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Publikováno v:
The Journal of Experimental Medicine
Regulation of expression of interleukin 7 (IL-7) mRNA is aberrant in the leukemic subset of cells of chronic lymphocytic leukemia (CLL) patients. The entire coding sequence for IL-7 as well as an alternatively spliced IL-7 mRNA are transcribed in the
Autor:
Soo-Hyun Kim, Daniela Novick, Jordan Frishman, Jay Y. Westcott, Charles A. Dinarello, Leonid L. Reznikov, Menachem Rubinstein, Giamila Fantuzzi
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 97(5)
IL-18 shares with IL-1 the same family of receptors and several identical signal transduction pathways. Because of these similarities, IL-18 was investigated for its ability to induce prostaglandin E2(PGE2) synthesis in human peripheral blood mononuc