Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jordan Pinder"'
Autor:
Charles Vadnais, Riyan Chen, Jennifer Fraszczak, Zhenbao Yu, Jonathan Boulais, Jordan Pinder, Daria Frank, Cyrus Khandanpour, Josée Hébert, Graham Dellaire, Jean-François Côté, Stéphane Richard, Alexandre Orthwein, Elliot Drobetsky, Tarik Möröy
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
The transcription factor GFI1 mediates the DNA damage response (DDR) of T cells through a yet unknown mechanism. Here the authors show that GFI1 can adopt non-transcriptional roles during DDR, enabling PRMT1 to bind and methylate the DNA repair prote
Externí odkaz:
https://doaj.org/article/84219a0ff4704d3586e8769eac7e762a
Publikováno v:
Haematologica, Vol 105, Iss 10 (2019)
GFI1B-related thrombocytopenia (GFI1B-RT) is a rare bleeding disorder mainly caused by the presence of truncated GFI1B proteins with dominant-negative properties. The disease is characterized by low platelet counts, the presence of abnormal platelets
Externí odkaz:
https://doaj.org/article/2d9af480dbf7402cbeeeb9d468fdbe65
Autor:
Alkmini Kalousi, Anne-Sophie Hoffbeck, Platonas N. Selemenakis, Jordan Pinder, Kienan I. Savage, Kum Kum Khanna, Laurent Brino, Graham Dellaire, Vassilis G. Gorgoulis, Evi Soutoglou
Publikováno v:
Cell Reports, Vol 11, Iss 1, Pp 149-163 (2015)
Cells experience damage from exogenous and endogenous sources that endanger genome stability. Several cellular pathways have evolved to detect DNA damage and mediate its repair. Although many proteins have been implicated in these processes, only rec
Externí odkaz:
https://doaj.org/article/cc2a41e5007e4ca08930877ab8c04887
Autor:
David M. Langenau, Graham Dellaire, Raul Mostoslavsky, Richard A. Young, A. Thomas Look, Wilhelm Haas, Marjorie A. Oettinger, John M. Asara, Ruslan I. Sadreyev, Lewis B. Silverman, Kimberly Stegmaier, Alejandro Gutierrez, Khalid Shah, Deepak Bhere, Mattia Lion, Myriam Boukhali, Esha Jain, Manon de Waard, Debra Toiber, Gabriela Alexe, Aleksey Molodtsov, Nouran S. Abdelfattah, Marc Mansour, Yuka Namiki, Brian J. Abraham, Jessica S. Blackburn, Marina Theodorou, Barbara Martinez-Pastor, Jordan Pinder, Riadh Lobbardi
Table S4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0913dae3a8e3abe12dc8fd9f92609b39
https://doi.org/10.1158/2159-8290.22532222.v1
https://doi.org/10.1158/2159-8290.22532222.v1
Autor:
David M. Langenau, Graham Dellaire, Raul Mostoslavsky, Richard A. Young, A. Thomas Look, Wilhelm Haas, Marjorie A. Oettinger, John M. Asara, Ruslan I. Sadreyev, Lewis B. Silverman, Kimberly Stegmaier, Alejandro Gutierrez, Khalid Shah, Deepak Bhere, Mattia Lion, Myriam Boukhali, Esha Jain, Manon de Waard, Debra Toiber, Gabriela Alexe, Aleksey Molodtsov, Nouran S. Abdelfattah, Marc Mansour, Yuka Namiki, Brian J. Abraham, Jessica S. Blackburn, Marina Theodorou, Barbara Martinez-Pastor, Jordan Pinder, Riadh Lobbardi
Supplementary Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d38cf5f62436e4a13b0c92f5230c769
https://doi.org/10.1158/2159-8290.22532234.v1
https://doi.org/10.1158/2159-8290.22532234.v1
Publikováno v:
Haematologica
GFI1B-related thrombocytopenia (GFI1B-RT) is a rare bleeding disorder mainly caused by the presence of truncated GFI1B proteins with dominant-negative properties. The disease is characterized by low platelet counts, the presence of abnormal platelets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91052ed0ed130ff93182f59c7c9c1d48
https://doi.org/10.3324/haematol.2019.222596
https://doi.org/10.3324/haematol.2019.222596
Autor:
Brian J. Abraham, Manon De Waard, Marjorie A. Oettinger, Marc R. Mansour, Debra Toiber, Wilhelm Haas, Mattia Lion, Myriam Boukhali, A. Thomas Look, Graham Dellaire, Alejandro Gutierrez, Nouran S. Abdelfattah, Marina C. Theodorou, Deepak Bhere, Esha Jain, Jessica S. Blackburn, Lewis B. Silverman, Khalid Shah, Ruslan I. Sadreyev, Kimberly Stegmaier, Riadh Lobbardi, Barbara Martinez-Pastor, Yuka Namiki, Richard A. Young, Raul Mostoslavsky, Jordan Pinder, David M. Langenau, Gabriela Alexe, John M. Asara, Aleksey Molodtsov
Publikováno v:
Cancer Discovery. 7:1336-1353
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive malignancy of thymocytes. Using a transgenic screen in zebrafish, thymocyte selection–associated high mobility group box protein (TOX) was uncovered as a collaborating oncogenic driver th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59368cefd123b3c2db047f4aff5baab8
https://doi.org/10.1158/2159-8290.cd-17-0267
https://doi.org/10.1158/2159-8290.cd-17-0267
Autor:
Livia E. Clarke, C. Le Page, Dale Corkery, Z Xu, Jayme Salsman, Graham Dellaire, A-M Mes-Masson, Liliane Meunier, Brent Johnston, Jason N. Berman, Jordan Pinder, Simon Gebremeskel
Publikováno v:
Oncogene
Anoikis acts as a critical barrier to metastasis by inducing cell death upon cancer cell detachment from the extracellular matrix (ECM), thereby preventing tumor cell dissemination to secondary sites. The induction of anoikis requires the lysosomal-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6879f802bb4d7d23c56c2b8dc3139483
https://doi.org/10.1038/onc.2017.318
https://doi.org/10.1038/onc.2017.318
Autor:
Joyce S. K. Chew, Jordan Pinder, Melanie J. Dobson, Mary E. McQuaid, Niroshaathevi Arumuggam, Jessica S C Lacoste
Publikováno v:
Nucleic Acids Research
The yeast 2-μm plasmid is a remarkable genetic parasite, managing efficient maintenance at high-copy number with minimal impact on the host. Equal partitioning of the plasmid upon host cell division requires plasmid proteins Rep1 and Rep2 and the pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97831308d9b4b945676ab86a2fb553bb
https://doi.org/10.1093/nar/gkx703
https://doi.org/10.1093/nar/gkx703
Autor:
Elliot Drobetsky, Stéphane Richard, Charles Vadnais, Riyan Chen, Tarik Möröy, Jonathan Boulais, Jean-François Côté, Zhenbao Yu, Josée Hébert, Graham Dellaire, Jordan Pinder, Daria Frank, Jennifer Fraszczak, Alexandre Orthwein, Cyrus Khandanpour
Publikováno v:
Cell Stress
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications
GFI1 is a transcriptional regulator expressed in lymphoid cells, and an “oncorequisite” factor required for development and maintenance of T-lymphoid leukemia. GFI1 deletion causes hypersensitivity to ionizing radiation, for which the molecular m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b1a144791a265fcad31ad7eda2b7ea0
https://pubmed.ncbi.nlm.nih.gov/31225488
https://pubmed.ncbi.nlm.nih.gov/31225488