Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jordan W. Conway"'
Autor:
Jordan W. Conway, Jorja Braden, James S. Wilmott, Richard A. Scolyer, Georgina V. Long, Inês Pires da Silva
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Immunotherapy, particularly immune checkpoint inhibitors, have become widely used in various settings across many different cancer types in recent years. Whilst patients are often treated on the basis of the primary cancer type and clinical stage, re
Externí odkaz:
https://doaj.org/article/32d8252a962146309d6a7441b43f2f43
Autor:
Zarwa Yaseen, Tuba N. Gide, Jordan W. Conway, Alison J. Potter, Camelia Quek, Angela M. Hong, Georgina V. Long, Richard A. Scolyer, James S. Wilmott
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Multiplex immunofluorescence staining enables the simultaneous detection of multiple immune markers in a single tissue section, and is a useful tool for the identification of specific cell populations within the tumour microenvironment. However, this
Externí odkaz:
https://doaj.org/article/981eb8190d6b4c0d884849cb1fb0858b
Autor:
Andrew J Colebatch, John F Thompson, Serigne Lo, Ines Pires da Silva, Georgina V Long, Richard A Scolyer, Kazi J Nahar, Tasnia Ahmed, Umaimainthan Palendira, Alexander M Menzies, Jordan W Conway, Matteo S Carlino, Ismael A Vergara, James S Wilmott, Grace Heloise Attrill, Carina N Owen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/bc42aa6825a44fdb8db135c1150e97e4
Autor:
Hansol Lee, Angela L. Ferguson, Camelia Quek, Ismael A. Vergara, Ines Pires daSilva, Ruth Allen, Tuba Nur Gide, Jordan W. Conway, Lambros T. Koufariotis, Nicholas K. Hayward, Nicola Waddell, Matteo S. Carlino, Alexander M. Menzies, Robyn P.M. Saw, Elena Shklovskaya, Helen Rizos, Serigne Lo, Richard A. Scolyer, Georgina V. Long, Umaimainthan Palendira, James S. Wilmott
Publikováno v:
Clinical Cancer Research. :OF1-OF12
Purpose: This study characterizes intratumoral macrophage populations within baseline melanoma biopsies from patients with advanced melanoma who received either anti-PD-1 monotherapy or a combination with anti-CTLA-4. Particularly, FcγRIIIa (CD16)-e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d784ce8b1109474c90649f699faeba2
https://doi.org/10.1158/1078-0432.ccr-22-2657
https://doi.org/10.1158/1078-0432.ccr-22-2657
Autor:
James S. Wilmott, Umaimainthan Palendira, Georgina V. Long, Richard A. Scolyer, Serigne Lo, Helen Rizos, Elena Shklovskaya, Robyn P.M. Saw, Alexander M. Menzies, Matteo S. Carlino, Nicola Waddell, Nicholas K. Hayward, Lambros T. Koufariotis, Jordan W. Conway, Tuba Nur Gide, Ruth Allen, Ines Pires daSilva, Ismael A. Vergara, Camelia Quek, Angela L. Ferguson, Hansol Lee
C1Q and PD-1 expression on CD16+ macrophages in on treatment biopsies of melanoma patients treated with PD-1 or PD-1+CTLA-4 ICB. Dynamics between pretreatment and early-during treatment biopsies on (a) CD16+ macrophages as a proportion of all macroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14612cae31cb766578780e949a0d035e
https://doi.org/10.1158/1078-0432.22490758.v1
https://doi.org/10.1158/1078-0432.22490758.v1
Autor:
James S. Wilmott, Umaimainthan Palendira, Georgina V. Long, Richard A. Scolyer, Serigne Lo, Helen Rizos, Elena Shklovskaya, Robyn P.M. Saw, Alexander M. Menzies, Matteo S. Carlino, Nicola Waddell, Nicholas K. Hayward, Lambros T. Koufariotis, Jordan W. Conway, Tuba Nur Gide, Ruth Allen, Ines Pires daSilva, Ismael A. Vergara, Camelia Quek, Angela L. Ferguson, Hansol Lee
