Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jordan L Kohlmeyer"'
Autor:
Jordan L Kohlmeyer, David J Gordon, Munir R Tanas, Varun Monga, Rebecca D Dodd, Dawn E Quelle
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8, p 3018 (2020)
Sarcomas represent one of the most challenging tumor types to treat due to their diverse nature and our incomplete understanding of their underlying biology. Recent work suggests cyclin-dependent kinase (CDK) pathway activation is a powerful driver o
Externí odkaz:
https://doaj.org/article/0964510281f54fceb8d7cc183bcb901c
Autor:
David K. Meyerholz, Mariah R. Leidinger, J. Adam Goeken, Thomas R. Businga, Allison Akers, Sebastian Vizuett, Courtney A. Kaemmer, Jordan L. Kohlmeyer, Rebecca D. Dodd, Dawn E. Quelle
Publikováno v:
BMC Research Notes, Vol 15, Iss 1, Pp 1-7 (2022)
Abstract Objective Inflammation is present in many diseases and identification of immune cell infiltration is a common assessment. CD138 (syndecan-1) is a recommended immunohistochemical marker for human plasmacytes although it is also expressed in v
Externí odkaz:
https://doaj.org/article/e118437788d34416b465bf938783c482
Autor:
Dawn E. Quelle, Munir R. Tanas, Benjamin W. Darbro, Rebecca D. Dodd, Jill M. Weimer, K.D. Zamba, David K. Meyerholz, Mariah R. Leidinger, Jessica C. Sieren, Rajesh Khanna, Vickie Knepper-Adrian, Kendall E. Cornick, Heather J. Major, Allison Moreno Samayoa, Chandra K. Maharjan, Casey Pulliam, Courtney A. Kaemmer, Jordan L. Kohlmeyer
RNA-Seq Gene Expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::920ee80e1af2be68a88f0ab59c9465b2
https://doi.org/10.1158/1078-0432.22475733
https://doi.org/10.1158/1078-0432.22475733
Autor:
Dawn E. Quelle, Munir R. Tanas, Benjamin W. Darbro, Rebecca D. Dodd, Jill M. Weimer, K.D. Zamba, David K. Meyerholz, Mariah R. Leidinger, Jessica C. Sieren, Rajesh Khanna, Vickie Knepper-Adrian, Kendall E. Cornick, Heather J. Major, Allison Moreno Samayoa, Chandra K. Maharjan, Casey Pulliam, Courtney A. Kaemmer, Jordan L. Kohlmeyer
Purpose:Malignant peripheral nerve sheath tumors (MPNST) are deadly sarcomas that lack effective therapies. In most MPNSTs, the retinoblastoma (RB1) tumor suppressor is disabled by hyperactivation of cyclin-dependent kinases (CDK), commonly through l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30dd56d880240716d96cf8ae8c86d42c
https://doi.org/10.1158/1078-0432.c.6529155
https://doi.org/10.1158/1078-0432.c.6529155
Autor:
Dawn E. Quelle, Munir R. Tanas, Benjamin W. Darbro, Rebecca D. Dodd, Jill M. Weimer, K.D. Zamba, David K. Meyerholz, Mariah R. Leidinger, Jessica C. Sieren, Rajesh Khanna, Vickie Knepper-Adrian, Kendall E. Cornick, Heather J. Major, Allison Moreno Samayoa, Chandra K. Maharjan, Casey Pulliam, Courtney A. Kaemmer, Jordan L. Kohlmeyer
Antibody Table
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1847e45ac5123d2616c4dc83595c77c3
https://doi.org/10.1158/1078-0432.22475736.v1
https://doi.org/10.1158/1078-0432.22475736.v1
Autor:
Jordan L. Kohlmeyer, Courtney A. Kaemmer, Shaikamjad Umesalma, Francoise A. Gourronc, Aloysius J. Klingelhutz, Dawn E. Quelle
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10, p 5367 (2021)
Schwann cells are normally quiescent, myelinating glia cells of the peripheral nervous system. Their aberrant proliferation and transformation underlie the development of benign tumors (neurofibromas) as well as deadly malignant peripheral nerve shea
Externí odkaz:
https://doaj.org/article/582c4754469c44869f6172b710e3d3ea
Autor:
Anna C. Reisetter, Sadanandan E. Velu, Jordan L. Kohlmeyer, Mariah R. Leidinger, Georgina K. Ofori-Amanfo, Dawn E. Quelle, Parmanand Ahirwar, Chandni Desai, Khadijeh Jahanseir, Jon Thomason, Patrick Breheny, Karen J. Fritchie, Munir R. Tanas
Publikováno v:
Oncotarget
Additional prognostic and therapeutic biomarkers effective across different histological types of sarcoma are needed. Herein we evaluate expression of TAZ and YAP, the p53-MDM2 axis, and RABL6A, a novel oncoprotein with potential ties to both pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::302e0cefa97f956357d6be1d88a0ed49
https://doi.org/10.18632/oncotarget.27928
https://doi.org/10.18632/oncotarget.27928
Autor:
Varun Monga, Munir R. Tanas, Rebecca D. Dodd, David Gordon, Jordan L. Kohlmeyer, Benjamin W. Darbro, Dawn E. Quelle
Publikováno v:
Oncotarget
Precision medicine relies on a detailed molecular understanding of disease pathogenesis. Here, we consider urgently needed therapeutic options for malignant peripheral nerve sheath tumors (MPNSTs) based on emerging insights into druggable pathway alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c48207e50d160176b6b85b797abf1627
http://europepmc.org/articles/PMC7800773
http://europepmc.org/articles/PMC7800773
Autor:
Jordan L Kohlmeyer, Courtney A Kaemmer, Joshua J Lingo, Ellen Voigt, Mariah R Leidinger, Gavin R McGivney, Amanda Scherer, Stacia L Koppenhafer, David J Gordon, Patrick Breheny, David K Meyerholz, Munir R Tanas, Rebecca D Dodd, Dawn E Quelle
Publikováno v:
Neuro-Oncology Advances. 4
Background Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive sarcomas with complex molecular and genetic alterations. Powerful tumor suppressors CDKN2A and TP53 are commonly disrupted along with NF1, a gene that encodes a negative regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1dd3439e7bae0e9878e42d613ea7129
https://doi.org/10.1093/noajnl/vdac047
https://doi.org/10.1093/noajnl/vdac047