Zobrazeno 1 - 10
of 589
pro vyhledávání: '"Jordan W, Smoller"'
Autor:
Giovanni Civieri, MD, Shady Abohashem, MD, Simran S. Grewal, DO, Wesam Aldosoky, MD, Iqra Qamar, MD, Erin Hanlon, BS, Karmel W. Choi, PhD, Lisa M. Shin, PhD, Rachel P. Rosovsky, MD, MPH, Sandeep Chandra Bollepalli, PhD, Hui Chong Lau, Antonis Armoundas, PhD, Antonia V. Seligowski, PhD, Sarah M. Turgeon, PhD, Roger K. Pitman, MD, Francesco Tona, MD, PhD, Jason H. Wasfy, MD, MPhil, Jordan W. Smoller, MD, ScD, Sabino Iliceto, MD, Jill Goldstein, PhD, MPH, Catherine Gebhard, MD, PhD, Michael T. Osborne, MD, Ahmed Tawakol, MD
Publikováno v:
JACC: Advances, Vol 3, Iss 9, Pp 101208- (2024)
Background: Prior studies have incompletely assessed whether the development of cardiometabolic risk factors (CVDRF) (hypertension, hyperlipidemia, and diabetes mellitus) mediates the association between anxiety and depression (anxiety/depression) an
Externí odkaz:
https://doaj.org/article/acba6f594d3d4279a421a77feae50b76
Autor:
Colin G. Walsh, Michael A. Ripperger, Yirui Hu, Yi-han Sheu, Hyunjoon Lee, Drew Wilimitis, Amanda B. Zheutlin, Daniel Rocha, Karmel W. Choi, Victor M. Castro, H. Lester Kirchner, Christopher F. Chabris, Lea K. Davis, Jordan W. Smoller
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Bipolar disorder is a leading contributor to disability, premature mortality, and suicide. Early identification of risk for bipolar disorder using generalizable predictive models trained on diverse cohorts around the United States could impr
Externí odkaz:
https://doaj.org/article/94f1cfffc2144cf09173606b3f636a0f
Autor:
Kate H Bentley, Emily M Madsen, Eugene Song, Yu Zhou, Victor Castro, Hyunjoon Lee, Younga H Lee, Jordan W Smoller
Publikováno v:
JMIR Formative Research, Vol 8, p e46364 (2024)
BackgroundPrior suicide attempts are a relatively strong risk factor for future suicide attempts. There is growing interest in using longitudinal electronic health record (EHR) data to derive statistical risk prediction models for future suicide atte
Externí odkaz:
https://doaj.org/article/459c9f254fec45bbb9ab2a20cae30586
Autor:
Xueyao Wu, Wenqiang Zhang, Xunying Zhao, Li Zhang, Minghan Xu, Yu Hao, Jinyu Xiao, Ben Zhang, Jiayuan Li, Peter Kraft, Jordan W. Smoller, Xia Jiang
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Background Both depression and breast cancer (BC) contribute to a substantial global burden of morbidity and mortality among women, and previous studies have observed a potential depression-BC link. We aimed to comprehensively characterize t
Externí odkaz:
https://doaj.org/article/43c629c97a7a4fa2a3f7d79e19c4343d
Publikováno v:
npj Digital Medicine, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Antidepressant selection is largely a trial-and-error process. We used electronic health record (EHR) data and artificial intelligence (AI) to predict response to four antidepressants classes (SSRI, SNRI, bupropion, and mirtazapine) 4 to 12
Externí odkaz:
https://doaj.org/article/139df4b556e740c181ab8de98d1e4cfa
Autor:
Jakob Seidlitz, Travis T. Mallard, Jacob W. Vogel, Younga H. Lee, Varun Warrier, Gareth Ball, Oskar Hansson, Leanna M. Hernandez, Ayan S. Mandal, Konrad Wagstyl, Michael V. Lombardo, Eric Courchesne, Joseph T. Glessner, Theodore D. Satterthwaite, Richard A.I. Bethlehem, Joshua D. Bernstock, Shinya Tasaki, Bernard Ng, Chris Gaiteri, Jordan W. Smoller, Tian Ge, Raquel E. Gur, Michael J. Gandal, Aaron F. Alexander-Bloch
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113439- (2023)
Summary: Human brain size changes dynamically through early development, peaks in adolescence, and varies up to 2-fold among adults. However, the molecular genetic underpinnings of interindividual variation in brain size remain unknown. Here, we leve
Externí odkaz:
https://doaj.org/article/64ee1401f7fc44968f6a52b884af8318
Autor:
Andrew D. Grotzinger, Travis T. Mallard, Zhaowen Liu, Jakob Seidlitz, Tian Ge, Jordan W. Smoller
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
The current study identifies five genomic subclusters of brain regions for cortical thickness and surface area characterized by high levels of shared genetic signal. These subclusters map onto biological and functional parcellations of the cortex.
