Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jordan M Klaiman"'
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24464 (2011)
Rainbow trout remain active in waters that seasonally change between 4°C and 20°C. To explore how these fish are able to maintain cardiac function over this temperature range we characterized changes in cardiac morphology, contractile function, and
Externí odkaz:
https://doaj.org/article/ea4b605667be46628982e703d78970c6
Autor:
Ketaki N Mhatre, Julie Mathieu, Amy Martinson, Galina Flint, Leslie P. Blakley, Arash Tabesh, Hans Reinecke, Xiulan Yang, Xuan Guan, Eesha Murali, Jordan M Klaiman, Guy L Odom, Mary Beth Brown, Rong Tian, Stephen D Hauschka, Daniel Raftery, Farid Moussavi-Harami, Michael Regnier, Charles E Murry
Transplanted human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) improve ventricular performance when delivered acutely post-myocardial infarction but are ineffective in chronic myocardial infarction/heart failure. 2’-deoxy-ATP (dATP) act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e665b470ba9e0494d5530ab7fecca44b
https://doi.org/10.1101/2023.04.24.538108
https://doi.org/10.1101/2023.04.24.538108
Autor:
Niclas E. Bengtsson, Julie M. Crudele, Jordan M. Klaiman, Christine L. Halbert, Stephen D. Hauschka, Jeffrey S. Chamberlain
Publikováno v:
Mol Ther
Gene editing has shown promise for correcting or bypassing dystrophin mutations in Duchenne muscular dystrophy (DMD). However, preclinical studies have focused on young animals with limited muscle fibrosis and wasting, thereby favoring muscle transdu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f33fd42d19d0dd0ec239a07eb87d1d4
https://europepmc.org/articles/PMC9171147/
https://europepmc.org/articles/PMC9171147/
Autor:
Corrado Poggesi, Chiara Tesi, Alice Ward Racca, Michael R. Hoopmann, Cecilia Ferrantini, J. Manuel Pioner, Lil Pabon, Jordan M. Klaiman, Veronica Muskheli, Michael Regnier, Xuan Guan, Martin K. Childers, Deok Ho Kim, David L. Mack, Charles E. Murry, Robert L. Moritz, Jesse Macadangdang
Publikováno v:
Cardiovasc Res
Aims Heart failure invariably affects patients with various forms of muscular dystrophy (MD), but the onset and molecular sequelae of altered structure and function resulting from full-length dystrophin (Dp427) deficiency in MD heart tissue are poorl
Autor:
Jason S. Huber, Andrew J. Foster, Jordan M. Klaiman, Jeremy A. Simpson, Mathew J. Platt, Todd E. Gillis, Melissa Y Corso
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 310:H572-H586
Dyspnea and reduced exercise capacity, caused, in part, by respiratory muscle dysfunction, are common symptoms in patients with heart failure (HF). However, the etiology of diaphragmatic dysfunction has not been identified. To investigate the effects
Autor:
J. Manuel Pioner, Michael J. Bamshad, Anita E. Beck, Alice Ward Racca, Farid Moussavi-Harami, Yuanhua Cheng, Michael Regnier, Jordan M. Klaiman
Publikováno v:
The Journal of Physiology. 594:437-452
The contractile properties of human fetal cardiac muscle have not yet been described and functional information has been primarily obtained via studies in vivo with echocardiography. Most of what is known about the contractile properties of developin
Autor:
Jordan M. Klaiman, Martin K. Childers
Publikováno v:
Muscle & Nerve. 55:777-779
Autor:
Bradley P Morgan, Eva R. Chin, Martin K. Childers, SiWei Luo, Darren Hwee, Robert W. Grange, David L. Mack, Fady I. Malik, Jordan M. Klaiman
Publikováno v:
Neuromuscular Disorders. 30:S168
Autor:
Farid Moussavi-Harami, Maria V. Razumova, Jordan M. Klaiman, Yuanhua Cheng, Michael Regnier, Jil C. Tardiff
Publikováno v:
Circulation Research. 123
Several studies have identified reduced tension and Ca 2+ sensitivity as key regulators that precipitate dilated cardiomyopathy (DCM). We are developing a novel therapy to increase tension using adeno-associated viral (AAV) vectors that increase intr
Autor:
Farid Moussavi-Harami, Maria V Razumova, Jordan M Klaiman, Darrian Bugg, Michael Regnier, Jennifer Davis
Publikováno v:
Circulation Research. 121
Heart failure with preserved ejection fraction (HFpEF) accounts for at least half of the patients with heart failure, but to date there are no proven therapies for these patients. Cardiac fibrosis and increased collagen content plays an important rol