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A cell-based screen reveals that the albendazole metabolite, albendazole sulfone, targets Wolbachia.
Autor:
Laura R Serbus, Frederic Landmann, Walter M Bray, Pamela M White, Jordan Ruybal, R Scott Lokey, Alain Debec, William Sullivan
Publikováno v:
PLoS Pathogens, Vol 8, Iss 9, p e1002922 (2012)
Wolbachia endosymbionts carried by filarial nematodes give rise to the neglected diseases African river blindness and lymphatic filariasis afflicting millions worldwide. Here we identify new Wolbachia-disrupting compounds by conducting high-throughpu
Externí odkaz:
https://doaj.org/article/462c1353791e401ebbfccec1727587c5