Zobrazeno 1 - 10 of 21 pro vyhledávání: '"Jordan D. Fuqua"'
1
Akademický článek
Impaired proteostatic mechanisms other than decreased protein synthesis limit old skeletal muscle recovery after disuse atrophy
Autor: Jordan D. Fuqua, Marcus M. Lawrence, Zachary R. Hettinger, Agnieszka K. Borowik, Parker L. Brecheen, Marcelina M. Szczygiel, Claire B. Abbott, Frederick F. Peelor III, Amy L. Confides, Michael Kinter, Sue C. Bodine, Esther E. Dupont‐Versteegden, Benjamin F. Miller
Publikováno v: Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 5, Pp 2076-2089 (2023)
Abstract Background Skeletal muscle mass and strength diminish during periods of disuse but recover upon return to weight bearing in healthy adults but are incomplete in old muscle. Efforts to improve muscle recovery in older individuals commonly aim
Externí odkaz: https://doaj.org/article/d851fd486f8f4e6f9a75250858a8e346
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2
Akademický článek
Loss of FoxOs in muscle increases strength and mitochondrial function during aging
Autor: Christie M. Penniman, Gourav Bhardwaj, Colette J. Nowers, Chandler U. Brown, Taylor L. Junck, Cierra K. Boyer, Jayashree Jena, Jordan D. Fuqua, Vitor A. Lira, Brian T. O'Neill
Publikováno v: Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 1, Pp 243-259 (2023)
Abstract Background Muscle mitochondrial decline is associated with aging‐related muscle weakness and insulin resistance. FoxO transcription factors are targets of insulin action and deletion of FoxOs improves mitochondrial function in diabetes. Ho
Externí odkaz: https://doaj.org/article/c9f129a6962c4f9aa5ecf446caaba8e4
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3
Loss of FoxOs in muscle increases strength and mitochondrial function during aging
Autor: Christie M. Penniman, Gourav Bhardwaj, Colette J. Nowers, Chandler U. Brown, Taylor L. Junck, Cierra K. Boyer, Jayashree Jena, Jordan D. Fuqua, Vitor A. Lira, Brian T. O'Neill
Publikováno v: Journal of Cachexia, Sarcopenia and Muscle. 14:243-259
Muscle mitochondrial decline is associated with aging-related muscle weakness and insulin resistance. FoxO transcription factors are targets of insulin action and deletion of FoxOs improves mitochondrial function in diabetes. However, disruptions in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e87a94a920031a61d758783168abcd6f
https://doi.org/10.1002/jcsm.13124
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4
Akademický článek
Preclinical characterization of the JAK/STAT inhibitor SGI-1252 on skeletal muscle function, morphology, and satellite cell content.
Autor: Jacob R Sorensen, Jordan D Fuqua, Michael R Deyhle, Jacob Parmley, Caitlin Skousen, Chad Hancock, Allen C Parcell, Robert D Hyldahl
Publikováno v: PLoS ONE, Vol 13, Iss 6, p e0198611 (2018)
BACKGROUND:Recent studies have highlighted the JAK/STAT signaling pathway in the regulation of muscle satellite cell behavior. Herein we report preclinical studies designed to characterize the effects of a novel JAK/STAT inhibitor on plantar flexor s
Externí odkaz: https://doaj.org/article/24582290f7d64ef2a4f5754b46fdb847
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6
Perinatal versus adult loss of ULK1 and ULK2 distinctly influences cardiac autophagy and function
Autor: Matthew P. Harris, Quan J. Zhang, Cole T. Cochran, Jessica Ponce, Sean Alexander, Ana Kronemberger, Jordan D. Fuqua, Yuan Zhang, Ranan Fattal, Tyler Harper, Matthew L. Murry, Chad E. Grueter, E. Dale Abel, Vitor A. Lira
Impairments in macroautophagy/autophagy, which degrades dysfunctional organelles as well as long-lived and aggregate proteins, are associated with several cardiomyopathies; however, the regulation of cardiac autophagy remains insufficiently understoo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33cb7b7b8865b82c2de78fae87631a13
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8
ADAPTACIONES CARDIOVASCULARES Y DE FUERZA EN EL ENTRENAMIENTO CONCURRENTE EN MUJERES HIPERTENSAS
Autor: Emerson Pardono, Ayrton Moraes Ramos, Gilmar Weber Senna, Estélio Henrique Martin Dantas, Estevão Scudese, Jordan D. Fuqua, Marzo Edir Da Silva-Grigoletto
Publikováno v: Revista Brasileira de Medicina do Esporte v.25 n.5 2019
Revista brasileira de medicina do esporte
Sociedade Brasileira de Medicina do Exercício e do Esporte (SBMEE)
instacron:SBMEE
Revista Brasileira de Medicina do Esporte, Vol 25, Iss 5, Pp 367-371
Revista Brasileira de Medicina do Esporte, Volume: 25, Issue: 5, Pages: 367-371, Published: 07 OCT 2019
Introduction Physical exercise has been recommended as a non-pharmacological strategy for preventing and controlling hypertension. Objective To verify chronic cardiovascular and muscle strength adaptations in hypertensive women who underwent 12 weeks
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::618225e584355a7dfcfc3791da4277a3
https://doi.org/10.1590/1517-869220192505200493
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9
ULK2 is essential for degradation of ubiquitinated protein aggregates and homeostasis in skeletal muscle
Autor: Luís G O de Sousa, Scott M. Ebert, Ana Kronemberger, Ling Yang, Sue C. Bodine, Jay Blomme, Dam Bae, Christopher M. Adams, Matthew P. Harris, Caleb Mere, Jordan D. Fuqua, Mitchell Edwards, Kristen D. Turner, Vitor A. Lira, Estevão Scudese
Publikováno v: The FASEB Journal
Basal protein turnover, which largely relies on the degradation of ubiquitinated substrates, is instrumental for maintenance of muscle mass and function. However, the regulation of ubiquitinated protein degradation in healthy, nonatrophying skeletal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1f5a5a7b28075c59bb042a573948c9c
http://europepmc.org/articles/PMC6902739
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