Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jordan Whitt"'
Autor:
Emily M. Eshleman, Tzu-Yu Shao, Vivienne Woo, Taylor Rice, Laura Engleman, Bailey J. Didriksen, Jordan Whitt, David B. Haslam, Sing Sing Way, Theresa Alenghat
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 4 (2023)
Aberrant immune responses to resident microbes promote inflammatory bowel disease and other chronic inflammatory conditions. However, how microbiota-specific immunity is controlled in mucosal tissues remains poorly understood. Here, we found that mic
Externí odkaz:
https://doaj.org/article/9020d0eccbb047c8940d96aee38825dc
Autor:
Seika Hashimoto-Hill, Luisa Colapietro, Vivienne Woo, Simona Antonacci, Jordan Whitt, Laura Engleman, Theresa Alenghat
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Although diet has long been associated with susceptibility to infection, the dietary components that regulate host defense remain poorly understood. Here, we demonstrate that consuming rice bran decreases susceptibility to intestinal infection with C
Externí odkaz:
https://doaj.org/article/8f1a54b9d827436abf95d0b3e5bbc7bc
Autor:
Nazanin Navabi, Jordan Whitt, Shu-en Wu, Vivienne Woo, Jessica Moncivaiz, Michael B. Jordan, Bruce A. Vallance, Sing Sing Way, Theresa Alenghat
Publikováno v:
Cell Reports, Vol 19, Iss 6, Pp 1165-1175 (2017)
Mucosal tissues are constantly in direct contact with diverse beneficial and pathogenic microbes, highlighting the need for orchestrating complex microbial signals to sustain effective host defense. Here, we show an essential role for intestinal epit
Externí odkaz:
https://doaj.org/article/cf9c6531f7a7493785cf44c32e72b6ad
Autor:
Vivienne Woo, Emily M. Eshleman, Taylor Rice, Jordan Whitt, Bruce A. Vallance, Theresa Alenghat
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Numerous bacterial pathogens infect the mammalian host by initially associating with epithelial cells that line the intestinal lumen. Recent work has revealed that commensal bacteria that reside in the intestine promote defense against pathogenic inf
Externí odkaz:
https://doaj.org/article/5451ad4930104bd890fafedc3c865624
Autor:
Rebekah Karns, Lee A. Denson, Laura Engleman, Theresa Alenghat, Jordan Whitt, Seika Hashimoto-Hill, David B. Haslam, Vivienne Woo, Emily M. Eshleman, Shu-en Wu
Publikováno v:
Nature. 586:108-112
The coevolution of mammalian hosts and their beneficial commensal microbes has led to development of symbiotic host–microbiota relationships1. Epigenetic machinery permits mammalian cells to integrate environmental signals2; however, how these path
Autor:
Emily M. Eshleman, Tzu-Yu Shao, Vivienne Woo, Taylor Rice, Jordan Whitt, Laura Engleman, Sing Sing Way, Theresa Alenghat
Aberrant immune responses to resident microbes promote inflammatory bowel disease and other chronic inflammatory conditions. However, how microbiota-specific immunity is controlled in mucosal tissues remains poorly understood. Here, we find that mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e410772867cb1115cdb606e313837bef
https://doi.org/10.1101/2022.01.01.473735
https://doi.org/10.1101/2022.01.01.473735
Autor:
Emily M Eshleman, Tzu-Yu Shao, Vivienne Woo, Taylor Rice, Jordan Whitt, Laura Engleman, Sing Sing Way, Theresa Alenghat
Publikováno v:
The Journal of Immunology. 208:115.03-115.03
The intestinal microbiota is essential for instructing the host immune system, however, dysregulated immune responses to resident commensal microbes can promote pathologic inflammation. Despite this relationship, the mechanisms regulating tissue-intr
Autor:
Jordan Whitt, Laura Engleman, Shu-en Wu, Taylor Rice, Seika Hashimoto-Hill, Vivienne Woo, Rebekah Karns, Bruce A. Vallance, Theresa Alenghat, Emily M. Eshleman
SummaryInteractions between the microbiota and mammalian host are essential for effective defense against pathogenic infection; however, the microbial-derived cues that mediate this beneficial relationship remain unclear. Here, we find that the intes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f4265e6d40017324fcab2c35a742ca3
https://doi.org/10.1101/2021.01.27.428280
https://doi.org/10.1101/2021.01.27.428280
Autor:
Emily M. Eshleman, Shu-en Wu, David B. Haslam, Vivienne Woo, Laura Engleman, Seika Hashimoto-Hill, Bruce A. Vallance, Theresa Alenghat, Jordan Whitt, Taylor Rice, Joseph E. Qualls, Rebekah Karns
Publikováno v:
Cell Host Microbe
Summary Interactions between the microbiota and mammalian host are essential for defense against infection, but the microbial-derived cues that mediate this relationship remain unclear. Here, we find that intestinal epithelial cell (IEC)-associated c
Autor:
Patrick Tso, Theresa Alenghat, Patrick Lee, Vivienne Woo, Yael Haberman, Jessica Moncivaiz, Jordan Whitt, Lee A. Denson
Publikováno v:
Gastroenterology. 155:501-513
Background & Aims Intestinal microbiota modulate metabolism and associate closely with epithelial cells in the intestine. In intestinal epithelial cells (IECs), histone deacetylase 3 (HDAC3) integrates microbiota-derived signals to control intestinal