Vaccine antibodies against a synthetic epidermal growth factor variant enhance the antitumor effects of inhibitors targeting the MAPK/ERK and PI3K/Akt pathways.

Autor: García-Roman S; Laboratory of Oncology/Pangaea Oncology S.L., Dexeus University Hospital, C/ Sabino Arana 5, Barcelona 08023, Spain., Garzón-Ibáñez M; Laboratory of Oncology/Pangaea Oncology S.L., Dexeus University Hospital, C/ Sabino Arana 5, Barcelona 08023, Spain., Bertrán-Alamillo J; Laboratory of Oncology/Pangaea Oncology S.L., Dexeus University Hospital, C/ Sabino Arana 5, Barcelona 08023, Spain., Jordana-Ariza N; Laboratory of Oncology/Pangaea Oncology S.L., Dexeus University Hospital, C/ Sabino Arana 5, Barcelona 08023, Spain., Giménez-Capitán A; Laboratory of Oncology/Pangaea Oncology S.L., Dexeus University Hospital, C/ Sabino Arana 5, Barcelona 08023, Spain., García-Peláez B; Laboratory of Oncology/Pangaea Oncology S.L., Dexeus University Hospital, C/ Sabino Arana 5, Barcelona 08023, Spain., Vives-Usano M; Laboratory of Oncology/Pangaea Oncology S.L., Dexeus University Hospital, C/ Sabino Arana 5, Barcelona 08023, Spain., Codony-Servat J; Laboratory of Oncology/Pangaea Oncology S.L., Dexeus University Hospital, C/ Sabino Arana 5, Barcelona 08023, Spain., d'Hondt E; IN3BIO Europe ltd, Aberdeen, UK., Rosell R; Instituto Oncológico Dr. Rosell (IOR), Dexeus University Hospital, Barcelona, Spain; Catalan Institute of Oncology and Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol, Badalona, Spain., Molina-Vila MÁ; Laboratory of Oncology/Pangaea Oncology S.L., Dexeus University Hospital, C/ Sabino Arana 5, Barcelona 08023, Spain. Electronic address: mamolina@panoncology.com.

Publikováno v: Translational oncology [Transl Oncol] 2024 Feb; Vol. 40, pp. 101878. Date of Electronic Publication: 2024 Jan 06.

The EPICAL trial, a phase Ib study combining first line afatinib with anti-EGF vaccination in EGFR-mutant metastatic NSCLC

Autor: Rodríguez-Abreu, D., Cobo, M., García-Román, S., Viteri-Ramírez, S., Jordana-Ariza, N., García-Peláez, B., Reguart, N., Aguilar, A., Codony-Servat, J., Drozdowskyj, A., Molina-Vila, M.A., d'Hondt, E., Rosell, R.

Publikováno v: In Lung Cancer February 2022 164:8-13

Evolution and Clinical Impact of EGFR Mutations in Circulating Free DNA in the BELIEF Trial

Autor: Molina-Vila, M.-A. Stahel, R.A. Dafni, U. Jordana-Ariza, N. Balada-Bel, A. Garzón-Ibáñez, M. García-Peláez, B. Mayo-de-las-Casas, C. Felip, E. Curioni Fontecedro, A. Gautschi, O. Peters, S. Massutí, B. Palmero, R. Ponce Aix, S. Carcereny, E. Früh, M. Pless, M. Popat, S. Cuffe, S. Bidoli, P. Kammler, R. Roschitzki-Voser, H. Tsourti, Z. Karachaliou, N. Rosell, R.

Introduction: Longitudinal evaluation of mutations in blood samples was a prespecified secondary objective in the BELIEF trial of erlotinib and bevacizumab in advanced EGFR-positive NSCLC. Here, we report the testing results and explore the correlati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::a086afd5b5e10432a3da1ab7c157668f
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3104717

Effect of Osimertinib on CTCs and ctDNA in EGFR Mutant Non-Small Cell Lung Cancer Patients: The Prognostic Relevance of Liquid Biopsy.

Autor: Kallergi G; Department of Biology, Division of Genetics, Cell and Developmental Biology, University of Patras, 26500 Patras, Greece., Kontopodis E; Department of Medical Oncology, 'Venizelio-Pananio' General Hospital of Heraklion, 71500 Heraklion, Greece., Ntzifa A; Analysis of Circulating Tumor Cells Lab, Department of Chemistry, University of Athens, 15772 Athens, Greece.; Lab of Analytical Chemistry, Department of Chemistry, University of Athens, 15772 Athens, Greece., Jordana-Ariza N; Laboratory of Oncology, Pangaea Oncology, Quiron Dexeus University Hospital, 08028 Barcelona, Spain., Karachaliou N; Laboratory of Oncology, Pangaea Oncology, Quiron Dexeus University Hospital, 08028 Barcelona, Spain., Pantazaka E; Department of Biology, Division of Genetics, Cell and Developmental Biology, University of Patras, 26500 Patras, Greece., Charalambous HA; Oncology Center of Bank of Cyprus, Department of Medical Oncology, Nicosia 2012, Cyprus., Psyrri A; Medical Oncology Unit, 2nd Department of Internal Medicine, 'ATTIKON' General Hospital of Athens, 12462 Athens, Greece., Tsaroucha E; 7th Department of Pulmonary Diseases, 'SOTIRIA' General Hospital of Athens, 11527 Athens, Greece., Boukovinas I; Department of Medical Oncology, BIOCLINIKI Hospital, 11524 Thessaloniki, Greece., Koumarianou A; Hematology-Oncology Unit, Fourth Department of Internal Medicine, Attikon Hospital, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece., Hatzidaki D; Hellenic Oncology Research Group (HORG), 1st Department of Medical Oncology, Metropolitan General Hospital, 15562 Athens, Greece., Lianidou E; Analysis of Circulating Tumor Cells Lab, Department of Chemistry, University of Athens, 15772 Athens, Greece.; Lab of Analytical Chemistry, Department of Chemistry, University of Athens, 15772 Athens, Greece., Georgoulias V; Hellenic Oncology Research Group (HORG), 1st Department of Medical Oncology, Metropolitan General Hospital, 15562 Athens, Greece., Rosell R; Laboratory of Oncology, Pangaea Oncology, Quiron Dexeus University Hospital, 08028 Barcelona, Spain., Kotsakis A; Department of Medical Oncology, University General Hospital of Larissa, Mezourlo, 41500 Larissa, Greece.

Publikováno v: Cancers [Cancers (Basel)] 2022 Mar 19; Vol. 14 (6). Date of Electronic Publication: 2022 Mar 19.

P59.03 Comparison of Two RNA-Based Platforms for Detection of Fusions and Met Splicing Variant in Non Small Cell Lung Cancer Samples

Autor: García Peláez, B., Gimenez-Capitán, A., Vives Usano, M., Roman, R., Garzón Ibañez, M., Aguado Esteban, C., Rodríguez, S., Aldeguer, E., Jordana Ariza, N., Viteri, S., Aguilar-Hernández, A., Moya, I., Cabrera, C., Catalán, M., Gonzalez-Cao, M., García Román, S., Bertrán- Alamillo, J., Garcia-Casabal, F., Rosell, R., Molina, M., Mayo-De-Las-Casas, C.

Publikováno v: In Journal of Thoracic Oncology October 2021 16(10) Supplement:S1147-S1147