Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jordan C. Evans"'
Autor:
Hunter L. Abrahamsen, Tristan C. Sanford, Casie E. Collamore, Bronte A. Johnstone, Michael J. Coyne, Leonor García-Bayona, Michelle P. Christie, Jordan C. Evans, Allison J. Farrand, Katia Flores, Craig J. Morton, Michael W. Parker, Laurie E. Comstock, Rodney K. Tweten
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Cholesterol-dependent cytolysins (CDCs) comprise a large family of pore-forming toxins produced by Gram-positive bacteria, which are used to attack eukaryotic cells. Here, we functionally characterize a family of 2-component CDC-like (CDCL)
Externí odkaz:
https://doaj.org/article/fa81631103bf486aa966a456bbef1768
Autor:
Jordan C. Evans, Valentina Laclare McEneany, Michael J. Coyne, Elizabeth P. Caldwell, Madeline L. Sheahan, Salena S. Von, Emily M. Coyne, Rodney K. Tweten, Laurie E. Comstock
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The bacterium Phocaeicola vulgatus is commonly found in the human gut. Here, the authors show that the microorganism produces an antibacterial toxin that targets the LPS core glycan of closely related species and induces a response that partially pro
Externí odkaz:
https://doaj.org/article/69744958344440f3b702e995fc9d50c8
Autor:
Jordan C. Evans, Bronte A. Johnstone, Sara L. Lawrence, Craig J. Morton, Michelle P. Christie, Michael W. Parker, Rodney K. Tweten
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
ABSTRACT The cholesterol-dependent cytolysins (CDCs) are bacterial, β-barrel, pore-forming toxins. A central enigma of the pore-forming mechanism is how completion of the prepore is sensed to initiate its conversion to the pore. We identified a moti
Externí odkaz:
https://doaj.org/article/c68956bf53bd4654a2ba9c2e4b08d948
Autor:
Jordan C, Evans, Rodney K, Tweten
Publikováno v:
Methods in enzymology. 649
Pore-forming proteins are found in prokaryotes, vertebrates, and invertebrates, and when involved in pathogenic processes they are classified as pore-forming toxins (PFTs). The use of gene engineering methods in combination with the information provi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::08dea43535eaa0a2693e2ac20856db9a
https://pubmed.ncbi.nlm.nih.gov/33712197
https://pubmed.ncbi.nlm.nih.gov/33712197
Autor:
Rodney K. Tweten, Jordan C Evans
Publikováno v:
Methods in Enzymology ISBN: 9780128238585
Pore-forming proteins are found in prokaryotes, vertebrates, and invertebrates, and when involved in pathogenic processes they are classified as pore-forming toxins (PFTs). The use of gene engineering methods in combination with the information provi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f38acbd9245b8642d966999884f58d57
https://doi.org/10.1016/bs.mie.2021.01.012
https://doi.org/10.1016/bs.mie.2021.01.012
Autor:
Michelle P. Christie, Sara L. Lawrence, Bronte A Johnstone, Michael W. Parker, Rodney K. Tweten, Craig J. Morton, Jordan C Evans
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
mBio
mBio
The cholesterol-dependent cytolysins’ pore-forming mechanism relies on the ability to sense the completion of the oligomeric prepore structure and initiate the insertion of the β-barrel pore from the assembled prepore structure. These studies show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f5e1eece86f90b308a65f02a6fa9802
https://journals.asm.org/doi/10.1128/mBio.02351-20
https://journals.asm.org/doi/10.1128/mBio.02351-20
Autor:
Bronte A. Johnstone, Sara L. Lawrence, Craig J. Morton, Jordan C. Evans, Michelle P. Christie, Rodney K. Tweten, Michael W. Parker
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 77:C482-C482
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aebf7163b44927d1c3e3f00dfd46ea40
https://doi.org/10.1107/s0108767321092047
https://doi.org/10.1107/s0108767321092047