Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jorden L. Welker"'
Autor:
Adrienne E. Swanstrom, Robert J. Gorelick, Jorden L. Welker, Fabian Schmidt, Bing Lu, Kelly Wang, William Rowe, Matthew W. Breed, Kristin E. Killoran, Joshua A. Kramer, Duncan Donohue, James D. Roser, Paul D. Bieniasz, Theodora Hatziioannou, Cathi Pyle, James A. Thomas, Charles M. Trubey, Jim Zheng, Wade Blair, Stephen R. Yant, Jeffrey D. Lifson, Gregory Q. Del Prete
Publikováno v:
EBioMedicine, Vol 95, Iss , Pp 104764- (2023)
Summary: Background: Long-acting subcutaneous lenacapavir (LEN), a first-in-class HIV capsid inhibitor approved by the US FDA for the treatment of multidrug-resistant HIV-1 with twice yearly dosing, is under investigation for HIV-1 pre-exposure proph
Externí odkaz:
https://doaj.org/article/b06319c89f9342968fa2a346c4e69436
Autor:
Thomas S. Uldrick, Scott V. Adams, Remi Fromentin, Michael Roche, Steven P. Fling, Priscila H. Gonçalves, Kathryn Lurain, Ramya Ramaswami, Chia-ching Jackie Wang, Robert J. Gorelick, Jorden L. Welker, Liz O’Donoghue, Harleen Choudhary, Jeffrey D. Lifson, Thomas A. Rasmussen, Ajantha Rhodes, Carolin Tumpach, Robert Yarchoan, Frank Maldarelli, Martin A. Cheever, Rafick Sékaly, Nicolas Chomont, Steven G. Deeks, Sharon R. Lewin
Publikováno v:
Sci Transl Med
Science translational medicine, vol 14, iss 629
Uldrick, T S, Adams, S V, Fromentin, R, Roche, M, Fling, S P, Gonçalves, P H, Lurain, K, Ramaswami, R, Jackie Wang, C C, Gorelick, R J, Welker, J L, O'Donoghue, L, Choudhary, H, Lifson, J D, Rasmussen, T A, Rhodes, A, Tumpach, C, Yarchoan, R, Maldarelli, F, Cheever, M A, Sékaly, R, Chomont, N, Deeks, S G & Lewin, S R 2022, ' Pembrolizumab induces HIV latency reversal in people living with HIV and cancer on antiretroviral therapy ', Science Translational Medicine, vol. 14, no. 629, eabl3836 . https://doi.org/10.1126/scitranslmed.abl3836
Science translational medicine, vol 14, iss 629
Uldrick, T S, Adams, S V, Fromentin, R, Roche, M, Fling, S P, Gonçalves, P H, Lurain, K, Ramaswami, R, Jackie Wang, C C, Gorelick, R J, Welker, J L, O'Donoghue, L, Choudhary, H, Lifson, J D, Rasmussen, T A, Rhodes, A, Tumpach, C, Yarchoan, R, Maldarelli, F, Cheever, M A, Sékaly, R, Chomont, N, Deeks, S G & Lewin, S R 2022, ' Pembrolizumab induces HIV latency reversal in people living with HIV and cancer on antiretroviral therapy ', Science Translational Medicine, vol. 14, no. 629, eabl3836 . https://doi.org/10.1126/scitranslmed.abl3836
In people living with HIV (PLWH) on antiretroviral therapy (ART), virus persists in a latent form where there is minimal transcription or protein expression. Latently infected cells are a major barrier to curing HIV. Increasing HIV transcription and
Autor:
Nagalingeswaran Kumarasamy, Sivaporn Gatechompol, Jeffrey D. Lifson, Stephen J. Kerr, Frank Maldarelli, Lu Zheng, Yajing Bao, Robert J. Gorelick, Jorden L Welker, Joseph J. Eron, Kiat Ruxrungtham, James Hakim, Mina C. Hosseinipour, Anchalee Avihingsanon
Publikováno v:
Medicine. 100:e26817
In order to design effective strategies to eradicate the HIV, an understanding of persistent viral reservoirs is needed. Many studies have demonstrated HIV residual viremia prevalence in high income countries, data from low- and middle-income countri