Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jordan D Lewicky"'
Autor:
Nya L Fraleigh, Reynaldo Oliva, Jordan D Lewicky, Alexandrine L Martel, Reinaldo Acevedo, García-Rivera Dagmar, Hoang-Thanh Le
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0221708 (2019)
Despite the increased risks of cancers and cardiovascular related diseases, tobacco smoking continues to be prevalent in the population due largely in part to the addictive nature of nicotine. Nicotine vaccines are an attractive alternative to the cu
Externí odkaz:
https://doaj.org/article/1983648a0e0846489ba7821c0a2ce9e7
Autor:
Jordan D Lewicky, Alexandrine L Martel, Nya L Fraleigh, Amanda Boraman, Thi M-D Nguyen, Peter W Schiller, Tze Chieh Shiao, René Roy, Hoang-Thanh Le
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0204472 (2018)
The therapeutic application of peptide-based drugs is significantly limited by the rapid proteolytic degradation that occurs when in blood. Encapsulation of these peptide structures within a delivery system, such as liposomes, can greatly improve bot
Externí odkaz:
https://doaj.org/article/84e1b41a2ce54f7cad73c25d5a19d4af
Autor:
Jordan D. Lewicky, Alexandrine L. Martel, Nya L. Fraleigh, Emilie Picard, Leila Mousavifar, Arnaldo Nakamura, Francisco Diaz-Mitoma, René Roy, Hoang-Thanh Le
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2710 (2022)
Perhaps the greatest limitation for the continually advancing developments in cancer immunotherapy remains the immunosuppressive tumor microenvironment (TME). The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) axis is an emergi
Externí odkaz:
https://doaj.org/article/0e88224ddd4740389e6737b8d7385f2e
Autor:
Nya L. Fraleigh, Jordan D. Lewicky, Alexandrine L. Martel, Francisco Diaz-Mitoma, Hoang-Thanh Le
Publikováno v:
Vaccines, Vol 9, Iss 2, p 118 (2021)
Tobacco smoking continues to be a global epidemic and the leading preventable cause of cancer and cardiovascular disease. Nicotine vaccines have been investigated as an alternative to currently available smoking cessation strategies as a means to inc
Externí odkaz:
https://doaj.org/article/19ded2b61e2047dbbf45f99172fcad5e
Autor:
Leila Mousavifar, Jordan D. Lewicky, Alexis Taponard, Rahul Bagul, Madleen Rivat, Shuay Abdullayev, Alexandrine L. Martel, Nya L. Fraleigh, Arnaldo Nakamura, Frédéric J. Veyrier, Hoang-Thanh Le, René Roy
Publikováno v:
Pharmaceutics; Volume 14; Issue 11; Pages: 2300
Glycosylated NPs, including liposomes, are known to target various receptors involved in cellular carbohydrate transport, of which the mannoside binding receptors are attracting particular attention for their expression on various immune cells, cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::714dd78dc56bc5734520f4c42470325b
https://pubmed.ncbi.nlm.nih.gov/36365120
https://pubmed.ncbi.nlm.nih.gov/36365120
Autor:
Anh D. Lê, Alexandrine L. Martel, Leila Mousavifar, Jordan D. Lewicky, Hoang-Thanh Le, Thi M.-D. Nguyen, René Roy, Douglas Funk, Nya L. Fraleigh, Peter W. Schiller
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 15
International Journal of Molecular Sciences, Vol 22, Iss 7996, p 7996 (2021)
Volume 22
Issue 15
International Journal of Molecular Sciences, Vol 22, Iss 7996, p 7996 (2021)
Peptide therapeutics offer numerous advantages in the treatment of diseases and disorders of the central nervous system (CNS). However, they are not without limitations, especially in terms of their pharmacokinetics where their metabolic lability and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c96bed9f96be01a94d61a9d016a901c6
Autor:
Francisco Diaz-Mitoma, Alexandrine L. Martel, Jordan D. Lewicky, Hoang-Thanh Le, Nya L. Fraleigh
Publikováno v:
Vaccines
Volume 9
Issue 2
Vaccines, Vol 9, Iss 118, p 118 (2021)
Volume 9
Issue 2
Vaccines, Vol 9, Iss 118, p 118 (2021)
Tobacco smoking continues to be a global epidemic and the leading preventable cause of cancer and cardiovascular disease. Nicotine vaccines have been investigated as an alternative to currently available smoking cessation strategies as a means to inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::844326bb383af7afe662185a367b5f52
https://pubmed.ncbi.nlm.nih.gov/33546163
https://pubmed.ncbi.nlm.nih.gov/33546163
Autor:
Hoang-Thanh Le, Sarah Fallahi, Nitin Bhardwaj, Paul Dolinar, Sabine Montaut, Justin Boudreau, Francisco Diaz-Mitoma, Jordan D. Lewicky, Nya L. Fraleigh, Alexandrine L. Martel
Publikováno v:
Molecules
Volume 25
Issue 6
Molecules, Vol 25, Iss 6, p 1290 (2020)
Volume 25
Issue 6
Molecules, Vol 25, Iss 6, p 1290 (2020)
The addictive nature of nicotine is likely the most significant reason for the continued prevalence of tobacco smoking despite the widespread reports of its negative health effects. Nicotine vaccines are an alternative to the currently available smok
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d7a194b33223f7f42a90907c5e88122
Autor:
Emilie Picard, Nya L. Fraleigh, Leila Mousavifar, Hoyun Lee, Graham Pawelec, Jordan D. Lewicky, Grace W. Ma, Hoang-Thanh Le, Alexandrine L. Martel, René Roy
Publikováno v:
International Journal of Pharmaceutics. 606:120849
Cancer treatment remains unsatisfactory with high rates of recurrence and metastasis. Immunomodulatory agents capable of promoting cellular antitumor immunity while inhibiting the local immunosuppressive tumor microenvironment could greatly improve c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b95a987f655630ec634c5f523631586
https://doi.org/10.1016/j.ijpharm.2021.120849
https://doi.org/10.1016/j.ijpharm.2021.120849
Autor:
Jordan D. Lewicky, Thi M.-D. Nguyen, Tze Chieh Shiao, Amanda Boraman, René Roy, Peter W. Schiller, Nya L. Fraleigh, Hoang-Thanh Le, Sabine Montaut, Alexandrine L. Martel
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 154
Dynantin is a potent and selective synthetic polypeptide kappa opioid receptor antagonist which has potential antidepressant and anxiolytic-like therapeutic applications, however its clinical development has been hampered by plasma stability issues a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4bcb04819e3e29bb57aa3fa2c4adb2c
https://pubmed.ncbi.nlm.nih.gov/32717389
https://pubmed.ncbi.nlm.nih.gov/32717389