Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Jordan L Smith"'
Autor:
Alison M Thompson, Jordan L Smith, Luke D Monroe, Jason E Kreutz, Thomas Schneider, Bryant S Fujimoto, Daniel T Chiu, Jerald P Radich, Amy L Paguirigan
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196801 (2018)
Cancer is a heterogeneous disease, and patient-level genetic assessments can guide therapy choice and impact prognosis. However, little is known about the impact of genetic variability within a tumor, intratumoral heterogeneity (ITH), on disease prog
Externí odkaz:
https://doaj.org/article/ff31e625eb914d559a7bbb87f0ea1654
Autor:
Joseph Carver, Thomas S Dexheimer, Dennis Hsu, Meng-Tzu Weng, Jordan L Smith, Rajarshi Guha, Ajit Jadhav, Anton Simeonov, Ji Luo
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103836 (2014)
Mutations in the Ras family of small GTPases, particularly KRAS, occur at high frequencies in cancer and represent a major unmet therapeutic need due to the lack of effective targeted therapies. Past efforts directed at inhibiting the activity of the
Externí odkaz:
https://doaj.org/article/fa1c144e0dc34bbdaa7d17b1fac6ae50
Autor:
David S. Margolis, Gerardo Figueroa, Efren Barron Villalobos, Jordan L. Smith, Cynthia J. Doane, David A. Gonzales, John A. Szivek
Publikováno v:
Journal of Investigative Surgery, Vol 35, Iss 6, Pp 1287-1295 (2022)
Background:There are numerous animal models available to study bone healing as well as test strategies to accelerate bone formation. Sheep are commonly used for evaluation of long bone fractures due to similar dimensions and weight bearing environmen
Externí odkaz:
https://doaj.org/article/8c47ed76604248d59c141e15f264ad28
Autor:
Shun-Qing Liang, Pengpeng Liu, Jordan L. Smith, Esther Mintzer, Stacy Maitland, Xiaolong Dong, Qiyuan Yang, Jonathan Lee, Cole M. Haynes, Lihua Julie Zhu, Jonathan K. Watts, Erik J. Sontheimer, Scot A. Wolfe, Wen Xue
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Nature Communications
Nature Communications
Analysis of off-target editing is an important aspect of the development of safe nuclease-based genome editing therapeutics. in vivo assessment of nuclease off-target activity has primarily been indirect (based on discovery in vitro, in cells or via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ee6a2b871f4a77e574b804ab68c43f5
https://doaj.org/article/102ac89073204ae399bf4e3bc3f7fb8c
https://doaj.org/article/102ac89073204ae399bf4e3bc3f7fb8c
Autor:
Yu, Bing, Swatkoski, Stephen, Holly, Alesia, Lee, Liam C., Giroux, Valentin, Lee, Chih-Shia, Hsu, Dennis, Jordan, L. Smith, Yuen, Garmen, Yue, Junqiu, Ann, David K., Simpson, R. Mark, Creighton, Chad J., Figg, William D., Gucek, Marjan, Luo, Ji
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2015 Apr 01. 112(14), E1724-E1733.
Externí odkaz:
https://www.jstor.org/stable/26462525
Multiomics characterization of mouse hepatoblastoma identifies yes-associated protein 1 target genes
Autor:
Tomás C. Rodríguez, Suet‐Yan Kwan, Jordan L. Smith, Sina Dadafarin, Chern‐Horng Wu, Erik J. Sontheimer, Wen Xue
Publikováno v:
Hepatology (Baltimore, Md.)REFERENCES.
Hepatoblastoma (HB) is the most common primary liver malignancy in childhood and lacks targeted therapeutic options. We previously engineered, to our knowledge, the first yes-associated protein 1 (YAP1)Using a multiomics approach, we integrated high-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afa18370ab9ef39f7a1cae9104781998
https://pubmed.ncbi.nlm.nih.gov/35932276
https://pubmed.ncbi.nlm.nih.gov/35932276
Autor:
Jordan L. Smith, Peter Cruz‐Gordillo, Gabrielle Luiselli, Rrita Daci, Brittany Owusu‐Adjei, Charles Ogagan, Ziev B. Moses
Publikováno v:
Clinical Case Reports
Clinical Case Reports, Vol 10, Iss 1, Pp n/a-n/a (2022)
Clinical Case Reports, Vol 10, Iss 1, Pp n/a-n/a (2022)
Previously viewed as a culture contaminant, Propionibacterium Acnes can cause infection following neurosurgical intervention. Its role in brain abscess in the immunocompetent, surgically naïve population has been infrequently reported. Herein, we de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::840672a87c8112ec1a1306e820526063
http://europepmc.org/articles/PMC8787723
http://europepmc.org/articles/PMC8787723
Autor:
Rui Han, Jingyu Shen, Jingang Wang, Yuling Qin, Li Wu, Jiasi Wang, Jordan L. Smith, Jerald P. Radich, Amy L. Paguirigan, Shihan Xu, Daniel T. Chiu
Publikováno v:
Anal Chem
The ability to sort and dispense droplets accurately is essential to droplet-based single-cell analysis. Here, we describe a fluorescence-activated single-droplet dispenser (FASD) that is analogous to a conventional fluorescence-activated cell sorter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e05a1c49088bb6c3c82373dd15426e06
https://doi.org/10.1021/acs.analchem.9b01017
https://doi.org/10.1021/acs.analchem.9b01017
Autor:
Henry Pratt, Deniz M. Ozata, Tianxiong Yu, Tomás Rodríguez, Haiwei Mou, Max D. Hazeltine, Xiao-Ou Zhang, Yueying Cao, Wen Xue, Shun-Qing Liang, Zhiping Weng, Qiangzong Yin, Jordan L. Smith, Erik J. Sontheimer, Suet-Yan Kwan
Publikováno v:
Hepatology
Background and aims Despite surgical and chemotherapeutic advances, the 5-year survival rate for stage IV hepatoblastoma (HB), the predominant pediatric liver tumor, remains at 27%. Yes-associated protein 1 (YAP1) and β-catenin co-activation occurs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::570058f0831c135cd44758ba807a12e8
https://pubmed.ncbi.nlm.nih.gov/32452550
https://pubmed.ncbi.nlm.nih.gov/32452550
Publikováno v:
The Journal of Arthroplasty. 33:2556-2559
Pelvic positioning during total hip arthroplasty (THA) affects functional position of the acetabular component. We sought to evaluate whether preoperative pelvic tilt correlated with intraoperative pelvic tilt while positioned on a traction table for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::744dc1be3c95c28097eed741572a39fa
https://doi.org/10.1016/j.arth.2018.03.018
https://doi.org/10.1016/j.arth.2018.03.018