Výsledky vyhledávání - "Jordan Poles"

Akademický článek

Coinfections and antimicrobial use in patients hospitalized with coronavirus disease 2019 (COVID-19) across a single healthcare system in New York City: A retrospective cohort study

Autor: Prithiv J. Prasad, Jordan Poles, Ioannis M. Zacharioudakis, Yanina Dubrovskaya, Dinuli Delpachitra, Eduardo Iturrate, Sigridh Muñoz-Gómez

Publikováno v: Antimicrobial Stewardship & Healthcare Epidemiology, Vol 2 (2022)

Abstract Background and objective: With the coronavirus disease 2019 (COVID-19) pandemic, rates of in-hospital antimicrobial use increased due to perceived bacterial and fungal coinfections along with COVID-19. We describe the incidence of these coi

Externí odkaz: https://doaj.org/article/e4c956a7bfdb494298c428e6683e9b70

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The helminth glycoprotein omega-1 improves metabolic homeostasis in obese mice through type 2 immunity-independent inhibition of food intake

Publikováno v: FASEB Journal, 35(2). WILEY
FASEB Journal, 35(2)
The FASEB Journal
FASEB Journal 35 (2021) 2

Type 2 immunity plays an essential role in the maintenance of metabolic homeostasis and its disruption during obesity promotes meta-inflammation and insulin resistance. Infection with the helminth parasite Schistosoma mansoni and treatment with its s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a388d693e109e6d697c66e14ae98fd6e
http://hdl.handle.net/1887/3214670

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Quickstart for SIRD Modeling of the COVID-19 Outbreak

Autor: Jordan Poles

Publikováno v: Outbreak.

Overview: There are a number of different methodologies that one can employ in order to model the outbreak of an infectious disease, in this case the novel 2019 coronavirus (COVID-19). Some, like generalized logistic models or Richards models rely on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::34186f11c257eca17d78541a0ef94201
https://doi.org/10.34235/8205b620-fe85-43b2-bf14-a593b766cf07-2

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Single-cell analysis of fate-mapped macrophages reveals heterogeneity, including stem-like properties, during atherosclerosis progression and regression

Autor: Jordan Poles, Hitoo Nishi, Caroline S McCauley, Stephen A. Ramsey, Stephen T. Yeung, Ada Weinstock, Karishma Rahman, P'ng Loke, Xiang Niu, Edward A. Fisher, Jian-Da Lin, Emily J. Brown, Nikollaq Vozhilla

Publikováno v: JCI insight. 4(4)

Atherosclerosis is a leading cause of death worldwide in industrialized countries. Disease progression and regression are associated with different activation states of macrophages derived from inflammatory monocytes entering the plaques. The feature

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59669afb3205d265f152c3262e1b8659
https://pubmed.ncbi.nlm.nih.gov/30830865

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Inferred metagenomic comparison of mucosal and fecal microbiota from individuals undergoing routine screening colonoscopy reveals similar differences observed during active inflammation

Autor: Yvonne Al Lim, Jordan Poles, Soo Ching Lee, P'ng Loke, Martin J. Wolff, Mei San Tang, Kek Heng Chua, Michael Davenport, Jacqueline M. Leung, Ilseung Cho

Publikováno v: Gut Microbes. 6:48-56

The mucosal microbiota lives in close proximity with the intestinal epithelium and may interact more directly with the host immune system than the luminal/fecal bacteria. The availability of nutrients in the mucus layer of the epithelium is also very

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e18debada28287616189d843c965ccc4
https://doi.org/10.1080/19490976.2014.1000080

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Vitamin A mediates conversion of monocyte-derived macrophages into tissue-resident macrophages during alternative activation

Autor: Jian-Da Lin, Edward A. Fisher, Jordan Poles, Uma Mahesh Gundra, Natasha M. Girgis, Nikollaq Vozhilla, Hendrik J. P. van der Zande, P'ng Loke, Mireille Ouimet, Michael A. Gonzalez, Kathryn J. Moore, Mei San Tang, Lily J Ma

Publikováno v: Nature immunology

It remains unclear whether activated inflammatory macrophages can adopt features of tissue-resident macrophages, or what mechanisms might mediate such a phenotypic conversion. Here we show that vitamin A is required for the phenotypic conversion of i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cba9ac9d19cb4be0728112310fa38a07
https://pubmed.ncbi.nlm.nih.gov/28690329

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Lung dendritic cells induce migration of protective T cells to the gastrointestinal tract

Autor: Jordan Poles, Darren Ruane, Daniel Mucida, Ed C. Lavelle, Hongfa Zhu, Cheolho Cheong, Yoonkyung Do, Klara Velinzon, Jae-Hoon Choi, Bernardo S. Reis, Saurabh Mehandru, Lloyd Mayer, Ralph M. Steinman, Lucas Brane, Natalie Studt

Publikováno v: The Journal of Experimental Medicine
Gastroenterology

Lung DCs induce the expression of gut-homing molecules on T cells, resulting in their migration to the GI tract and protection against Salmonella infection after immunization
Developing efficacious vaccines against enteric diseases is a global c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26004e7b778dc834b98e15e4fe1da873
http://europepmc.org/articles/PMC3754860

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