Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jordan T. Bateman"'
Autor:
Jordan T Bateman, Erica S Levitt
Publikováno v:
eLife, Vol 12 (2023)
Opioids depress breathing by inhibition of interconnected respiratory nuclei in the pons and medulla. Mu opioid receptor (MOR) agonists directly hyperpolarize a population of neurons in the dorsolateral pons, particularly the Kölliker-Fuse (KF) nucl
Externí odkaz:
https://doaj.org/article/6dbf5c7b977745deae52b42048ee4135
Publikováno v:
Br J Pharmacol
Respiratory depression is the proximal cause of death in opioid overdose, yet the mechanisms underlying this potentially fatal outcome are not well understood. The goal of this review is to provide a comprehensive understanding of the pharmacological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63cc72c807d324088144be1d89936b64
https://doi.org/10.1111/bph.15580
https://doi.org/10.1111/bph.15580
Autor:
Jordan T. Bateman, Erica S. Levitt
Opioids depress breathing by inhibition of inter-connected respiratory nuclei in the pons and medulla. Mu opioid receptor (MOR) agonists directly hyperpolarize a population of neurons in the dorsolateral pons, particularly the Kölliker-Fuse (KF) nuc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ac4da907374020af7e23d7917a0557b
https://doi.org/10.1101/2022.06.24.497461
https://doi.org/10.1101/2022.06.24.497461
Autor:
Jordan T. Bateman, Erica S. Levitt
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4558e67f1650c8346ff25798184d95a8
https://doi.org/10.1096/fasebj.2022.36.s1.r2057
https://doi.org/10.1096/fasebj.2022.36.s1.r2057
Autor:
Sebastian N. Maletz, Brandon T. Reid, David M. Baekey, Jessica R. Whitaker-Fornek, Jordan T. Bateman, John M. Bissonnette, Erica S. Levitt
Rett syndrome (RTT) is an autism spectrum disorder caused by loss-of-function mutations in the methyl-CPG-binding protein 2 (Mecp2) gene. Frequent apneas and irregular breathing are prevalent in RTT, and also occur in rodent models of the disorder, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50e15ca7156b27d7f6c268eb412fed89
https://doi.org/10.1101/2022.04.13.488220
https://doi.org/10.1101/2022.04.13.488220
Autor:
Jordan T. Bateman, Erica S. Levitt
Publikováno v:
Am J Physiol Cell Physiol
Respiratory depression is a potentially fatal side effect of opioid analgesics and a major limitation to their use. G protein-biased opioid agonists have been proposed as “safer” analgesics with less respiratory depression. These agonists are bia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f821491712c2a1d0219460d7be8838ed
https://pubmed.ncbi.nlm.nih.gov/34469203
https://pubmed.ncbi.nlm.nih.gov/34469203
Publikováno v:
J Neurochem
The Kolliker-Fuse nucleus (KF) is a functionally distinct component of the parabrachial complex, located in the dorsolateral pons of mammals. The KF has a major role in respiration and upper airway control. A comprehensive understanding of the KF and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0fdd7cb85836d72ef2df79bceb1ea9
https://pubmed.ncbi.nlm.nih.gov/32396650
https://pubmed.ncbi.nlm.nih.gov/32396650
Autor:
Erica S. Levitt, Jordan T. Bateman
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46687d17d8eaceecd5b2ad4ff027f15a
https://doi.org/10.1096/fasebj.2019.33.1_supplement.663.3
https://doi.org/10.1096/fasebj.2019.33.1_supplement.663.3
Autor:
MacDonald J. Christie, Frank Schmiedel, Jordan T. Bateman, John T. Williams, Erica S. Levitt, Stefan Schulz, Andrea Kliewer, Setareh Sianati, Alexis Bailey
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications
Nature Communications
Opioid analgesics are powerful pain relievers; however, over time, pain control diminishes as analgesic tolerance develops. The molecular mechanisms initiating tolerance have remained unresolved to date. We have previously shown that desensitization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::903c7fefdcb5d99ab42f415f59f6647b
https://openaccess.sgul.ac.uk/id/eprint/110559/1/s41467-018-08162-1.pdf
https://openaccess.sgul.ac.uk/id/eprint/110559/1/s41467-018-08162-1.pdf
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e69eaf941daba5c9e7ffad9c96c8afa
https://doi.org/10.1096/fasebj.2020.34.s1.03540
https://doi.org/10.1096/fasebj.2020.34.s1.03540