Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jorden Kass"'
FRI-191-EDP-514, a novel HBV core inhibitor with potent antiviral activity both in vitro and in vivo
Autor:
Hui Cao, Michael Vaine, Bryan Goodwin, Li-Juan Jiang, Kellye Daniels, Jorden Kass, Li Wei, Yao-Ling Qiu, Xiaowen Peng, Kai Lin, Xuri Gao, Yat Sun Or, Victor Dellisola, Susan Clugston
Publikováno v:
Journal of Hepatology. 70:e474-e475
Autor:
Hui Chen, Jing Zhang, Susan A. Jones, Lihui Liu, Zhong Li, Nilesh K. Banavali, Hongmin Li, Arun K. Ghosh, Laura D. Kramer, Jorden Kass
Publikováno v:
Antiviral Research. 97:232-239
The flavivirus methyltransferase (MTase) sequentially methylates the N-7 and 2′-O positions of the viral RNA cap (GpppA-RNA→m7GpppA-RNA→m7GpppAm-RNA), using S-adenosyl- l -methionine (SAM) as a methyl donor. We report here the synthesis and bio
Autor:
Xuri Gao, M. Vaine, Yat Sun Or, Li Wei, Kai Lin, S. Clugston, Li-Juan Jiang, Yao-Ling Qiu, K. Daniels, Xiaowen Peng, Jorden Kass, Hui Cao
Publikováno v:
Journal of Hepatology. 68:S19
Publikováno v:
Organic Preparations and Procedures International. 38:480-483
Publikováno v:
ChemInform. 44
A mild tandem olefination/Prins cyclization of hex-5-en-1-ols with a variety of aldehydes in the presence of phosphine ligands (I)-(III) is developed.
We developed a copper(II) triflate-bisphosphine complex catalyzed olefin migration and Prins cyclization which lead to the synthesis of substituted tetrahydropyran derivatives. The protocol is convenient and a variety of substituted tetrahydropyrans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c73c23447ed0f5c4864d32b715b406d
https://europepmc.org/articles/PMC6237189/
https://europepmc.org/articles/PMC6237189/
Publikováno v:
ChemInform. 43
The scope of the Cu(OTf)2—bisphoshine catalyzed tandem olefin migration and Prins cyclization of the hexenol (I) with aldehydes is investigated using a quite stable bisphoshine ligand with low air-sensitivity.
In situ-generated (bis-DPPMB)-Cu(OTf)(2) complex has been examined to catalyze a tandem olefin migration and Prins cyclization of an alkenol with various aldehydes. The reaction proceeded with electron-rich aromatic aldehydes at room temperature and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3d490435f6306172d05e5e0dbe00483
https://europepmc.org/articles/PMC3383828/
https://europepmc.org/articles/PMC3383828/
Autor:
Jorden Kass, Arun K. Ghosh
Publikováno v:
Organic letters. 14(2)
A stereoselective synthesis of (−)-viridiofungin A is described. The convergent synthesis utilized a unique highly diastereoselective multicomponent reaction between optically active phenyldihydrofuran and an α-ketoester to provide two chiral cent
Autor:
Arun K. Ghosh, Jorden Kass
Publikováno v:
ChemInform. 41
We have developed a practical synthesis of unique nucleoside derivatives via TiCl4 promoted multicomponent reaction of optically active dihydrofuran, ethyl pyruvate/glyoxylate, and a TMS protected nucleobase in a single-pot operation.