Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jordan S. Brown"'
Autor:
Zhenzhen Du, Kun Shi, Jordan S. Brown, Tao He, Wei-Sheng Wu, Ying Zhang, Heng-Chi Lee, Donglei Zhang
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112859- (2023)
Summary: Biomolecular condensates have been shown to interact in vivo, yet it is unclear whether these interactions are functionally meaningful. Here, we demonstrate that cooperativity between two distinct condensates—germ granules and P bodies—i
Externí odkaz:
https://doaj.org/article/d3cc839beb6142109c3a112ce23da2db
Autor:
Wenjun Chen, Jordan S. Brown, Tao He, Wei-Sheng Wu, Shikui Tu, Zhiping Weng, Donglei Zhang, Heng-Chi Lee
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Phase separated, membrane-less germ granules preserve fertility and cellular function in animal germ cells. Here the authors show that loss of germ granules impacts piRNA pathway fidelity in the recognition of self and non-self nucleic acids.
Externí odkaz:
https://doaj.org/article/d8b863c6d92b413c8d5717dec515c6bb
Publikováno v:
Non-Coding RNA, Vol 8, Iss 1, p 6 (2022)
Non-coding RNAs, such as miRNAs and piRNAs, play critical roles in gene regulation through base-pairing interactions with their target molecules. The recent development of the crosslinking, ligation, and sequencing of hybrids (CLASH) method has allow
Externí odkaz:
https://doaj.org/article/442bbd8204404d80952fef51574c5df1
Autor:
Zhenzhen Du, Kun Shi, Jordan S. Brown, Tao He, Wei-Sheng Wu, Ying Zhang, Heng-Chi Lee, Donglei Zhang
The formation of biomolecular condensates has emerged as a critical mechanism for compartmentation in living cells. Despite interactions between distinct condensates having been reported, the biological relevance of these interactions remains elusive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf42c771f8646d51b267db9c2adaedce
https://doi.org/10.1101/2022.11.01.514641
https://doi.org/10.1101/2022.11.01.514641
BackgroundPIWI-interacting RNAs (piRNAs) protect genome integrity by silencing transposon mRNAs and some endogenous mRNAs in various animals. However, C. elegans piRNAs fail to trigger gene silencing at many sequence-based predicted targeting sites.R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a4e5989f2853cc45f9280600cdfb31f
https://doi.org/10.1101/2022.06.08.495319
https://doi.org/10.1101/2022.06.08.495319
Autor:
Wenjun Chen, Xiaoyan Song, Yabing Hu, Ying Zhang, Donglei Zhang, Karen Bennett, Sierra Schwabach, Jordan S. Brown, Heng-Chi Lee, Charles F. Lang, Edwin Munro
Publikováno v:
Genetics. 215:421-434
Germ granules, also known as P granules in Caenorhabditis elegans, are phase-separated cellular bodies that are frequently found at the perinuclear region of germ cell nuclei in various animals. However... P granules are phase-separated liquid drople
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe471353bfbaaa2718a9055d0c9338d9
https://doi.org/10.1534/genetics.120.303052
https://doi.org/10.1534/genetics.120.303052
Autor:
Wenjun, Chen, Yabing, Hu, Charles F, Lang, Jordan S, Brown, Sierra, Schwabach, Xiaoyan, Song, Ying, Zhang, Edwin, Munro, Karen, Bennett, Donglei, Zhang, Heng-Chi, Lee
Publikováno v:
Genetics
P granules are phase-separated liquid droplets that play important roles in the maintenance of germ cell fate in Caenorhabditis elegans. Both the localization and formation of P granules are highly dynamic, but mechanisms that regulate such processes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d81cf78a5bb229140da04759967afcf4
https://pubmed.ncbi.nlm.nih.gov/32245789
https://pubmed.ncbi.nlm.nih.gov/32245789
Autor:
Yabing Hu, Charles F. Lang, Wenjun Chen, Ed Munro, Jordan S. Brown, Xiaoyan Song, Heng-Chi Lee, Karen Bennett, Donglei Zhang
P granules are phase-separated liquid droplets that play important roles in the maintenance of the germ cell fate in C. elegans. The localization and formation of P granules are highly dynamic, but mechanisms that regulate such processes remain poorl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11c7e3c465b1ba3fe1e01b581ce573fa
https://doi.org/10.1101/760256
https://doi.org/10.1101/760256
pirScan: a webserver to predict piRNA targeting sites and to avoid transgene silencing in C. elegans
Autor:
Wei Che Huang, Wei Sheng Wu, Xiaoyan Song, Shikui Tu, Zhiping Weng, Donglei Zhang, Jordan S. Brown, Heng-Chi Lee, Hao Chen
Publikováno v:
Nucleic Acids Research
pirScan is a web-based tool for identifying C. elegans piRNA-targeting sites within a given mRNA or spliced DNA sequence. The purpose of our tool is to allow C. elegans researchers to predict piRNA targeting sites and to avoid the persistent germline
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::759acdfc00c40ee60a316690f925c7e2
https://pubmed.ncbi.nlm.nih.gov/29897582
https://pubmed.ncbi.nlm.nih.gov/29897582
Autor:
Jordan S. Brown, Gordon G. McNickle
Publikováno v:
Journal of Ecology. 102:963-971
Summary Below-ground competition is intense and may dramatically reduce plant performance. However, there is still no consensus on the best strategies plants should use to maximize competitive ability in soil. Some suggest plants should grow roots ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45fa158570f2499e21770c7dfb7658f3
https://doi.org/10.1111/1365-2745.12259
https://doi.org/10.1111/1365-2745.12259