Distinct molecular phenotypes in male and female schizophrenia patients.

Autor: Jordan M Ramsey, Emanuel Schwarz, Paul C Guest, Nico J M van Beveren, F Markus Leweke, Matthias Rothermundt, Bernhard Bogerts, Johann Steiner, Sabine Bahn

Publikováno v: PLoS ONE, Vol 8, Iss 11, p e78729 (2013)

BACKGROUND: In schizophrenia, sex specific dimorphisms related to age of onset, course of illness and response to antipsychotic treatment may be mirrored by sex-related differences in the underlying molecular pathways. METHODOLOGY/PRINCIPAL FINDINGS:

Externí odkaz: https://doaj.org/article/62e7ee07617c4e26b021937e1c2f8c46

Exploring cellular markers of metabolic syndrome in peripheral blood mononuclear cells across the neuropsychiatric spectrum

Autor: Paula Suárez-Pinilla, Jordan M. Ramsey, Bonnie Auyeug, Volker Arolt, Jantine A. C. Broek, Tillmann Ruland, Marina Rubey, Olya Mikova, Javier Vázquez-Bourgon, Sergi Papiol, Frieder Haenisch, Sabine Bahn, Emiliano Gonzalez-Vioque, Santiago G. Lago, Geertje F. van Rees, Nikolett Kabacs, Jakub Tomasik, Benedicto Crespo-Facorro, Simon Baron-Cohen

Publikováno v: Brain, Behavior, and Immunity. Volume 91, January 2021, Pages 673-682
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
Digital.CSIC. Repositorio Institucional del CSIC
instname

Recent evidence suggests that comorbidities between neuropsychiatric conditions and metabolic syndrome may precede and even exacerbate long-term side-effects of psychiatric medication, such as a higher risk of type 2 diabetes and cardiovascular disea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cddc4ec7faa057300191c4758617894
https://doi.org/10.1016/j.bbi.2020.07.043

Temporal proteomic profiling of postnatal human cortical development

Autor: Avi Ma'ayan, Zichen Wang, Sabine Bahn, Michael S. Breen, Maree J. Webster, Nitin Rustogi, Cynthia Shannon Weickert, Michael G. Gottschalk, Jordan M. Ramsey, Joseph D. Buxbaum, Sureyya Ozcan

Publikováno v: Translational Psychiatry
Translational Psychiatry, Vol 8, Iss 1, Pp 1-14 (2018)

Healthy cortical development depends on precise regulation of transcription and translation. However, the dynamics of how proteins are expressed, function and interact across postnatal human cortical development remain poorly understood. We surveyed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7b5a7626e3faafc99783110fdb72821
http://europepmc.org/articles/PMC6281671

Sex Differences in Serum Markers of Major Depressive Disorder in the Netherlands Study of Depression and Anxiety (NESDA)

Autor: Brenda W.J.H. Penninx, Sabine Bahn, Cynthia Shannon Weickert, Femke Lamers, Paul C. Guest, Jordan M. Ramsey, Mariska Bot, Jason D. Cooper

Publikováno v: PLoS ONE, Vol 11, Iss 5, p e0156624 (2016)
PLoS One (print), 11(5). Public Library of Science
PLoS ONE, 11(5). Public Library of Science
Ramsey, J M, Cooper, J D, Bot, M, Guest, P C, Lamers, F, Weickert, C S, Penninx, B W J H & Bahn, S 2016, ' Sex Differences in Serum Markers of Major Depressive Disorder in the Netherlands Study of Depression and Anxiety (NESDA) ', PLoS ONE, vol. 11, no. 5 . https://doi.org/10.1371/journal.pone.0156624
PLoS ONE

Women have a consistently higher prevalence of major depressive disorder (MDD) than men. Hypotheses implicating hypothalamic-pituitary -adrenal, -gonadal, and -thyroid axes, immune response, genetic factors, and neurotransmitters have emerged to expl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d255181f651165c9e685f19b768764b
http://europepmc.org/articles/PMC4883748?pdf=render

Serum proteomic analysis identifies sex-specific differences in lipid metabolism and inflammation profiles in adults diagnosed with Asperger syndrome

Autor: Bonnie Auyeung, Paul C. Guest, Hannah Steeb, Jordan M. Ramsey, Simon Baron-Cohen, Pawel Stocki, Liliana Ruta, Jason D. Cooper, Sabine Bahn, Erin Ingudomnukul, Hassan Rahmoune

Publikováno v: Molecular Autism
Steeb, H, Ramsey, J M, Guest, P C, Stocki, P, Cooper, J D, Rahmoune, H, Ingudomnukul, E, Auyeung, B, Ruta, L, Baron-Cohen, S & Bahn, S 2014, ' Serum proteomic analysis identifies sex-specific differences in lipid metabolism and inflammation profiles in adults diagnosed with Asperger syndrome ', Molecular Autism, vol. 5, no. 4 . https://doi.org/10.1186/2040-2392-5-4
Molecular Autism, 5. BioMed Central Ltd.

BackgroundThe higher prevalence of Asperger Syndrome (AS) and other autism spectrum conditions in males has been known for many years. However, recent multiplex immunoassay profiling studies have shown that males and females with AS have distinct pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8efeb7e700b747e42af7398ee2267249
https://doi.org/10.1186/2040-2392-5-4