Vitamin D supplementation modulates autophagy in the pristane-induced lupus model

Autor: Manuela dos Santos, Jordana Miranda de Souza Silva, Bárbara Jonson Bartikoski, Eduarda Correa Freitas, Amanda Busatto, Rafaela Cavalheiro do Espírito Santo, Odirlei Andre Monticielo, Ricardo Machado Xavier

Publikováno v: Advances in Rheumatology, Vol 62, Iss 1, Pp 1-11 (2022)

Abstract Introduction/objectives Clinical evidence of skeletal muscle involvement is not uncommon in systemic lupus erythematosus (SLE). Because of the poor understanding of signaling pathways involved in SLE muscle wasting, the aim of this study was

Externí odkaz: https://doaj.org/article/31c58d404fab405791acba3f944a2fb0

Vitamin D supplementation ameliorates arthritis but does not alleviates renal injury in pristane-induced lupus model

Autor: Eduarda Correa Freitas, Thaís Evelyn Karnopp, Jordana Miranda de Souza Silva, Rafaela Cavalheiro do Espírito Santo, Thales Hein da Rosa, Mayara Souza de Oliveira, Fabiany da Costa Gonçalves, Francine Hehn de Oliveira, Pedro Guilherme Schaefer, Odirlei André Monticielo

Publikováno v: Autoimmunity, Vol 52, Iss 2, Pp 69-77 (2019)

Systemic lupus erythematosus (SLE) is a multifactorial and autoimmune inflammatory disease with pleomorphic clinical manifestations involving different organs and tissues. The study of different murine models has provided a better understanding of th

Externí odkaz: https://doaj.org/article/ff36340b2d0840c9802e17344cd9ca02

GDF-11 expression is increased in the skeletal muscle of mice with collagen-induced arthritis and is related to physical impairment

Autor: Natália Garcia dos Santos, Bárbara Jonson Bartikoski, Mirian Farinon, Thales Hein da Rosa, Renata Ternus Pedó, Thais Evelyn Karnopp, Rafaela Cavalheiro do Espírito Santo, Jordana Miranda de Souza Silva, Ricardo Machado Xavier

Publikováno v: XXXIX Congresso Brasileiro de Reumatologia.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7c8fa5e311e35d4ebeeef12db96f4c88
https://doi.org/10.47660/cbr.2022.1952

Metabolomic Biomarker Candidates for Skeletal Muscle Loss in the Collagen-Induced Arthritis (CIA) Model

Autor: Mônica Luiza Immig, Vivian de Oliveira Nunes Teixeira, Claiton Viegas Brenol, Andrelise Simões de Almeida, Jordana Miranda de Souza Silva, Eduarda Correa Freitas, Rafaela Cavalheiro do Espírito Santo, Lidiane Isabel Filippin, Marianne Schrader de Oliveira, Priscila Schmidt Lora, Camilla L Bathurst, Paulo V G Alabarse, Mayara Souza de Oliveira, Stephen P. Young, Ricardo Machado Xavier

Publikováno v: Journal of Personalized Medicine
Volume 11
Issue 9
Journal of Personalized Medicine, Vol 11, Iss 837, p 837 (2021)
Repositório Institucional da UFRGS
Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS

There is no consensus for diagnosis or treatment of RA muscle loss. We aimed to investigate metabolites in arthritic mice urine as biomarkers of muscle loss. DBA1/J mice comprised collagen-induced arthritis (CIA) and control (CO) groups. Urine sample

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f464e39f79efc9dc7123b8462629d903

Collagen-induced arthritis as an animal model of rheumatoid cachexia

Autor: Andrelise Simões de Almeida, Paulo Vinicius Gil Alabarse, Ricardo Machado Xavier, Vivian de Oliveira Nunes Teixeira, Mayara Souza de Oliveira, Jordana Miranda de Souza Silva, Priscila Schmidt Lora, Eduarda Correa Freitas, Mônica Luiza Immig, Lidiane Isabel Filippin, Rafaela Cavalheiro do Espírito Santo

Publikováno v: Journal of Cachexia, Sarcopenia and Muscle. 9:603-612

Background Rheumatoid arthritis is characterized by chronic polyarticular synovitis and presents systemic changes that impact quality of life, such as impaired muscle function, seen in up to 66% of the patients. This can progress to severely debilita

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::da04e93ebeabbf13f0c264b34a0bf1d0
https://doi.org/10.1002/jcsm.12280