Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jordan Sprenz"'
Autor:
Megan Kopp, S. Munir Alam, Sophie M. C. Gobeil, R Parks, Priyamvada Acharya, Zekun Mu, Rory Henderson, Gregory D. Sempowski, Robert J. Edwards, Kartik Manne, Dapeng Li, Kevin O. Saunders, Jordan Sprenz, Katarzyna Janowska, Wilton B. Williams, Margaret Deyton, Xiaozhi Lu, Brian E. Watts, Barton F. Haynes, Thomas H. Oguin, Victoria Stalls, Katayoun Mansouri, David C. Montefiori
Publikováno v:
bioRxiv
Nature structural & molecular biology
Nature Structural & Molecular Biology
Nature structural & molecular biology
Nature Structural & Molecular Biology
The impact of COVID-19 and the urgency to develop a vaccine against the SARS-CoV-2 virus cannot be overstated. The viral fusion spike (S) protein ectodomain is the primary target for vaccine development. Here we report an unexpected cold sensitivity
Autor:
Victoria Stalls, Gregory D. Sempowski, Katarzyna Janowska, Robert Parks, Rory Henderson, Margaret Deyton, Thomas H. Oguin, R. Ryan Meyerhoff, Wilton B. Williams, Katayoun Mansouri, Kartik Manne, Jordan Sprenz, Robert J. Edwards, Megan Kopp, Kevin O. Saunders, Priyamvada Acharya, Barton F. Haynes
Publikováno v:
bioRxiv
SummaryThe COVID-19 pandemic caused by SARS-CoV-2 has escalated into a global crisis. The spike (S) protein that mediates cell entry and membrane fusion is the current focus of vaccine and therapeutic antibody development efforts. The S protein, like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d19f640dfed198231724eb1e9dfe17d2
https://europepmc.org/articles/PMC7337383/
https://europepmc.org/articles/PMC7337383/
Autor:
Katarzyna Janowska, Guillaume Stewart-Jones, Ye Zhou, Bhavna Hora, Naomi Bronkema, Tyler Evangelous, Alberto Bartesaghi, John R. Perfect, Hui Li, Robert A. Seder, Michael S. Seaman, Celia C. LaBranche, A. Yousef Abuahmad, Jordan Sprenz, Joseph R. Francica, M. Anthony Moody, Baptiste Aussedat, S. Munir Alam, Garnett Kelsoe, Sampa Santra, Barton F. Haynes, Richard Laga, Priyamvada Acharya, Katayoun Mansouri, Daniela Fera, Victoria Stalls, Nathan I. Nicely, Margaret Deyton, Allen L. Hsu, Madison Berry, George M. Shaw, Megan Kopp, William E. Walkowicz, David C. Montefiori, Gregory D. Sempowski, Matthew S. Lee, Sophie M. C. Gobeil, Mario J. Borgnia, Todd Bradley, Thomas H. Oguin, R. Ryan Meyerhoff, Robert Parks, Kevin Wiehe, Mattia Bonsignori, Peter D. Kwong, Kartik Manne, Geoffrey M. Lynn, Rory Henderson, Robert J. Edwards, Wilton B. Williams, Andrew Foulger, Kevin O. Saunders
Publikováno v:
Cell
Natural antibodies (Abs) can target host glycans on the surface of pathogens. We studied the evolution of glycan-reactive B cells of rhesus macaques and humans using glycosylated HIV-1 envelope (Env) as a model antigen. 2G12 is a broadly neutralizing