Externí odkaz:
https://doaj.org/article/558351e4e4a34c35ad3e76b038aa1876
Autor:
Francesca L. Beaudoin, Xinming An, Archana Basu, Yinyao Ji, Mochuan Liu, Ronald C. Kessler, Robert F. Doughtery, Donglin Zeng, Kenneth A. Bollen, Stacey L. House, Jennifer S. Stevens, Thomas C. Neylan, Gari D. Clifford, Tanja Jovanovic, Sarah D. Linnstaedt, Laura T. Germine, Scott L. Rauch, John P. Haran, Alan B. Storrow, Christopher Lewandowski, Paul I. Musey, Phyllis L. Hendry, Sophia Sheikh, Christopher W. Jones, Brittany E. Punches, Michael C. Kurz, Robert A. Swor, Vishnu P. Murty, Meghan E. McGrath, Lauren A. Hudak, Jose L. Pascual, Elizabeth M. Datner, Anna M. Chang, Claire Pearson, David A. Peak, Roland C. Merchant, Robert M. Domeier, Niels K. Rathlev, Brian J. O’ Neil, Paulina Sergot, Leon D. Sanchez, Steven E. Bruce, Justin T. Baker, Jutta Joormann, Mark W. Miller, Robert H. Pietrzak, Deanna M. Barch, Diego A. Pizzagalli, John F. Sheridan, Jordan W. Smoller, Steven E. Harte, James M. Elliott, Karestan C. Koenen, Kerry J. Ressler, Samuel A. McLean
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The authors sought to characterize adverse posttraumatic neuropsychiatric sequelae (APNS) symptom trajectories across ten symptom domains (pain, depression, sleep, nightmares, avoidance, re-experiencing, anxiety, hyperarousal, somatic, and m
Externí odkaz:
https://doaj.org/article/510c0dddcb9f404fb719cf4b5ffda57e
Autor:
Anna C. F. Lewis, Emma F. Perez, Anya E. R. Prince, Hana R. Flaxman, Lizbeth Gomez, Deanna G. Brockman, Paulette D. Chandler, Benjamin J. Kerman, Matthew S. Lebo, Jordan W. Smoller, Scott T. Weiss, Carrie L. Blout Zawatksy, James B. Meigs, Robert C. Green, Jason L. Vassy, Elizabeth W. Karlson
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-16 (2022)
Abstract Background Polygenic risk scores (PRS), which offer information about genomic risk for common diseases, have been proposed for clinical implementation. The ways in which PRS information may influence a patient’s health trajectory depend on
Externí odkaz:
https://doaj.org/article/b19f80c5d7664fe791e51eb803730865
Autor:
Yu-Han H. Hsu, Greta Pintacuda, Ruize Liu, Eugeniu Nacu, April Kim, Kalliopi Tsafou, Natalie Petrossian, William Crotty, Jung Min Suh, Jackson Riseman, Jacqueline M. Martin, Julia C. Biagini, Daya Mena, Joshua K.T. Ching, Edyta Malolepsza, Taibo Li, Tarjinder Singh, Tian Ge, Shawn B. Egri, Benjamin Tanenbaum, Caroline R. Stanclift, Annie M. Apffel, Steven A. Carr, Monica Schenone, Jake Jaffe, Nadine Fornelos, Hailiang Huang, Kevin C. Eggan, Kasper Lage, Stephan Ripke, Benjamin M. Neale, Aiden Corvin, James T.R. Walters, Kai-How Farh, Peter A. Holmans, Phil Lee, Brendan Bulik-Sullivan, David A. Collier, Tune H. Pers, Ingrid Agartz, Esben Agerbo, Margot Albus, Madeline Alexander, Farooq Amin, Silviu A. Bacanu, Martin Begemann, Richard A. Belliveau, Jr., Judit Bene, Sarah E. Bergen, Elizabeth