Differential expression analysis gene list of FACS sorted CD16+ compared to CD16- macrophages from human melanoma dissociates.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6232323a8928f6748dc05f4042e2cbe0
https://doi.org/10.1158/1078-0432.22490749
https://doi.org/10.1158/1078-0432.22490749
Autor:
James S. Wilmott, Umaimainthan Palendira, Georgina V. Long, Richard A. Scolyer, Serigne Lo, Helen Rizos, Elena Shklovskaya, Robyn P.M. Saw, Alexander M. Menzies, Matteo S. Carlino, Nicola Waddell, Nicholas K. Hayward, Lambros T. Koufariotis, Jordan W. Conway, Tuba Nur Gide, Ruth Allen, Ines Pires daSilva, Ismael A. Vergara, Camelia Quek, Angela L. Ferguson, Hansol Lee
Purpose:This study characterizes intratumoral macrophage populations within baseline melanoma biopsies from patients with advanced melanoma who received either anti-PD-1 monotherapy or a combination with anti-CTLA-4. Particularly, FcγRIIIa (CD16)-ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c6f2199d79af940132b22b50fc8fbba
https://doi.org/10.1158/1078-0432.c.6533212.v1
https://doi.org/10.1158/1078-0432.c.6533212.v1
Autor:
Jordan W. Conway, Felix Marsh-Wakefield, Kazi J. Nahar, Serigne N. Lo, Ismael A. Vergara, Tuba N. Gide, Grace H. Attrill, Jorja Braden, Matteo S. Carlino, Robyn P. Saw, John F. Thompson, Andrew J. Spillane, Kerwin F. Shannon, Brindha Shivalingam, Alexander M. Menzies, Umaimainthan Palendira, James S. Wilmott, Georgina V. Long, Richard A. Scolyer, Ines Pires Da Silva
Publikováno v:
Cancer Research. 83:81-81
Purpose Patients with melanoma liver metastases have significantly reduced overall response and survival when treated with immune checkpoint inhibitors (ICI) compared to those without liver metastases. Melanoma liver metastases are less likely to res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::236b4b1b9576510d27ef7aeb3e3c572b
https://doi.org/10.1158/1538-7445.am2023-81
https://doi.org/10.1158/1538-7445.am2023-81
Autor:
Jordan W Conway, Robert V Rawson, Serigne Lo, Tasnia Ahmed, Ismael A Vergara, Tuba N Gide, Grace Heloise Attrill, Matteo S Carlino, Robyn P M Saw, John F Thompson, Andrew J Spillane, Kerwin F Shannon, Brindha Shivalingam, Alexander Maxwell Menzies, James S Wilmott, Georgina V Long, Richard A Scolyer, Ines Pires da Silva
Publikováno v:
Journal for ImmunoTherapy of Cancer. 10:e004884
BackgroundThe liver is a known site of resistance to immunotherapy and the presence of liver metastases is associated with shorter progression-free and overall survival (OS) in melanoma, while lung metastases have been associated with a more favorabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0513a412f6148d1d4bb01c88a2093717
https://doi.org/10.1136/jitc-2022-004884
https://doi.org/10.1136/jitc-2022-004884
Autor:
Grace Heloise Attrill, Teresa A. Bailey, Trina Lum, Jordan W. Conway, Georgina V. Long, James S. Wilmott, Richard A. Scolyer
Publikováno v:
Cancer Research. 82:2221-2221
Surgical excision with histologically clear margins results in cure of most melanoma patients. Involvement of the margins is associated with tumour recurrence and adverse outcomes. Determining whether or not the histological margins are involved by m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4573d4b1531a9b59676a59ede9aa5a0b
https://doi.org/10.1158/1538-7445.am2022-2221
https://doi.org/10.1158/1538-7445.am2022-2221