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Publikováno v:
Biology Direct, Vol 6, Iss 1, p 61 (2011)
Abstract Background Transcription factors are thought to regulate the transcription of microRNA genes in a manner similar to that of protein-coding genes; that is, by binding to conventional transcription factor binding site DNA sequences located in
Externí odkaz:
https://doaj.org/article/7f774a4628a1468a9d25d57f9065625d
Publikováno v:
Mobile DNA, Vol 1, Iss 1, p 2 (2010)
Abstract Background Transposition is disruptive in nature and, thus, it is imperative for host genomes to evolve mechanisms that suppress the activity of transposable elements (TEs). At the same time, transposition also provides diverse sequences tha
Externí odkaz:
https://doaj.org/article/587aa53074b242a7a32ba5a981a5726c
Publikováno v:
BMC Genomics, Vol 9, Iss 1, p 226 (2008)
Abstract Background The majority of human non-protein-coding DNA is made up of repetitive sequences, mainly transposable elements (TEs). It is becoming increasingly apparent that many of these repetitive DNA sequence elements encode gene regulatory f
Externí odkaz:
https://doaj.org/article/786fa36e76514cdaa326abadd401ed4a
Publikováno v:
Biology Direct, Vol 3, Iss 1, p 9 (2008)
Abstract We analyzed the chicken (Gallus gallus) genome sequence to search for previously uncharacterized endogenous retrovirus (ERV) sequences using ab initio and combined evidence approaches. We discovered 11 novel families of ERVs that occupy more
Externí odkaz:
https://doaj.org/article/bfb537f4ce2c48a4a661122f5d97a7db
Publikováno v:
Biology Direct, Vol 2, Iss 1, p 31 (2007)
Abstract Background Transposable element (TE) sequences, once thought to be merely selfish or parasitic members of the genomic community, have been shown to contribute a wide variety of functional sequences to their host genomes. Analysis of complete
Externí odkaz:
https://doaj.org/article/590065c026a947bea067ee56bffb62d7
Autor:
Koonin Eugene V, Bodenreider Olivier, Mariño-Ramírez Leonardo, Tsaparas Panayiotis, Jordan I King
Publikováno v:
BMC Evolutionary Biology, Vol 6, Iss 1, p 70 (2006)
Abstract Background A genome-wide comparative analysis of human and mouse gene expression patterns was performed in order to evaluate the evolutionary divergence of mammalian gene expression. Tissue-specific expression profiles were analyzed for 9,10
Externí odkaz:
https://doaj.org/article/2a7c707ac752412cabe59d24dda85a2b
Autor:
Jordan I King, Mariño-Ramírez Leonardo
Publikováno v:
Biology Direct, Vol 1, Iss 1, p 20 (2006)
Abstract Background Transposable elements (TEs) are abundant genomic sequences that have been found to contribute to genome evolution in unexpected ways. Here, we characterize the evolutionary and functional characteristics of TE-derived human genome
Externí odkaz:
https://doaj.org/article/b3479e1e34d147d28fb8d5b70730562f
Publikováno v:
BMC Evolutionary Biology, Vol 4, Iss 1, p 22 (2004)
Abstract Background Gene duplication is an important mechanism that can lead to the emergence of new functions during evolution. The impact of duplication on the mode of gene evolution has been the subject of several theoretical and empirical compara
Externí odkaz:
https://doaj.org/article/fee2acc4402d48c0b377b3ca648c1a35
Publikováno v:
BMC Evolutionary Biology, Vol 3, Iss 1, p 5 (2003)
Externí odkaz:
https://doaj.org/article/6459de17a7f3449288e114a9b25d57ff