Zobrazeno 1 - 10 of 23 pro vyhledávání: '"Jordan W. Conway"'
1
Akademický článek
The effect of organ-specific tumor microenvironments on response patterns to immunotherapy
Autor: Jordan W. Conway, Jorja Braden, James S. Wilmott, Richard A. Scolyer, Georgina V. Long, Inês Pires da Silva
Publikováno v: Frontiers in Immunology, Vol 13 (2022)
Immunotherapy, particularly immune checkpoint inhibitors, have become widely used in various settings across many different cancer types in recent years. Whilst patients are often treated on the basis of the primary cancer type and clinical stage, re
Externí odkaz: https://doaj.org/article/32d8252a962146309d6a7441b43f2f43
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2
Akademický článek
Unveiling the tumor immune microenvironment of organ-specific melanoma metastatic sites
Autor: John F Thompson, Serigne Lo, Ines Pires da Silva, Georgina V Long, Richard A Scolyer, Andrew J Spillane, Robert V Rawson, Tasnia Ahmed, Jordan W Conway, Matteo S Carlino, Ismael A Vergara, James S Wilmott, Grace Heloise Attrill, Tuba N Gide, Robyn P M Saw, Kerwin F Shannon, Brindha Shivalingam, Alexander Maxwell Menzies
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 10, Iss 9 (2022)
Background The liver is a known site of resistance to immunotherapy and the presence of liver metastases is associated with shorter progression-free and overall survival (OS) in melanoma, while lung metastases have been associated with a more favorab
Externí odkaz: https://doaj.org/article/c656c5775fc74e02a519bcf5c3149e12
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4
Akademický článek
Validation of an Accurate Automated Multiplex Immunofluorescence Method for Immuno-Profiling Melanoma
Autor: Zarwa Yaseen, Tuba N. Gide, Jordan W. Conway, Alison J. Potter, Camelia Quek, Angela M. Hong, Georgina V. Long, Richard A. Scolyer, James S. Wilmott
Publikováno v: Frontiers in Molecular Biosciences, Vol 9 (2022)
Multiplex immunofluorescence staining enables the simultaneous detection of multiple immune markers in a single tissue section, and is a useful tool for the identification of specific cell populations within the tumour microenvironment. However, this
Externí odkaz: https://doaj.org/article/981eb8190d6b4c0d884849cb1fb0858b
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6
Akademický článek
Comprehensive analysis of cutaneous and uveal melanoma liver metastases
Autor: Annegien Broeks, Sarah Warren, Pia Kvistborg, Richard A Scolyer, Esmee P Hoefsmit, Elisa A Rozeman, Trieu My Van, Petros Dimitriadis, Oscar Krijgsman, Jordan W Conway, Jacqueline E van der Wal, Steven L C Ketelaars, Kaspar Bresser, Ron M Kerkhoven, Jason W Reeves, Ellen W Kapiteijn, Daniel S Peeper, Ton N M Schumacher
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background The profound disparity in response to immune checkpoint blockade (ICB) by cutaneous melanoma (CM) and uveal melanoma (UM) patients is not well understood. Therefore, we characterized metastases of CM and UM from the same metastatic site (l
Externí odkaz: https://doaj.org/article/57566697358f40ef905dd40c8195aef6
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