Bevilacqua, Tim B. Bigdeli, Donald W. Black, Richard Bruggeman, Nancy G. Buccola, Randy L. Buckner, William Byerley, Wiepke Cahn, Guiqing Cai, Dominique Campion, Rita M. Cantor, Vaughan J. Carr, Noa Carrera, Stanley V. Catts, Kimberley D. Chambert, Raymond C.K. Chan, Ronald Y.L. Chan, Eric Y.H. Chen, Wei Cheng, Eric FC. Cheung, Siow Ann Chong, C. Robert Cloninger, David Cohen, Nadine Cohen, Paul Cormican, Nick Craddock, James J. Crowley, David Curtis, Michael Davidson, Kenneth L. Davis, Franziska Degenhardt, Jurgen Del Favero, Ditte Demontis, Dimitris Dikeos, Timothy Dinan, Srdjan Djurovic, Gary Donohoe, Elodie Drapeau, Jubao Duan, Frank Dudbridge, Naser Durmishi, Peter Eichhammer, Johan Eriksson, Valentina Escott-Price, Laurent Essioux, Ayman H. Fanous, Martilias S. Farrell, Josef Frank, Lude Franke, Robert Freedman, Nelson B. Freimer, Marion Friedl, Joseph I. Friedman, Menachem Fromer, Giulio Genovese, Lyudmila Georgieva, Ina Giegling, Paola Giusti-Rodríguez, Stephanie Godard, Jacqueline I. Goldstein, Vera Golimbet, Srihari Gopal, Jacob Gratten, Lieuwe de Haan, Christian Hammer, Marian L. Hamshere, Mark Hansen, Thomas Hansen, Vahram Haroutunian, Annette M. Hartmann, Frans A. Henskens, Stefan Herms, Joel N. Hirschhorn, Per Hoffmann, Andrea Hofman, Mads V. Hollegaard, David M. Hougaard, Masashi Ikeda, Inge Joa, Antonio Julià, René S. Kahn, Luba Kalaydjieva, Sena Karachanak-Yankova, Juha Karjalainen, David Kavanagh, Matthew C. Keller, James L. Kennedy, Andrey Khrunin, Yunjung Kim, Janis Klovins, James A. Knowles, Bettina Konte, Vaidutis Kucinskas, Zita Ausrele Kucinskiene, Hana Kuzelova-Ptackova, Anna K. Kähler, Claudine Laurent, Jimmy Lee, S. Hong Lee, Sophie E. Legge, Bernard Lerer, Miaoxin Li, Tao Li, Kung-Yee Liang, Jeffrey Lieberman, Svetlana Limborska, Carmel M. Loughland, Jan Lubinski, Jouko Lönnqvist, Milan Macek, Patrik K.E. Magnusson, Brion S. Maher, Wolfgang Maier, Jacques Mallet, Sara Marsal, Manuel Mattheisen, Morten Mattingsdal, Robert W. McCarley, Colm McDonald, Andrew M. McIntosh, Sandra Meier, Carin J. Meijer, Bela Melegh, Ingrid Melle, Raquelle I. Mesholam-Gately, Andres Metspalu, Patricia T. Michie, Lili Milani, Vihra Milanova, Younes Mokrab, Derek W. Morris, Ole Mors, Kieran C. Murphy, Robin M. Murray, Inez Myin-Germeys, Bertram Müller-Myhsok, Mari Nelis, Igor Nenadic, Deborah A. Nertney, Gerald Nestadt, Kristin K. Nicodemus, Liene Nikitina-Zake, Laura Nisenbaum, Annelie Nordin, Eadbhard O'Callaghan, Colm O'Dushlaine, F. Anthony O'Neill, Sang-Yun Oh, Ann Olincy, Line Olsen, Jim Van Os, Christos Pantelis, George N. Papadimitriou, Sergi Papiol, Elena Parkhomenko, Michele T. Pato, Tiina Paunio, Milica Pejovic-Milovancevic, Diana O. Perkins, Olli Pietiläinen, Jonathan Pimm, Andrew J. Pocklington, John Powell, Alkes Price, Ann E. Pulver, Shaun M. Purcell, Digby Quested, Henrik B. Rasmussen, Abraham Reichenberg, Mark A. Reimers, Alexander