Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jordan Showell"'
Autor:
Man Chun John Ma, Saber Tadros, Alyssa Bouska, Tayla Heavican, Haopeng Yang, Qing Deng, Dalia Moore, Ariz Akhter, Keenan Hartert, Neeraj Jain, Jordan Showell, Sreejoyee Ghosh, Lesley Street, Marta Davidson, Christopher Carey, Joshua Tobin, Deepak Perumal, Julie M. Vose, Matthew A. Lunning, Aliyah R. Sohani, Benjamin J. Chen, Shannon Buckley, Loretta J. Nastoupil, R. Eric Davis, Jason R. Westin, Nathan H. Fowler, Samir Parekh, Maher Gandhi, Sattva Neelapu, Douglas Stewart, Kapil Bhalla, Javeed Iqbal, Timothy Greiner, Scott J. Rodig, Adnan Mansoor, Michael R. Green
Publikováno v:
Haematologica, Vol 107, Iss 3 (2021)
B-cell non-Hodgkin lymphoma (B-NHL) encompasses multiple clinically and phenotypically distinct subtypes of malignancy with unique molecular etiologies. Common subtypes of B-NHL, such as diffuse large B-cell lymphoma, have been comprehensively interr
Externí odkaz:
https://doaj.org/article/fc029b784cbf42fa99be555459101032
Autor:
Ann P. Quick, BA, Andrew P. Landstrom, MD, PhD, Qiongling Wang, PhD, David L. Beavers, MD, PhD, Julia O. Reynolds, BS, Giselle Barreto-Torres, PhD, Viet Tran, MD, Jordan Showell, BS, Leonne E. Philippen, MSc, Shaine A. Morris MD, MPH, Darlene Skapura, BS, J. Martijn Bos, MD, Steen E. Pedersen, PhD, Robia G. Pautler, PhD, Michael J. Ackerman, MD, PhD, Xander H.T. Wehrens, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 2, Iss 1, Pp 56-67 (2017)
Summary: Junctophilin-2 (JPH2) is a structural calcium (Ca2+) handling protein, which approximates the cardiomyocyte transverse tubules (TTs) to the sarcoplasmic reticulum. This facilitates communication of the voltage-gated Ca2+ channel and the ryan
Externí odkaz:
https://doaj.org/article/d086c9c35bcd4a099db4e3951cde466e
Autor:
Atish Kizhakeyil, Sreejoyee Ghosh, Estela Rojas-Neira, Qing Deng, Jared Henderson, Jordan Showell, Ari Melnick, Wendy Beguelin, Francisco Vega, Loretta J. Nastoupil, Michael R Green
Publikováno v:
Blood. 140:1700-1701
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b602bd5737c4e78b47d17e5ada88e425
https://doi.org/10.1182/blood-2022-167086
https://doi.org/10.1182/blood-2022-167086
Autor:
Nathan Fowler, Yuanxin Wang, Sattva S. Neelapu, Ruiping Wang, Sreejoyee Ghosh, Linghua Wang, Hans C. Lee, Jason R. Westin, Felipe Samaniego, Shaojun Zhang, Enyu Dai, Haopeng Yang, R. Eric Davis, Sridevi Patchva, Paolo Strati, Ryan Sun, Guangchun Han, Minghao Dang, Luis Fayad, Man Chun John Ma, Qi Zhang, Nahum Puebla-Osorio, Qing Deng, Runzhe Chen, Loretta J. Nastoupil, Jordan Showell, Beth Chasen, Neeraj Jain, Frederick B. Hagemeister, Michael R. Green
Publikováno v:
Nat Med
Autologous chimeric antigen receptor (CAR) T cell therapies targeting CD19 have high efficacy in large B cell lymphomas (LBCLs), but long-term remissions are observed in less than half of patients, and treatment-associated adverse events, such as imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::542333622fe458434f84bc54e193b7e5
https://doi.org/10.1038/s41591-020-1061-7
https://doi.org/10.1038/s41591-020-1061-7
Autor:
Qiongling Wang, Giselle Barreto-Torres, Viet Tran, Leonne E Philippen, Jordan Showell, Robia G. Pautler, Shaine A. Morris, Julia O. Reynolds, Ann P. Quick, Michael J. Ackerman, J. Martijn Bos, Andrew P. Landstrom, David L. Beavers, Darlene G. Skapura, Xander H.T. Wehrens, Steen E. Pedersen
Publikováno v:
JACC: Basic to Translational Science, Vol 2, Iss 1, Pp 56-67 (2017)
Summary: Junctophilin-2 (JPH2) is a structural calcium (Ca2+) handling protein, which approximates the cardiomyocyte transverse tubules (TTs) to the sarcoplasmic reticulum. This facilitates communication of the voltage-gated Ca2+ channel and the ryan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38e2e6c6c7911e4790d622a7b3833ddb
