Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Jordan L, Meier"'
Autor:
Xuemin Chen, McKenna C. Crawford, Ying Xiong, Anver Basha Shaik, Kiall F. Suazo, Ludwig G. Bauer, Manini S. Penikalapati, Joycelyn H. Williams, Kilian V. M. Huber, Thorkell Andressen, Rolf E. Swenson, Jordan L. Meier
Publikováno v:
JACS Au, Vol 4, Iss 8, Pp 3094-3103 (2024)
Externí odkaz:
https://doaj.org/article/78fefbd568c44de996e8b61d29912560
Autor:
Jayme L. Dahlin, Bruce K. Hua, Beth E. Zucconi, Shawn D. Nelson, Shantanu Singh, Anne E. Carpenter, Jonathan H. Shrimp, Evelyne Lima-Fernandes, Mathias J. Wawer, Lawrence P. W. Chung, Ayushi Agrawal, Mary O’Reilly, Dalia Barsyte-Lovejoy, Magdalena Szewczyk, Fengling Li, Parnian Lak, Matthew Cuellar, Philip A. Cole, Jordan L. Meier, Tim Thomas, Jonathan B. Baell, Peter J. Brown, Michael A. Walters, Paul A. Clemons, Stuart L. Schreiber, Bridget K. Wagner
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Cellular nuisance compounds are a burden in chemical biology and drug screening. Here the authors profile prototypical cytotoxic and nuisance compounds using the cell painting assay to systematically characterise cellular morphologies associated with
Externí odkaz:
https://doaj.org/article/a0652f03d5554808827f7867140b6ae5
Autor:
Alec G. Trub, Gregory R. Wagner, Kristin A. Anderson, Scott B. Crown, Guo-Fang Zhang, J. Will Thompson, Olga R. Ilkayeva, Robert D. Stevens, Paul A. Grimsrud, Rhushikesh A. Kulkarni, Donald S. Backos, Jordan L. Meier, Matthew D. Hirschey
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Statin therapy is associated with numerous cellular effects. Here, the authors show that statin treatment increases post-translational modifications on fatty acid synthase in the active site, revealing communication between the cholesterol and lipid
Externí odkaz:
https://doaj.org/article/6da5de5206424c06a24ccdd0b2b403ff
Autor:
Kellie D. Nance, Jordan L. Meier
Publikováno v:
ACS Central Science, Vol 7, Iss 5, Pp 748-756 (2021)
Externí odkaz:
https://doaj.org/article/70dfffce35364c77ace330865b2a3a3a
Autor:
Isita Jhulki, Jordan L. Meier
Publikováno v:
ACS Central Science, Vol 7, Iss 12, Pp 1963-1965 (2021)
Externí odkaz:
https://doaj.org/article/83511fca3906402f80667067b677582f
Autor:
Mary T. Doan, Michael D. Neinast, Erika L. Varner, Kenneth C. Bedi, Jr., David Bartee, Helen Jiang, Sophie Trefely, Peining Xu, Jay P. Singh, Cholsoon Jang, J. Eduardo Rame, Donita C. Brady, Jordan L. Meier, Kenneth B. Marguiles, Zoltan Arany, Nathaniel W. Snyder
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 6, Pp 100224- (2022)
Anabolic metabolism of carbon in mammals is mediated via the one- and two-carbon carriers S-adenosyl methionine and acetyl-coenzyme A. In contrast, anabolic metabolism of three-carbon units via propionate has not been shown to extensively occur. Mamm
Externí odkaz:
https://doaj.org/article/37582cdc3e554e4a95aee9b775a2c9c9
Autor:
Erika L. Varner, Sophie Trefely, David Bartee, Eliana von Krusenstiern, Luke Izzo, Carmen Bekeova, Roddy S. O'Connor, Erin L. Seifert, Kathryn E. Wellen, Jordan L. Meier, Nathaniel W. Snyder
Publikováno v:
Open Biology, Vol 10, Iss 9 (2020)
Lysine lactoylation is a recently described protein post-translational modification (PTM). However, the biochemical pathways responsible for this acylation remain unclear. Two metabolite-dependent mechanisms have been proposed: enzymatic histone lysi
Externí odkaz:
https://doaj.org/article/adfcecc3a8e9419db3b33858cefd038c
Autor:
Jayme L. Dahlin, Kathryn M. Nelson, Jessica M. Strasser, Dalia Barsyte-Lovejoy, Magdalena M. Szewczyk, Shawna Organ, Matthew Cuellar, Gurpreet Singh, Jonathan H. Shrimp, Nghi Nguyen, Jordan L. Meier, Cheryl H. Arrowsmith, Peter J. Brown, Jonathan B. Baell, Michael A. Walters
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
A substantial obstacle in basic research is the use of poorly validated tool compounds with purported useful biological functions. Here, the authors systematically profile widely used histone acetyltransferase inhibitors and find that the majority ar
Externí odkaz:
https://doaj.org/article/8ca9ff19d5524b75acdb413bf0ff0f30
Autor:
Christian C. Dibble, Samuel A. Barritt, Grace E. Perry, Evan C. Lien, Renee C. Geck, Sarah E. DuBois-Coyne, David Bartee, Thomas T. Zengeya, Emily B. Cohen, Min Yuan, Benjamin D. Hopkins, Jordan L. Meier, John G. Clohessy, John M. Asara, Lewis C. Cantley, Alex Toker
Publikováno v:
Nature. 608:192-198
In response to hormones and growth factors, the class I phosphoinositide-3-kinase (PI3K) signalling network functions as a major regulator of metabolism and growth, governing cellular nutrient uptake, energy generation, reducing cofactor production a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a671b67118b568aca77aca5b34c77ee1
https://doi.org/10.1038/s41586-022-04984-8
https://doi.org/10.1038/s41586-022-04984-8
Autor:
Nathaniel W. Snyder, Jordan L. Meier
Publikováno v:
Nature Chemical Biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c1b84b020f9c5de9dc046977edce56a
https://doi.org/10.1038/s41589-023-01323-4
https://doi.org/10.1038/s41589-023-01323-4