L. Richards, Joshua L. Roffman, Panos Roussos, Douglas M. Ruderfer, Veikko Salomaa, Alan R. Sanders, Ulrich Schall, Christian R. Schubert, Thomas G. Schulze, Sibylle G. Schwab, Edward M. Scolnick, Rodney J. Scott, Larry J. Seidman, Jianxin Shi, Engilbert Sigurdsson, Teimuraz Silagadze, Jeremy M. Silverman, Kang Sim, Petr Slominsky, Jordan W. Smoller, Hon-Cheong So, Chris C.A. Spencer, Eli A. Stahl, Hreinn Stefansson, Stacy Steinberg, Elisabeth Stogmann, Richard E. Straub, Eric Strengman, Jana Strohmaier, T Scott Stroup, Mythily Subramaniam, Jaana Suvisaari, Dragan M. Svrakic, Jin P. Szatkiewicz, Erik Söderman, Srinivas Thirumalai, Draga Toncheva, Sarah Tosato, Juha Veijola, John Waddington, Dermot Walsh, Dai Wang, Qiang Wang, Bradley T. Webb, Mark Weiser, Dieter B. Wildenauer, Nigel M. Williams, Stephanie Williams, Stephanie H. Witt, Aaron R. Wolen, Emily H.M. Wong, Brandon K. Wormley, Hualin Simon Xi, Clement C. Zai, Xuebin Zheng, Fritz Zimprich, Naomi R. Wray, Kari Stefansson, Peter M. Visscher, Rolf Adolfsson, Ole A. Andreassen, Douglas H.R. Blackwood, Elvira Bramon, Joseph D. Buxbaum, Anders D. Børglum, Sven Cichon, Ariel Darvasi, Enrico Domenici, Hannelore Ehrenreich, Tõnu Esko, Pablo V. Gejman, Michael Gill, Hugh Gurling, Christina M. Hultman, Nakao Iwata, Assen V. Jablensky, Erik G. Jönsson, Kenneth S. Kendler, George Kirov, Jo Knight, Todd Lencz, Douglas F. Levinson, Qingqin S. Li, Jianjun Liu, Anil K. Malhotra, Steven A. McCarroll, Andrew McQuillin, Jennifer L. Moran, Preben B. Mortensen, Bryan J. Mowry, Markus M. Nöthen, Roel A. Ophoff, Michael J. Owen, Aarno Palotie, Carlos N. Pato, Tracey L. Petryshen, Danielle Posthuma, Marcella Rietschel, Brien P. Riley, Dan Rujescu, Pak C. Sham, Pamela Sklar, David St Clair, Daniel R. Weinberger, Jens R. Wendland, Thomas Werge, Mark J. Daly, Patrick F. Sullivan, Michael C. O'Donovan, Shengying Qin, Akira Sawa, Rene Kahn, Kyung Sue Hong, Wenzhao Shi, Ming Tsuang, Masanari Itokawa, Gang Feng, Stephen J. Glatt, Xiancang Ma, Jinsong Tang, Yunfeng Ruan, Feng Zhu, Yasue Horiuchi, Byung Dae Lee, Eun-Jeong Joo, Woojae Myung, Kyooseob Ha, Hong-Hee Won, Ji Hyung Baek, Young Chul Chung, Sung-Wan Kim, Agung Kusumawardhani, Wei J. Chen, Hai-Gwo Hwu, Akitoyo Hishimoto, Ikuo Otsuka, Ichiro Sora, Tomoko Toyota, Takeo Yoshikawa, Hiroshi Kunugi, Kotaro Hattori, Sayuri Ishiwata, Shusuke Numata, Tetsuro Ohmori, Makoto Arai, Yuji Ozeki, Kumiko Fujii, Se Joo Kim, Heon-Jeong Lee, Yong Min Ahn, Se Hyun Kim, Kazufumi Akiyama, Kazutaka Shimoda, Makoto Kinoshita
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106701- (2023)
Summary: Genetics have nominated many schizophrenia risk genes and identified convergent signals between schizophrenia and neurodevelopmental disorders. However, functional interpretation of the nominated genes in the relevant brain cell types is oft
Externí odkaz:
https://doaj.org/article/49cc77d8d4ee4572b1f6ef76532d303e