530431
Publikováno v:
Tetrahedron. 57:179-194
Oligonucleotides incorporating 4-guanidino-2-pyrimidinone nucleobases have been prepared. These nucleobase analogues were designed to mimic the double hydrogen bond donor pattern of protonated cytosines in parallel triple helices. Guanidine-, N-methy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96e0e65dd219942be07c5c0a3a4bbac4
https://doi.org/10.1016/s0040-4020(00)00991-1
https://doi.org/10.1016/s0040-4020(00)00991-1