Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Jordan P. Hamm"'
Autor:
Georgia Bastos, Jacob T. Holmes, Jordan M. Ross, Anna M. Rader, Connor G. Gallimore, Joseph A. Wargo, Darcy S. Peterka, Jordan P. Hamm
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113133- (2023)
Summary: Visual stimuli that deviate from the current context elicit augmented responses in the primary visual cortex (V1). These heightened responses, known as “deviance detection,” require local inhibition in the V1 and top-down input from the
Externí odkaz:
https://doaj.org/article/3a1f887a10d04e1799671e7e018b8125
Autor:
Ranjan K. Roy, Ferdinand Althammer, Alexander J. Seymour, Wenting Du, Vinicia C. Biancardi, Jordan P. Hamm, Jessica A. Filosa, Colin H. Brown, Javier E. Stern
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109925- (2021)
Summary: Neurovascular coupling (NVC), the process that links neuronal activity to cerebral blood flow changes, has been mainly studied in superficial brain areas, namely the neocortex. Whether the conventional, rapid, and spatially restricted NVC re
Externí odkaz:
https://doaj.org/article/0f6ae9760d764ee28bc97bde1ff6691a
Autor:
Jordan M. Ross, Jordan P. Hamm
Publikováno v:
Frontiers in Neural Circuits, Vol 14 (2020)
In the neocortex, neuronal processing of sensory events is significantly influenced by context. For instance, responses in sensory cortices are suppressed to repetitive or redundant stimuli, a phenomenon termed “stimulus-specific adaptation” (SSA
Externí odkaz:
https://doaj.org/article/8cad30a8316d45fb999084fac9ec4523
Publikováno v:
Cell Reports, Vol 19, Iss 13, Pp 2681-2693 (2017)
Mapping the fine-scale neural activity that underlies epilepsy is key to identifying potential control targets of this frequently intractable disease. Yet, the detailed in vivo dynamics of seizure progression in cortical microcircuits remain poorly u
Externí odkaz:
https://doaj.org/article/66c3afd298cc4339806039eed9b15c4a
Autor:
Jordan P. Hamm, Rafael Yuste
Publikováno v:
Cell Reports, Vol 16, Iss 3, Pp 597-604 (2016)
Patients with schizophrenia have deficient sensory processing, undermining how they perceive and relate to a changing environment. This impairment can be captured by the reduced mismatch negativity (MMN) index, an electroencephalographic biomarker of
Externí odkaz:
https://doaj.org/article/c2ed229dfecd4a18adc8f91daacb3dab
Publikováno v:
bioRxiv
Context modulates neocortical processing of sensory data. Unexpected visual stimuli elicit large responses in primary visual cortex (V1) -- a phenomenon known as deviance detection (DD) at the neural level, or “mismatch negativity” (MMN) when mea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f1bc26b45cecd763749a513fd3513fa
https://europepmc.org/articles/PMC10153128/
https://europepmc.org/articles/PMC10153128/
Publikováno v:
bioRxiv
A key function of the mammalian neocortex is to process sensory data in the context of current and past stimuli. Primary sensory cortices, such as V1, respond weakly to stimuli that typical in their context but strongly to novel stimuli, an effect kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::796cb354c1f05e8ff250142711464d88
https://europepmc.org/articles/PMC10120723/
https://europepmc.org/articles/PMC10120723/
Autor:
Jordan P. Hamm, Jordan M Ross, Connor G Gallimore, Alice B Van Derveer, Vivien Kubricka, Michelle L Greene, Antanovia D Ferrell, Jacob T Holmes, Georgia Bastos
Publikováno v:
Schizophr Bull
Alterations in neocortical GABAergic interneurons (INs) have been affiliated with neuropsychiatric diseases, including schizophrenia (SZ). Significant progress has been made linking the function of a specific subtype of GABAergic cells, parvalbumin (
Publikováno v:
The Journal of Neuroscience. 39:8562-8575
Understanding seizure formation and spread remains a critical goal of epilepsy research. We used fastin vivotwo-photon calcium imaging in male mouse neocortex to reconstruct, with single-cell resolution, the dynamics of acute (4-aminopyridine) focal