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pro vyhledávání: '"Jordan Grubbs"'
Autor:
Jordan Grubbs, Kareem R. AbdelFattah, Deborah Farr, Sara A. Hennessy, Abier Abdelnaby, Joshua J. Weis, Daniel J. Scott
Publikováno v:
Surgical Endoscopy. 34:4110-4114
In 2014, the ABS introduced the Flexible Endoscopy Curriculum (FEC). The FEC did not alter the minimum defined category case volumes for endoscopy; however, it did introduce specific cognitive and technical milestones for endoscopy training. It also
Smoking Status is Associated with Postoperative Ileus after Colon Resection for Diverticular Disease
Publikováno v:
Journal of the American College of Surgeons. 229:e100-e101
Autor:
Jordan Grubbs, Sergio Huerta
Publikováno v:
International Journal of Surgery Case Reports
Highlights • Jejunal diverticula (JD) are uncommon occurrences that frequently present as a diagnostic dilemma. • Most JD are asymptomatic, only 15% present with surgical problems including perforation. • Perforation from JD is exceedingly rare
Publikováno v:
Biochemistry. 51:2309-2318
Previous osmotic stress studies on the role of solvent in two structurally unrelated dihydrofolate reductases (DHFRs) found weaker binding of dihydrofolate (DHF) to either enzyme in the presence of osmolytes. To explain these unusual results, weak in
Autor:
Michael Jackson, Michael R. Duff, Jordan Grubbs, Chetan Padmashali, Elizabeth E. Howell, Sharghi Rahmanian, Alexa DeLuca
Publikováno v:
Biochemistry. 50:3673-3685
Chromosomal dihydrofolate reductase from Escherichia coli catalyzes the reduction of dihydrofolate to tetrahydrofolate using NADPH as a cofactor. The thermodynamics of ligand binding were examined using an isothermal titration calorimetry approach. U
Autor:
Sumit Goswami, Elizabeth E. Howell, Jian Feng, Ashita Dave, Jordan Grubbs, Caroline Glyn Horner
Publikováno v:
Biochemistry. 49:7384-7392
R67 dihydrofolate reductase (DHFR) is a plasmid-encoded, type II enzyme. Four monomers (78 amino acids long) assemble into a homotetramer possessing 222 symmetry. In previous studies, a tandem array of four R67 DHFR gene copies was fused in frame to
Publikováno v:
Journal of Visualized Experiments : JoVE
Isothermal titration calorimetry (ITC) is a useful tool for understanding the complete thermodynamic picture of a binding reaction. In biological sciences, macromolecular interactions are essential in understanding the machinery of the cell. Experime