Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jordan J Toutounchian"'
Autor:
Hui He, Rebecca L Weir, Jordan J Toutounchian, Jayaprakash Pagadala, Jena J Steinle, Jerome Baudry, Duane D Miller, Charles R Yates
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0180808 (2017)
Retinal microaneurysms, an early disease manifestation of diabetic retinopathy, are associated with retinal endothelial cell (REC) death and macular edema. We previously demonstrated that a quinic acid (QA) analog, KZ-41, promoted REC survival by blu
Externí odkaz:
https://doaj.org/article/9269fe234af542b5aa18ddc12742acbd
Autor:
Jordan J Toutounchian, Jena J Steinle, Patrudu S Makena, Christopher M Waters, Matthew W Wilson, Barrett G Haik, Duane D Miller, Charles R Yates
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100210 (2014)
Radiation-induced damage to the retina triggers leukostasis, retinal endothelial cell (REC) death, and subsequent hypoxia. Resultant ischemia leads to visual loss and compensatory retinal neovascularization (RNV). Using human RECs, we demonstrated th
Externí odkaz:
https://doaj.org/article/2fa3b981e4d44911a6c66d716e34c0e9
Autor:
Edward Chaum, Jerome Baudry, Frank Park, Charles R. Yates, Jordan J. Toutounchian, Jayaprakash Pagadala, Duane D. Miller
Publikováno v:
Molecular Pharmacology. 91:1-13
Targeting vascular endothelial growth factor (VEGF) is a common treatment strategy for neovascular eye disease, a major cause of vision loss in diabetic retinopathy and age-related macular degeneration. However, the decline in clinical efficacy over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e5920475975e18828a55e9b0e5c7c4f
https://doi.org/10.1124/mol.116.105031
https://doi.org/10.1124/mol.116.105031
Autor:
Charles R. Yates, Jayaprakash Pagadala, Rebecca L. Weir, Jena J. Steinle, Jerome Baudry, Duane D. Miller, Jordan J. Toutounchian, Hui He
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 8, p e0180808 (2017)
PLoS ONE, Vol 12, Iss 8, p e0180808 (2017)
Retinal microaneurysms, an early disease manifestation of diabetic retinopathy, are associated with retinal endothelial cell (REC) death and macular edema. We previously demonstrated that a quinic acid (QA) analog, KZ-41, promoted REC survival by blu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beff2c396d11bda72902dd004d80ae9f
https://pubmed.ncbi.nlm.nih.gov/28796787
https://pubmed.ncbi.nlm.nih.gov/28796787
Publikováno v:
genesis. 55:e23071
Perivascular astrocyte end feet closely juxtapose cerebral blood vessels to regulate important developmental and physiological processes including endothelial cell proliferation and sprouting as well as the formation of the blood-brain barrier (BBB).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f74a5327aa671a3894c12348782c6b06
https://doi.org/10.1002/dvg.23071
https://doi.org/10.1002/dvg.23071
Autor:
Carl Soderland, Karin E. Thompson, Jena J. Steinle, Barrett G. Haik, Matthew W. Wilson, Fan Wang, Timothy D. Mandrell, C. Ryan Yates, Qiuhua Zhang, J. Scott Jackson, Clinton F. Stewart, Dianna A. Johnson, J. Scott Williams, Jordan J. Toutounchian
Purpose. Super-selective intra-ophthalmic artery chemotherapy (SSIOAC) is an eye-targeted drug-delivery strategy to treat retinoblastoma, the most prevalent primary ocular malignancy in children. Unfortunately, recent clinical reports associate adver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::384b36a2d6739fbfc936f337aa45227b
https://europepmc.org/articles/PMC3995559/
https://europepmc.org/articles/PMC3995559/
Autor:
Duane D. Miller, Patrudu S. Makena, Matthew W. Wilson, Christopher M. Waters, Jena J. Steinle, Jordan J. Toutounchian, Barrett G. Haik, Charles R. Yates
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100210 (2014)
PLoS ONE
PLoS ONE
Radiation-induced damage to the retina triggers leukostasis, retinal endothelial cell (REC) death, and subsequent hypoxia. Resultant ischemia leads to visual loss and compensatory retinal neovascularization (RNV). Using human RECs, we demonstrated th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::226d6efce75efe96db2dc5602689fb2a
https://doi.org/10.1371/journal.pone.0100210
https://doi.org/10.1371/journal.pone.0100210
Autor:
Jordan J. Toutounchian, Matthew W. Wilson, Qiuhua Zhang, Duane D. Miller, Vanessa M. Morales-Tirado, Youde Jiang, Jena J. Steinle, C. Ryan Yates
Publikováno v:
Investigative Opthalmology & Visual Science. 54:5937
Purpose To determine whether a novel NF-κB inhibitor, KZ-41, can inhibit melphalan's actions on retinal endothelial cell (REC) inflammation and apoptosis, without eliminating the chemotherapeutic efficacy of melphalan on cell death of retinoblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e950324cde751e62863d4a63c351e444
https://doi.org/10.1167/iovs.13-12326
https://doi.org/10.1167/iovs.13-12326
Autor:
Zhang Q; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, Tennessee, USA., Jiang Y, Toutounchian J, Wilson MW, Morales-Tirado V, Miller DD, Yates CR, Steinle JJ
Publikováno v:
Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2013 Sep 03; Vol. 54 (9), pp. 5937-43. Date of Electronic Publication: 2013 Sep 03.
Autor:
Steinle JJ; Departments of Ophthalmology, Anatomy and Neurobiology, Pharmaceutical Sciences, Radiology, and Comparative Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, USA. jsteinl1@uthsc.edu, Zhang Q, Thompson KE, Toutounchian J, Yates CR, Soderland C, Wang F, Stewart CF, Haik BG, Williams JS, Jackson JS, Mandrell TD, Johnson D, Wilson MW
Publikováno v:
Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2012 Apr 30; Vol. 53 (4), pp. 2439-45. Date of Electronic Publication: 2012 Apr 30.