Autor:
Ann P. Quick, Xander H.T. Wehrens, David Y. Chiang, Maha Khalid, Leonne E Philippen, David L. Beavers, Qiongling Wang, Giselle Barreto-Torres, Jordan Showell, Mark McCauley, Hannah M. Campbell, Julia O. Reynolds, Guoliang Wang, Arjen Scholten
Publikováno v:
Circulation Research. 120:110-119
Rationale: Junctional membrane complexes (JMCs) in myocytes are critical microdomains, in which excitation–contraction coupling occurs. Structural and functional disruption of JMCs underlies contractile dysfunction in failing hearts. However, the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78e0cb5bf4914d7326ea947877b1ebcc
https://doi.org/10.1161/circresaha.116.309977
https://doi.org/10.1161/circresaha.116.309977
Autor:
David L. Beavers, Ann P. Quick, Giselle Barreto-Torres, Qiongling Wang, Xander H.T. Wehrens, Christopher C. Glembotski, Jordan Showell, Leonne E Philippen, Shirin Doroudgar, Donna J. Thuerauf, Julia O. Reynolds
Publikováno v:
International Journal of Cardiology. 225:371-380
Background Junctophilin-2 (JPH2) is the primary structural protein for the coupling of transverse (T)-tubule associated cardiac L-type Ca channels and type-2 ryanodine receptors on the sarcoplasmic reticulum within junctional membrane complexes (JMCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad64a8f8ff27b4221d601a56b1208f06
https://doi.org/10.1016/j.ijcard.2016.10.021
https://doi.org/10.1016/j.ijcard.2016.10.021
Autor:
Sattva S. Neelapu, Benjamin J. Chen, Aliyah R. Sohani, Marta Davidson, Dalia Moore, Keenan Hartert, Joshua W.D. Tobin, Douglas A. Stewart, Saber Tadros, Sreejoyee Ghosh, Alyssa Bouska, Matthew A. Lunning, Shannon M. Buckley, Deepak Perumal, Tayla Heavican, Christopher D. Carey, Julie M. Vose, Kapil Bhalla, Loretta J. Nastoupil, Man Chun John Ma, Ariz Akhter, Javeed Iqbal, Samir Parekh, Michael R. Green, Jordan Showell, Maher K. Gandhi, Neeraj Jain, Scott J. Rodig, Haopeng Yang, Lesley Street, Qing Deng, R. Eric Davis, Adnan Mansoor, Timothy Greiner, Nathan Fowler, Jason R. Westin
B-cell non-Hodgkin’s lymphoma (B-NHL) encompasses multiple clinically and phenotypically distinct subtypes of malignancy with unique molecular etiologies. Common subtypes of B-NHL such as diffuse large B-cell lymphoma (DLBCL) have been comprehensiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5246f6ff655c2b3f0fa07552f81ec77d
https://doi.org/10.1101/674259
https://doi.org/10.1101/674259
Autor:
Julia O, Reynolds, Ann P, Quick, Qiongling, Wang, David L, Beavers, Leonne E, Philippen, Jordan, Showell, Giselle, Barreto-Torres, Donna J, Thuerauf, Shirin, Doroudgar, Christopher C, Glembotski, Xander H T, Wehrens
Publikováno v:
International journal of cardiology. 225
Junctophilin-2 (JPH2) is the primary structural protein for the coupling of transverse (T)-tubule associated cardiac L-type Ca channels and type-2 ryanodine receptors on the sarcoplasmic reticulum within junctional membrane complexes (JMCs) in cardio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7b18e7b007f1703c98ed72cc44784311
https://pubmed.ncbi.nlm.nih.gov/27760414
https://pubmed.ncbi.nlm.nih.gov/27760414
Autor:
Robia G. Pautler, Andrew P. Landstrom, Leonne E Philippen, David L. Beavers, Jordan Showell, Ann P. Quick, Xander H.T. Wehrens, Shaine A. Morris
Publikováno v:
Circulation Research. 117
Background: Dysfunctional intracellular Ca2+ handling has been implicated in adverse cardiac remodeling leading to hypertrophy and failure. Recent evidence has linked mutations in the Ca2+ handling protein Junctophilin-2 (JPH2) with the development o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9a0ff949df6331740bdc8b386acb56d
https://doi.org/10.1161/res.117.suppl_1.35
https://doi.org/10.1161/res.117.suppl_1.35