Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jordan Kovacev"'
Autor:
Robert A. Chong, Gary S. Shaw, Zhen-Qiang Pan, Jordan Kovacev, Chan Lee, Kenneth Wu, Jaladhi Nayak, Donald E. Spratt
Publikováno v:
Journal of Biological Chemistry. 289:7068-7081
We have explored the mechanisms of polyubiquitin chain assembly with reconstituted ubiquitination of IκBα and β-catenin by the Skp1-cullin 1-βTrCP F-box protein (SCFβTrCP) E3 ubiquitin (Ub) ligase complex. Competition experiments revealed that S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c3caa6e29221fc20954c2b759f8fb15
https://doi.org/10.1074/jbc.m113.530576
https://doi.org/10.1074/jbc.m113.530576
Autor:
Yongchao Zhao, Yueming Zhu, Douglas R. Spitz, Zhen-Qiang Pan, Jordan Kovacev, Yi Sun, Mingjia Tan
Publikováno v:
Free Radical Biology and Medicine. 49:976-983
SAG (sensitive to apoptosis gene; also known as RBX2 or ROC2) is a dual-function protein with antioxidant activity when acting alone or E3 ligase activity when complexed with other components of SCF (Skp1, cullins, F-box proteins) E3 ubiquitin ligase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9719d54b259803afc09858baa89300e2
https://doi.org/10.1016/j.freeradbiomed.2010.05.030
https://doi.org/10.1016/j.freeradbiomed.2010.05.030
Publikováno v:
Molecular Cell. 37:784-796
We describe a mechanistic model of polyubiquitination by the SCF(beta TrCP2) E3 ubiquitin (Ub) ligase using human I kappaB alpha as a substrate. Biochemical reconstitution experiments revealed that the polyubiquitination of I kappaB alpha began with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6062a27f4e253a452e941e9b921c129b
https://doi.org/10.1016/j.molcel.2010.02.025
https://doi.org/10.1016/j.molcel.2010.02.025
Autor:
I. Elisabeth Johansen, Ole Søgaard Lund, Mette Grønlund, Elodie Piednoir, Jordan Kovacev, Gabriela Didina Constantin
Publikováno v:
Grønlund, M, Constantin, G, Piednoir, E, Kovacev, J, Johansen, I E & Lund, O S 2008, ' Virus-induced gene silencing in Medicago truncatula and Lathyrus odorata ', Virus Research, vol. 135, no. 2, pp. 345-349 . https://doi.org/10.1016/j.virusres.2008.04.005
Virus-induced gene silencing (VIGS) has become an important reverse genetics tool for functional genomics. VIGS vectors based on Pea early browning virus (PEBV, genus Tobravirus) and Bean pod mottle virus (genus Comovirus) are available for the legum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8c830b256889162f845f6a4afded3f5
https://doi.org/10.1016/j.virusres.2008.04.005
https://doi.org/10.1016/j.virusres.2008.04.005
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1280
A key regulatory node in NF-κB signaling is the removal of the IκBα inhibitor, whose levels are tightly controlled by the ubiquitin-proteasome system. In response to signal activation and transmission, ubiquitin E1, E2, and E3 enzymes are employed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d0296daf9e5161618d80895caa11e610
https://pubmed.ncbi.nlm.nih.gov/25736759
https://pubmed.ncbi.nlm.nih.gov/25736759
Publikováno v:
Methods in Molecular Biology ISBN: 9781493924219
A key regulatory node in NF-κB signaling is the removal of the IκBα inhibitor, whose levels are tightly controlled by the ubiquitin-proteasome system. In response to signal activation and transmission, ubiquitin E1, E2, and E3 enzymes are employed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8a91ee4fce4a36d44602ebbd17a1aa6
https://doi.org/10.1007/978-1-4939-2422-6_20
https://doi.org/10.1007/978-1-4939-2422-6_20
Autor:
Jordan, Kovacev, Kenneth, Wu, Donald E, Spratt, Robert A, Chong, Chan, Lee, Jaladhi, Nayak, Gary S, Shaw, Zhen-Qiang, Pan
Publikováno v:
The Journal of biological chemistry. 289(10)
We have explored the mechanisms of polyubiquitin chain assembly with reconstituted ubiquitination of IκBα and β-catenin by the Skp1-cullin 1-βTrCP F-box protein (SCF(βTrCP)) E3 ubiquitin (Ub) ligase complex. Competition experiments revealed that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb8a6ff72eb7dd24538473062f038baf
https://pubmed.ncbi.nlm.nih.gov/24464578
https://pubmed.ncbi.nlm.nih.gov/24464578
Publikováno v:
The FASEB Journal. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0cd6572745f03988ab78e9374687485
https://doi.org/10.1096/fasebj.24.1_supplement.311.3
https://doi.org/10.1096/fasebj.24.1_supplement.311.3