Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jordan Anderson-Daniels"'
Autor:
Samantha L. Grimes, Young J. Choi, Anoosha Banerjee, Gabriel Small, Jordan Anderson-Daniels, Jennifer Gribble, Andrea J. Pruijssers, Maria L. Agostini, Alexandra Abu-Shmais, Xiaotao Lu, Seth A. Darst, Elizabeth Campbell, Mark R. Denison
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT Coronaviruses (CoVs) encode nonstructural proteins 1–16 (nsps 1–16) which form replicase complexes that mediate viral RNA synthesis. Remdesivir (RDV) is an adenosine nucleoside analog antiviral that inhibits CoV RNA synthesis. RDV resist
Externí odkaz:
https://doaj.org/article/351eda1dc8534b2e94fffb7f9053450a
Autor:
Jennifer Gribble, Laura J Stevens, Maria L Agostini, Jordan Anderson-Daniels, James D Chappell, Xiaotao Lu, Andrea J Pruijssers, Andrew L Routh, Mark R Denison
Publikováno v:
PLoS Pathogens, Vol 17, Iss 1, p e1009226 (2021)
Recombination is proposed to be critical for coronavirus (CoV) diversity and emergence of SARS-CoV-2 and other zoonotic CoVs. While RNA recombination is required during normal CoV replication, the mechanisms and determinants of CoV recombination are
Externí odkaz:
https://doaj.org/article/526fcaa34c3442458c7bf131f0326706
Publikováno v:
Journal of virology. 96(16)
Coronaviruses (CoVs) initiate replication by translation of the positive-sense RNA genome into the replicase polyproteins connecting 16 nonstructural protein domains (nsp1-16), which are subsequently processed by viral proteases to yield mature nsp.
Autor:
Jordan Anderson-Daniels, Alan Engelman, Gregory A. Sowd, Christopher Aiken, Parmit K. Singh, Wen Li
Publikováno v:
Journal of virology. 93(21)
Particle maturation is a critical step in the HIV-1 replication cycle that requires proteolytic cleavage of the Gag polyprotein into its constitutive proteins: the matrix (MA), capsid (CA), nucleocapsid (NC), and p6 proteins. The accurate and efficie
Publikováno v:
Journal of Virology
A common feature of infection by positive-sense RNA virus is the modification of host cell cytoplasmic membranes that serve as sites of viral RNA synthesis. Coronaviruses induce double-membrane vesicles (DMVs), but the role of DMVs in replication and