Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jordan D. Irvin"'
Autor:
Jordan D Irvin, Maria L Kireeva, Deanna R Gotte, Brenda K Shafer, Ingold Huang, Mikhail Kashlev, Jeffrey N Strathern
Publikováno v:
PLoS Genetics, Vol 10, Iss 9, p e1004532 (2014)
We developed a highly sensitive assay to detect transcription errors in vivo. The assay is based on suppression of a missense mutation in the active site tyrosine in the Cre recombinase. Because Cre acts as tetramer, background from translation error
Externí odkaz:
https://doaj.org/article/3b7cc81baf9a406c9a61dffbcec2933d
Autor:
Deanna Gotte, Maria L. Kireeva, Lucyna Lubkowska, Jeffrey N. Strathern, Jordan D. Irvin, Francisco Malagon, Brenda Shafer, Mikhail Kashlev, Ding Jun Jin
Publikováno v:
Journal of Biological Chemistry. 288:2689-2699
The fidelity of RNA synthesis depends on both accurate template-mediated nucleotide selection and proper maintenance of register between template and RNA. Loss of register, or transcriptional slippage, is particularly likely on homopolymeric runs in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8a3dde217f1102f686e3d4cc43196ba
https://doi.org/10.1074/jbc.m112.429506
https://doi.org/10.1074/jbc.m112.429506
Autor:
Jordan D. Irvin, Jeffrey N. Strathern, Maria L. Kireeva, Lucyna Lubkowska, Francisco Malagon, Mikhail Kashlev, Yuri A. Nedialkov, Celine Walmacq
Publikováno v:
Journal of Biological Chemistry. 284:19601-19612
Rpb9 is a small non-essential subunit of yeast RNA polymerase II located on the surface on the enzyme. Deletion of the RPB9 gene shows synthetic lethality with the low fidelity rpb1-E1103G mutation localized in the trigger loop, a mobile element of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33e9189bfa47986b355cdaebec993f9d
https://doi.org/10.1074/jbc.m109.006908
https://doi.org/10.1074/jbc.m109.006908
Autor:
B. Franklin Pugh, Jordan D. Irvin
Publikováno v:
Journal of Biological Chemistry. 281:6404-6412
Transcription factor IID (TFIID) plays a central role in regulating the expression of most eukaryotic genes. Of the 14 TBP-associated factor (TAF) subunits that compose TFIID, TAF1 is one of the largest and most functionally diverse. Yeast TAF1 can b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12978d3434966ac80d86a88f382176a4
https://doi.org/10.1074/jbc.m513776200
https://doi.org/10.1074/jbc.m513776200
Publikováno v:
Molecular and Cellular Biology. 23:3186-3201
The TATA binding protein (TBP) is a central component of the eukaryotic transcription machinery and is subjected to both positive and negative regulation. As is evident from structural and functional studies, TBP's concave DNA binding surface is inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea12ade645b6e222d330ee62e20ad37a
https://doi.org/10.1128/mcb.23.9.3186-3201.2003
https://doi.org/10.1128/mcb.23.9.3186-3201.2003
Autor:
Jordan D. Irvin, Carmelata Chitikila, Andrew D. Basehoar, B. Franklin Pugh, Kathryn L. Huisinga
Publikováno v:
Molecular Cell. 10:871-882
The TATA binding protein (TBP) is required for the expression of nearly all genes and is highly regulated both positively and negatively. Here, we use DNA microarrays to explore the genome-wide interplay of several TBP-interacting inhibitors in the y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3293d016fa147a414acf96356e858e1f
https://doi.org/10.1016/s1097-2765(02)00683-4
https://doi.org/10.1016/s1097-2765(02)00683-4
Autor:
Maria L. Kireeva, Brenda Schafer, Ingold Huang, Mikhail Kashlev, Deanna Gotte, Jordan D. Irvin, Jeffrey N. Strathern
Publikováno v:
The FASEB Journal. 28
Transcription errors have been proposed to contribute to tumorigenesis and neurodegenerative diseases. An experimental validation of the biological impact of transcription errors faces major challe...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c863686a7bb44c322d9496d09236e047
https://doi.org/10.1096/fasebj.28.1_supplement.939.2
https://doi.org/10.1096/fasebj.28.1_supplement.939.2
Publikováno v:
Molecular and cellular biology. 31(11)
TATA binding protein (TBP) plays a central role in transcription complex assembly and is regulated by a variety of transcription factors, including Mot1. Mot1 is an essential protein in Saccharomyces cerevisiae that exerts both negative and positive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::588d9596e9055123b9f7ff792164fbcc
https://pubmed.ncbi.nlm.nih.gov/21444714
https://pubmed.ncbi.nlm.nih.gov/21444714
Autor:
Jeffrey N. Strathern, Jordan D. Irvin, Mikhail Kashlev, Maria L. Kireeva, Brenda Shafer, Deanna Gotte, Ingold Huang
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 10, Iss 9, p e1004532 (2014)
PLoS Genetics, Vol 10, Iss 9, p e1004532 (2014)
We developed a highly sensitive assay to detect transcription errors in vivo. The assay is based on suppression of a missense mutation in the active site tyrosine in the Cre recombinase. Because Cre acts as tetramer, background from translation error
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceba587802854cb87757059f065c77e7
https://doi.org/10.1371/journal.pgen.1004532
https://doi.org/10.1371/journal.pgen.1004532