Preclinical evaluation of [225Ac]Ac-DOTA-TATE for treatment of lung neuroendocrine neoplasms

Autor: Narges K. Tafreshi, Haitao Ji, Robert W. Engelman, Jordan N Reff, Zhen Wang, Thaddeus J. Wadas, Alberto Chiappori, Christopher J. Tichacek, David L. Morse, Ghassan El-Haddad, Darpan N. Pandya, Mikalai M. Budzevich, David Boulware, Jonathan R. Strosberg

Publikováno v: European Journal of Nuclear Medicine and Molecular Imaging. 48:3408-3421

There is significant interest in the development of targeted alpha-particle therapies (TATs) for treatment of solid tumors. The metal chelator-peptide conjugate, DOTA-TATE, loaded with the β-particle emitting radionuclide 177Lu ([177Lu]Lu-DOTA-TATE)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6c91d6f8d22fa2108b214d602152c043
https://doi.org/10.1007/s00259-021-05315-1

Preclinical evaluation of [²²⁵Ac]Ac-DOTA-TATE for treatment of lung neuroendocrine neoplasms.

Autor: Tafreshi, Narges K.¹ (AUTHOR), Pandya, Darpan N.² (AUTHOR), Tichacek, Christopher J.^3,4,5 (AUTHOR), Budzevich, Mikalai M.⁶ (AUTHOR), Wang, Zhen⁷ (AUTHOR), Reff, Jordan N.¹ (AUTHOR), Engelman, Robert W.⁸ (AUTHOR), Boulware, David C.⁹ (AUTHOR), Chiappori, Alberto A.¹⁰ (AUTHOR), Strosberg, Jonathan R.¹¹ (AUTHOR), Ji, Haitao⁷ (AUTHOR), Wadas, Thaddeus J.² (AUTHOR), El-Haddad, Ghassan¹² (AUTHOR) Ghassan.ElHaddad@moffitt.org, Morse, David L.^1,4,5,6 (AUTHOR) David.Morse@moffitt.org

Publikováno v: European Journal of Nuclear Medicine & Molecular Imaging. Oct2021, Vol. 48 Issue 11, p3408-3421. 14p. 1 Color Photograph, 1 Diagram, 2 Charts, 6 Graphs.