Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Jordan R, Yaron"'
Publikováno v:
Bioengineering & Translational Medicine, Vol 9, Iss 3, Pp n/a-n/a (2024)
Abstract Dermal wounds are a major global health burden made worse by common comorbidities such as diabetes and infection. Appropriate wound closure relies on a highly coordinated series of cellular events, ultimately bridging tissue gaps and regener
Externí odkaz:
https://doaj.org/article/a3a10bdc6e604c0aac06e7ccf0fe71a0
Autor:
Sahil Inamdar, Abhirami P. Suresh, Joslyn L. Mangal, Nathan D. Ng, Alison Sundem, Christopher Wu, Kelly Lintecum, Abhirami Thumsi, Taravat Khodaei, Michelle Halim, Nicole Appel, Madhan Mohan Chandra Sekhar Jaggarapu, Arezoo Esrafili, Jordan R. Yaron, Marion Curtis, Abhinav P. Acharya
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Inhibition of glycolysis in immune cells and cancer cells diminishes their activity, and thus combining immunotherapies with glycolytic inhibitors is challenging. Herein, a strategy is presented where glycolysis is inhibited in cancer cells
Externí odkaz:
https://doaj.org/article/1b742fa55db040f2888e0d48066e3a19
Autor:
Jordan R. Yaron, Selin Bakkaloglu, Nicole A. Grigaitis, Farhan H. Babur, Sophia Macko, Samantha Rhodes, Solenne Norvor-Davis, Kaushal Rege
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The inflammasome is a multiprotein complex critical for the innate immune response to injury. Inflammasome activation initiates healthy wound healing, but comorbidities with poor healing, including diabetes, exhibit pathologic, sustained activation w
Externí odkaz:
https://doaj.org/article/ac0d12731c1b4a4a9ad2121421af421f
Autor:
Deepanjan Ghosh, Christopher M. Salinas, Shubham Pallod, Jordan Roberts, Inder Raj S. Makin, Jordan R. Yaron, Russell S. Witte, Kaushal Rege
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 2, Pp n/a-n/a (2023)
Abstract Injuries caused by surgical incisions or traumatic lacerations compromise the structural and functional integrity of skin. Immediate approximation and robust repair of skin are critical to minimize occurrences of dehiscence and infection tha
Externí odkaz:
https://doaj.org/article/25600f4ef07a406c9adda1bbd4e5f699
RNA Virus Gene Signatures Detected in Patients With Cardiomyopathy After Chemotherapy; A Pilot Study
Autor:
Kyle Varkoly, Shaoyuan Tan, Roxana Beladi, David Fonseca, Isabela Rivabem Zanetti, Simona Kraberger, Chintan Shah, Jordan R. Yaron, Liqiang Zhang, Michael Juby, Ayman Fath, Sriram Ambadapadi, Melanie House, Paul Maranian, Carl J. Pepine, Arvind Varsani, Jan Moreb, Stacey Schultz-Cherry, Alexandra R. Lucas
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundViral infections are pervasive and leading causes of myocarditis. Immune-suppression after chemotherapy increases opportunistic infections, but the incidence of virus-induced myocarditis is unknown.ObjectiveAn unbiased, blinded screening fo
Externí odkaz:
https://doaj.org/article/286ff97e896540d9825a6b8182791a9a
Autor:
Sahil Inamdar, Abhirami P. Suresh, Joslyn L. Mangal, Nathan D. Ng, Alison Sundem, Hoda Shokrollahzadeh Behbahani, Thomas E. Rubino, Xiaojian Shi, Sharon T. Loa, Jordan R. Yaron, Taro Hitosugi, Matthew Green, Haiwei Gu, Marion Curtis, Abhinav P. Acharya
Publikováno v:
Journal of Controlled Release. 358:541-554
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a175ff4d062296932a3010ad87cf9024
https://doi.org/10.1016/j.jconrel.2023.05.014
https://doi.org/10.1016/j.jconrel.2023.05.014
Autor:
Brent Ju, Owen Guo, Dathe Z. Benissan-Messan, McKinley H. Shawver, Peng Chen, Bingchuan Geng, Siqi Wei, Jordan R. Yaron, Alexandra R. Lucas, Hua Zhu
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Purpose: Chemical corneal injuries carry a high morbidity and commonly lead to visual impairment. Here, we investigate the role of Serp-1, a serine protease inhibitor, in corneal wound healing.Methods: An alkaline-induced corneal injury was induced i
Externí odkaz:
https://doaj.org/article/2a4c4e5e6d3341e9a7991eb8786abc95
Autor:
Jordan R. Yaron, Hao Chen, Sriram Ambadapadi, Liqiang Zhang, Amanda M. Tafoya, Barbara H. Munk, Dara N. Wakefield, Jorge Fuentes, Bruno J. Marques, Krishna Harripersaud, Mee Yong Bartee, Jennifer A. Davids, Donghang Zheng, Kenneth Rand, Lisa Dixon, Richard W. Moyer, William L. Clapp, Alexandra R. Lucas
Publikováno v:
Journal of Inflammation, Vol 16, Iss 1, Pp 1-9 (2019)
Abstract Background Ischemia-reperfusion injury (IRI) is an antigen-independent, innate immune response to arterial occlusion and ischemia with subsequent paradoxical exacerbation after reperfusion. IRI remains a critical problem after vessel occlusi
Externí odkaz:
https://doaj.org/article/2a583ac6ff0c40f1beb5e17e5a621f77
Autor:
Jacek M. Kwiecien, Wojciech Dabrowski, Barbara Marzec-Kotarska, Christian J. Kwiecien-Delaney, Jordan R. Yaron, Liqiang Zhang, Lauren Schutz, Alexandra R. Lucas
Publikováno v:
Folia Neuropathologica, Vol 57, Iss 1, Pp 41-50 (2019)
Spinal cord injury (SCI)-initiated inflammation was treated with anti-inflammatory reagents. We compared local spinal cord or intraperitoneal infusion of two Myxoma virus derived immune modulating proteins, Serp-1 and M-T7, with dexamethasone (DEX).
Externí odkaz:
https://doaj.org/article/d3fc00cdebe54fd1a23693816153ca8a
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
The making and breaking of clots orchestrated by the thrombotic and thrombolytic serine protease cascades are critical determinants of morbidity and mortality during infection and with vascular or tissue injury. Both the clot forming (thrombotic) and
Externí odkaz:
https://doaj.org/article/ceea2b51061f4bdfbeb5d3078b36bcca