Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Jordan T Shin"'
Autor:
Nelson W Chong, Andrea L Koekemoer, Samir Ounzain, Nilesh J Samani, Jordan T Shin, Stanley Y Shaw
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40966 (2012)
BackgroundSTARS (STriated muscle Activator of Rho Signaling) is a sarcomeric protein expressed early in cardiac development that acts as an acute stress sensor for pathological remodeling. However the role of STARS in cardiac development and function
Externí odkaz:
https://doaj.org/article/5ca74fa7ae754439ba213b105f25620f
Publikováno v:
Current opinion in organ transplantation. 24(5)
Purpose of review Xenotransplantation offers the opportunity to alleviate the imbalance between the demand of patients with end stage organ failure and the supply of organs available for transplantation but remains aspirational. This review highlight
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318e3001bf61cd453ac997bf09ccb55f
https://pubmed.ncbi.nlm.nih.gov/31385887
https://pubmed.ncbi.nlm.nih.gov/31385887
Autor:
Dan M. Roden, Chee Chew Lim, Sneha Chatterjee, Calum A. MacRae, Jeffrey S. Bennett, Lin Zhong, Amy E. Kelly, Tamara Y. Robinson, Shannon Coy, Jason R Becker, Jordan T. Shin, Cristi L. Galindo, Daniela Panáková
Publikováno v:
Development. 141:335-345
Organ development is a highly regulated process involving the coordinated proliferation and differentiation of diverse cellular populations. The pathways regulating cell proliferation and their effects on organ growth are complex and for many organs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beaad45700b3fee7a03034eae2b641a9
https://doi.org/10.1242/dev.100370
https://doi.org/10.1242/dev.100370
Autor:
Hannah L. Semigran, Matthew Dai, Marc J. Semigran, Patricia A. Collins, Jennifer E. Ward, David C. Seldin, Jordan T. Shin
Publikováno v:
Amyloid. 19:191-196
AL cardiomyopathy leading to heart failure (HF) represents a significant cause of morbidity and mortality in systemic amyloidosis. However, the paucity of robust in vivo models of AL-induced cardiac dysfunction has limited our ability to probe the me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46716917c7babe484a44487fff47bb8d
https://doi.org/10.3109/13506129.2012.733741
https://doi.org/10.3109/13506129.2012.733741
Publikováno v:
Physiological Genomics. 42:300-309
Phenotype-driven screens in larval zebrafish have transformed our understanding of the molecular basis of cardiovascular development. Screens to define the genetic determinants of physiological phenotypes have been slow to materialize as a result of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f6d79e73e45045d8f0a679794ef6150
https://doi.org/10.1152/physiolgenomics.00206.2009
https://doi.org/10.1152/physiolgenomics.00206.2009
Autor:
William F. Sewell, Libin Wang, Calum A. MacRae, Jordan T. Shin, Sang D. Kim, Christine E. Seidman, Leonard I. Zon, Jonathan G. Seidman
Publikováno v:
Development. 135:3425-3434
To investigate the mechanisms by which mutations in the human transcriptional co-activator EYA4 gene cause sensorineural hearing loss that can occur in association with dilated cardiomyopathy, we studied eya4 expression during zebrafish development a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::074e0579824e0fd21928a51725c701d5
https://doi.org/10.1242/dev.012237
https://doi.org/10.1242/dev.012237
Autor:
Jing-Ruey Yeh, Haley R. Noonan, Anne E. Carpenter, Rania Baker, Ana M. Metelo, Randall T. Peterson, Othon Iliopoulos, Yiyun Zhang, Lee Kamentsky, Jordan T. Shin, Ellen van Rooijen, Xiang Li, Youngnam N. Jin
Publikováno v:
The Journal of clinical investigation. 125(5)
Patients with a germline mutation in von Hippel-Lindau (VHL) develop renal cell cancers and hypervascular tumors of the brain, adrenal glands, and pancreas as well as erythrocytosis. These phenotypes are driven by aberrant expression of HIF2α, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::265f4ebba04357156a7495cf546c84e3
https://pubmed.ncbi.nlm.nih.gov/25866969
https://pubmed.ncbi.nlm.nih.gov/25866969
Autor:
Craig T. Basson, Patrick T. Ellinor, Jordan T. Shin, Eva Plovie, Sabine Sasse-Klaassen, Brenda Gerull, Calum A. MacRae, Arnd Heuser, Thomas Wichter, Ludwig Thierfelder, Bruce B. Lerman, Katja S. Grossmann
Publikováno v:
The American Journal of Human Genetics. 79(6):1081-1088
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a genetically heterogeneous heart-muscle disorder characterized by progressive fibrofatty replacement of right ventricular myocardium and an increased risk of sudden cardiac death. Mutations i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e4aeaca438d5dc0cfd12ff9abd4129e
Autor:
Rachel Moore, Ivan Ovcharenko, Amy Ronco, Jordan T. Shin, Calum A. MacRae, C. Geoffrey Burns, James R. Priest
Publikováno v:
Nucleic Acids Research
Whole genome comparisons of distantly related species effectively predict biologically important sequences--core genes and cis-acting regulatory elements (REs)--but require experimentation to verify biological activity. To examine the efficacy of com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a17f66e233d638bc44079548599fbb4e
http://europepmc.org/articles/PMC1236720
http://europepmc.org/articles/PMC1236720
Publikováno v:
Circulation. 107:2880-2883
Background— Atrial fibrillation (AF), the most common clinical arrhythmia, is a major cause of morbidity and mortality. Although AF is often associated with other cardiovascular conditions, many patients present without an obvious etiology. Inherit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ced3f043c10caab86d99ab141281435
https://doi.org/10.1161/01.cir.0000077910.80718.49
https://doi.org/10.1161/01.cir.0000077910.80718.49