Glial Cells Missing 1 Regulates Equine Chorionic Gonadotrophin Beta Subunit via Binding to the Proximal Promoter

Autor: Jordan E. Read, Victoria Cabrera-Sharp, Phoebe Kitscha, Judith E. Cartwright, Peter J. King, Robert C. Fowkes, Amanda M. de Mestre

Publikováno v: Frontiers in Endocrinology, Vol 9 (2018)

Equine chorionic gonadotrophin (eCG) is a placental glycoprotein critical for early equine pregnancy and used therapeutically in a number of species to support reproductive activity. The factors in trophoblast that transcriptionally regulate eCGβ-su

Externí odkaz: https://doaj.org/article/e4e561894cde4465b5323be3e103c8ca

Transcriptomic analysis of succinate dehydrogenase subunit deleted cells to identify molecular mechanisms underlying the increased metastatic potential of SDHB-deficient tumours

Autor: Grace Salsbury, Scott A Akker, Charlotte L Hall, Paul Chapple, Jordan E Read, Eugenie Lim

Publikováno v: Endocrine Abstracts.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d41f65ce84e1502e12172e239fcdf083
https://doi.org/10.1530/endoabs.77.oc2.6

Regulation and Function of C-Type Natriuretic Peptide (CNP) in Gonadotrope-Derived Cell Lines

Autor: Samantha M Mirczuk, Andrew J Lessey, Alice R Catterick, Rebecca M Perrett, Christopher J Scudder, Jordan E Read, Victoria J Lipscomb, Stijn J Niessen, Andrew J Childs, Craig A McArdle, Imelda M McGonnell, Robert C Fowkes

Publikováno v: Mirczuk, S M, Lessey, A J, Catterick, A R, Perrett, R M, Scudder, C J, Read, J E, Lipscomb, V J, Niessen, S J, Childs, A J, McArdle, C A, McGonnell, I M & Fowkes, R C 2019, ' Regulation and Function of C-Type Natriuretic Peptide (CNP) in Gonadotrope-Derived Cell Lines ', Cells, vol. 8, no. 9, 1086 . https://doi.org/10.3390/cells8091086
Cells, Vol 8, Iss 9, p 1086 (2019)

C-type natriuretic peptide (CNP) is the most conserved member of the mammalian natriuretic peptide family, and is implicated in the endocrine regulation of growth, metabolism and reproduction. CNP is expressed throughout the body, but is particularly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ec40289ecd61561c030d0cd902af634c
https://research-information.bris.ac.uk/ws/files/244902121/cells_08_01086_v2.pdf

Dynamic changes in gene expression and signalling during trophoblast development in the horse

Autor: Robert C. Fowkes, Victoria Cabrera-Sharp, Jordan E. Read, Amanda M. de Mestre, Samantha M. Mirczuk, Steve Allen, Victoria Offord

Publikováno v: Reproduction (Cambridge, England)

Equine chorionic girdle trophoblast cells play important endocrine and immune functions critical in supporting pregnancy. Very little is known about the genes and pathways that regulate chorionic girdle trophoblast development. Our aim was to identif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9c233102f2f54e34a44533763fc41ef
https://pubmed.ncbi.nlm.nih.gov/29991567

Methotrexate Restores Regulatory T Cell Function Through Demethylation of the FoxP3 Upstream Enhancer in Patients With Rheumatoid Arthritis

Autor: Bernard Gregory, Alan Kennedy, Jordan E. Read, Richard O. Williams, Adam P. Cribbs, Patricia Green, Fionula M. Brennan, Parisa Amjadi, Henry Penn

Publikováno v: Arthritis & Rheumatology. 67:1182-1192

Objective We have previously shown, in a cohort of untreated rheumatoid arthritis (RA) patients, that the suppressive function of Treg cells is defective. However, other studies in cohorts of patients with established RA have shown that Treg cell fun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2f28fb792c7db5bfab8e5c785ce928a0
https://doi.org/10.1002/art.39031