Metabolic reprogramming of macrophages in the context of type 2 diabetes

Autor: Leonel Witcoski Junior, Jordana Dinorá de Lima, Amanda Girardi Somensi, Lucas Brito de Souza Santos, Giulia Leonel Paschoal, Thalita Suemy Uada, Thais Sibioni Berti Bastos, André Guilherme Portela de Paula, Rebeca Bosso Dos Santos Luz, Andressa Pacheco Czaikovski, Mariana Rodrigues Davanso, Tarcio Teodoro Braga

Publikováno v: European Journal of Medical Research, Vol 29, Iss 1, Pp 1-10 (2024)

Abstract Type 2 diabetes (T2D) is associated with insulin resistance and progressive dysfunction of β-pancreatic cells, leading to persistent hyperglycemia. Macrophages play a crucial role in this context, influencing both the development and progre

Externí odkaz: https://doaj.org/article/1165e7196a844a2a86432e184482cbec

Active learning tools improve the learning outcomes, scientific attitude, and critical thinking in higher education: Experiences in an online course during the COVID ‐19 pandemic

Autor: Marcel I. Ramirez, Bruna Sabatke, Maria Alice Ferreira Nunes, Jordana Dinorá de Lima, Izadora Volpato Rossi, Graciela Evans Ramirez

Publikováno v: Biochemistry and Molecular Biology Education

Active teaching methodologies have been placed as a hope for changing education at different levels, transiting from passive lecture-centered to student-centered learning. With the health measures of social distance, the COVID-19 pandemic forced a st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8563b4196897d790a9e82cc50ecd0203
https://doi.org/10.1002/bmb.21574

Can curcumin supplementation reduce plasma levels of gut-derived uremic toxins in hemodialysis patients? A pilot randomized, double-blind, controlled study

Autor: Lia S. Nakao, Roberta Salarolli, Laís de Souza Gouveia Moreira, Livia Alvarenga, Ludmila F M F Cardozo, Denis Fouque, Jordana Dinorá de Lima, Denise Mafra, Silvia D. Rodrigues, Karla Thaís Resende Teixeira

Publikováno v: International Urology and Nephrology
International Urology and Nephrology, Springer Verlag, 2021, 53 (6), pp.1231-1238. ⟨10.1007/s11255-020-02760-z⟩

International audience; BACKGROUND: Gut dysbiosis is common in patients with chronic kidney disease (CKD) and is closely related to inflammatory processes. Some nutritional strategies, such as bioactive compounds present in curcumin, have been propos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adc41870e9a19a443c941de3f9af9e04
https://www.hal.inserm.fr/inserm-03274435

Effect of Unripe Banana Flour on Gut-Derived Uremic Toxins in Individuals Undergoing Peritoneal Dialysis: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial

Autor: Maria Aparecida Dalboni, Lia S. Nakao, Fabiana Andréa Hoffmann Sardá, Natalia Barros Ferreira Pereira, Laila Santos de Andrade, Renata Rodrigues Teixeira, Jordana Dinorá de Lima, Silvia D. Rodrigues, Danilo Takashi Aoike, Lilian Cuppari

Publikováno v: Nutrients
Volume 13
Issue 2
Nutrients, Vol 13, Iss 646, p 646 (2021)

In chronic kidney disease (CKD), the accumulation of gut-derived metabolites, such as indoxyl sulfate (IS), p-cresyl sulfate (pCS), and indole 3-acetic acid (IAA), has been associated with the burden of the disease. In this context, prebiotics emerge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49ad38b1b2b679c667be5eaf942f5d9a
https://doi.org/10.3390/nu13020646

Genetic and Epigenetic Regulation of the Innate Immune Response to Gout.

Autor: de Lima, Jordana Dinorá¹ (AUTHOR), de Paula, André Guilherme Portela¹ (AUTHOR), Yuasa, Bruna Sadae¹ (AUTHOR), de Souza Smanioto, Caio Cesar¹ (AUTHOR), da Cruz Silva, Maria Clara¹ (AUTHOR), dos Santos, Priscila Ianzen² (AUTHOR), Prado, Karin Braun³ (AUTHOR), Winter Boldt, Angelica Beate^2,3 (AUTHOR), Braga, Tárcio Teodoro^1,4 (AUTHOR) tarcio.braga@ufpr.br

Publikováno v: Immunological Investigations. Apr2023, Vol. 52 Issue 3, p364-397. 34p.