Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Jordane, Preto"'
Autor:
Hubert Gorny, Angélique Mularoni, Jean-Guy Delcros, Céline Freton, Jordane Preto, Isabelle Krimm
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
The mitochondrial voltage-dependent anion channel 1 (VDAC1) plays a central role in metabolism and apoptosis, which makes it a promising therapeutic target. Nevertheless, molecular mechanisms governing VDAC1 functioning remain unclear. Small-molecule
Externí odkaz:
https://doaj.org/article/94fbca4d39914ba4aeb68b72d22f8e76
Autor:
Vijaya L. Damaraju, Maral Aminpour, Michelle Kuzma, Philip Winter, Jordane Preto, Jack Tuszynski, Alexander B.J. McEwan, Michael B. Sawyer
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 3, Pp 847-858 (2021)
Positron emission tomography (PET) using 2‐deoxy‐2‐[18F]fluoro‐d‐glucose ([18F]FDG), a marker of energy metabolism and cell proliferation, is routinely used in the clinic to assess patient response to chemotherapy and to monitor tumor growt
Externí odkaz:
https://doaj.org/article/0ee71f90bba14c2d88d2155aa4242963
Autor:
Jordane Preto, Isabelle Krimm
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 2, p e1008750 (2021)
The voltage-dependent anion channel (VDAC) is a critical β-barrel membrane protein of the mitochondrial outer membrane, which regulates the transport of ions and ATP between mitochondria and the cytoplasm. In addition, VDAC plays a central role in t
Externí odkaz:
https://doaj.org/article/5509697b15ee4bfd936d230340b0bb08
Autor:
Maral Aminpour, Marco Cannariato, Jordane Preto, M. Ehsan Safaeeardebili, Alexia Moracchiato, Domiziano Doria, Francesca Donato, Eric Adriano Zizzi, Marco Agostino Deriu, David E. Scheim, Alessandro D. Santin, Jack Adam Tuszynski
Publikováno v:
Computation, Vol 10, Iss 4, p 51 (2022)
Some clinical studies have indicated activity of ivermectin, a macrocyclic lactone, against COVID-19, but a biological mechanism initially proposed for this anti-viral effect is not applicable at physiological concentrations. This in silico investiga
Externí odkaz:
https://doaj.org/article/e6955eea9d134214b507a187472c4042
Autor:
Aarat P. Kalra, Sahil D. Patel, Asadullah F. Bhuiyan, Jordane Preto, Kyle G. Scheuer, Usman Mohammed, John D. Lewis, Vahid Rezania, Karthik Shankar, Jack A. Tuszynski
Publikováno v:
Nanomaterials, Vol 10, Iss 2, p 265 (2020)
Microtubules are hollow cylindrical polymers composed of the highly negatively-charged (~23e), high dipole moment (1750 D) protein α, β- tubulin. While the roles of microtubules in chromosomal segregation, macromolecular transport, and cell migrati
Externí odkaz:
https://doaj.org/article/dd1025df93e94a7a9e969f822bd839da
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0202141 (2018)
Tubulin heterodimers are the building blocks of microtubules and disruption of their dynamics is exploited in the treatment of cancer. Electric fields at certain frequencies and magnitudes are believed to do the same. Here, the tubulin dimer's respon
Externí odkaz:
https://doaj.org/article/197c95d171f448e5acb8b52b1880577c
Autor:
Jack A. Tuszynski, Michael B. Sawyer, Vijaya L. Damaraju, Philip Winter, Jordane Preto, Alexander B.J. McEwan, Maral Aminpour, Michelle Kuzma
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 3, Pp 847-858 (2021)
Positron emission tomography (PET) using 2-deoxy-2-[18 F]fluoro-d-glucose ([18 F]FDG), a marker of energy metabolism and cell proliferation, is routinely used in the clinic to assess patient response to chemotherapy and to monitor tumor growth. Treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be13eae69e629421eb604d42b7b91acc
https://doaj.org/article/0ee71f90bba14c2d88d2155aa4242963
https://doaj.org/article/0ee71f90bba14c2d88d2155aa4242963
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1175, p 1175 (2022)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2022, 23 (3), pp.1175. ⟨10.3390/ijms23031175⟩
International Journal of Molecular Sciences; Volume 23; Issue 3; Pages: 1175
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2022, 23 (3), pp.1175. ⟨10.3390/ijms23031175⟩
International Journal of Molecular Sciences; Volume 23; Issue 3; Pages: 1175
The voltage-dependent anion channel 1 (VDAC1) is a crucial mitochondrial transporter which controls the flow of ions and respiratory metabolites entering or exiting mitochondria. As a voltage-gated channel, VDAC1 can switch between a high conducting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::614f4e45b3a519b133d194bc1fee314d
https://www.mdpi.com/1422-0067/23/3/1175
https://www.mdpi.com/1422-0067/23/3/1175
Autor:
Urszula Majcher, Greta Klejborowska, Magdalena Kaik, Ewa Maj, Joanna Wietrzyk, Mahshad Moshari, Jordane Preto, Jack A. Tuszynski, Adam Huczyński
Publikováno v:
Cells, Vol 7, Iss 11, p 216 (2018)
Specific modifications of colchicine followed by synthesis of its analogues have been tested in vitro with the objective of lowering colchicine toxicity. Our previous studies have clearly shown the anticancer potential of double-modified colchicine d
Externí odkaz:
https://doaj.org/article/d90acafa95da486eb8b4778010df8387
Autor:
Ilaria Nardecchia, Jeremie Torres, Mathias Lechelon, Valeria Giliberti, Michele Ortolani, Philippe Nouvel, Matteo Gori, Yoann Meriguet, Irene Donato, Jordane Preto, Luca Varani, James Sturgis, Marco Pettini
Publikováno v:
Physical Review X, Vol 8, Iss 3, p 031061 (2018)
We describe the activation of out-of-equilibrium collective oscillations of a macromolecule as a classical phonon condensation phenomenon. If a macromolecule is modeled as an open system—that is, it is subjected to an external energy supply and is
Externí odkaz:
https://doaj.org/article/4d0de9da12d04cf0a3f9e2c86490d39c