Zobrazeno 1 - 10
of 391
pro vyhledávání: '"Jordan, Lane"'
Autor:
Timo Vögtle, Sumana Sharma, Jun Mori, Zoltan Nagy, Daniela Semeniak, Cyril Scandola, Mitchell J Geer, Christopher W Smith, Jordan Lane, Scott Pollack, Riitta Lassila, Annukka Jouppila, Alastair J Barr, Derek J Ogg, Tina D Howard, Helen J McMiken, Juli Warwicker, Catherine Geh, Rachel Rowlinson, W Mark Abbott, Anita Eckly, Harald Schulze, Gavin J Wright, Alexandra Mazharian, Klaus Fütterer, Sundaresan Rajesh, Michael R Douglas, Yotis A Senis
Publikováno v:
eLife, Vol 8 (2019)
The immunoreceptor tyrosine-based inhibition motif (ITIM)-containing receptor G6b-B is critical for platelet production and activation. Loss of G6b-B results in severe macrothrombocytopenia, myelofibrosis and aberrant platelet function in mice and hu
Externí odkaz:
https://doaj.org/article/c344e049fe504f759f1164a922d96039
Autor:
Johann S. de Bono, Neil Pegg, Karen E. Knudsen, Matthew J. Schiewer, David Taddei, Amanda Swain, Jian Ning, Antje J. Neeb, Suzanne Carreira, Nina Tunariu, Rita Pereira, Ana Ferreira, Mateus Crespo, Susana Miranda, Veronica S. Gil, Gareth W. Harbottle, Don Smyth, Richard Brown, Silvia Paoletta, Jonathan Shannon, Stuart Onions, Jenny Worthington, Stuart Thomson, Jordan Lane, Amy Prosser, Meera Raja, Barbara Young, William West, Denisa Bogdan, Jan Rekowski, Bora Gurel, Ruth Riisnaes, Ines Figueiredo, Abhijit Pal, Saswati N. Chand, Christopher McNair, Wei Yuan, Nigel Brooks, Adam Sharp, Jonathan Welti
Supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d313da933b889d09a6fcaf5a2385ff7
https://doi.org/10.1158/2159-8290.22540441.v1
https://doi.org/10.1158/2159-8290.22540441.v1
Autor:
Dušan Petrović, James S. Scott, Michael S. Bodnarchuk, Olivier Lorthioir, Scott Boyd, George M. Hughes, Jordan Lane, Allan Wu, David Hargreaves, James Robinson, Jens Sadowski
Publikováno v:
Journal of chemical information and modeling. 62(16)
ROS1 rearrangements account for 1-2% of non-small cell lung cancer patients, yet there are no specifically designed, selective ROS1 therapies in the clinic. Previous knowledge of potent ROS1 inhibitors with selectivity over TrkA, a selected antitarge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c3f840f353a4182bae8a31782f88c5
https://pubmed.ncbi.nlm.nih.gov/35920716
https://pubmed.ncbi.nlm.nih.gov/35920716
Autor:
Maya McNealis, John Kent, Kaitlyn Dunlap, Leonard Abbeduto, Anastasia Dimitropoulos, Fred Dombrose, Antonio Hardan, Jordan Lane, Brittani Phillips, Nicki Rodriguez, Dennis P. Wall
Publikováno v:
Journal of the American Academy of Child & Adolescent Psychiatry. 61:S245-S246
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d8584223f53406bb3c47b8c759727c2
https://doi.org/10.1016/j.jaac.2022.09.334
https://doi.org/10.1016/j.jaac.2022.09.334
Autor:
Avipsa Ghosh, Sudhir M. Hande, Amber Balazs, Derek Barratt, Sabina Cosulich, Barry Davies, Sébastien Degorce, Kevin Embrey, Sonja Gill, Anders Gunnarsson, Giuditta Illuzzi, Peter Johnström, Jordan Lane, Carrie Larner, Rachel Lawrence, Elisabetta Leo, Andrew Madin, Elizabeth Martin, Lisa McWilliams, Lenka O’Connor, Mark O’Connor, Jonathan Orme, Fiona Pachl, Martin Packer, Andy Pike, Philip Rawlins, Marianne Schimpl, Magnus Schou, Anna Staniszewska, Wenzhan Yang, James Yates, Andrew Zhang, XiaoLa Zheng, Stephen Fawell, Petra Hamerlik, Jeffrey Johannes
Publikováno v:
Cancer Research. 82:6302-6302
PARP inhibitors exploit defects in DNA repair pathways to selectively target cancerous cells via PARP1 catalytic inhibition and PARP1 trapping onto the DNA. All known clinical PARP1 inhibitors bind at the same site at the catalytic center of the enzy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::288251eb61b3a0254c30186cb54c9b42
https://doi.org/10.1158/1538-7445.am2022-6302
https://doi.org/10.1158/1538-7445.am2022-6302
Autor:
Jordan, Lane, Veronica, Emmerich, Aditi, Senthilnathan, Sree S, Kolli, Leah A, Cardwell, Irma M, Richardson, Steven R, Feldman, Rita O, Pichardo
Publikováno v:
Journal of drugs in dermatology : JDD. 20(10)
Hidradenitis suppurativa patients often seek non-prescription therapies.To determine the prevalence of alternative medicine use and characterize the differences between patients who report using alternative medications versus those who do not.We surv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0447885662d8d3f68c2e1abfa0a9f445
https://pubmed.ncbi.nlm.nih.gov/34636524
https://pubmed.ncbi.nlm.nih.gov/34636524
Autor:
Jeffrey W, Johannes, Amber, Balazs, Derek, Barratt, Michal, Bista, Matthew D, Chuba, Sabina, Cosulich, Susan E, Critchlow, Sébastien L, Degorce, Paolo, Di Fruscia, Scott D, Edmondson, Kevin, Embrey, Stephen, Fawell, Avipsa, Ghosh, Sonja J, Gill, Anders, Gunnarsson, Sudhir M, Hande, Tom D, Heightman, Paul, Hemsley, Giuditta, Illuzzi, Jordan, Lane, Carrie, Larner, Elisabetta, Leo, Lina, Liu, Andrew, Madin, Scott, Martin, Lisa, McWilliams, Mark J, O'Connor, Jonathan P, Orme, Fiona, Pachl, Martin J, Packer, Xiaohui, Pei, Andrew, Pike, Marianne, Schimpl, Hongyao, She, Anna D, Staniszewska, Verity, Talbot, Elizabeth, Underwood, Jeffrey G, Varnes, Lin, Xue, Tieguang, Yao, Ke, Zhang, Andrew X, Zhang, Xiaolan, Zheng
Publikováno v:
Journal of medicinal chemistry. 64(19)
Poly-ADP-ribose-polymerase (PARP) inhibitors have achieved regulatory approval in oncology for homologous recombination repair deficient tumors including BRCA mutation. However, some have failed in combination with first-line chemotherapies, usually
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c3a6bdb821db3eb4c321d1485a73199
https://pubmed.ncbi.nlm.nih.gov/34570508
https://pubmed.ncbi.nlm.nih.gov/34570508
Publikováno v:
Journal of Bronchology & Interventional Pulmonology. 27:216-218
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d60afa4fc3d0836528c61e3fc4b7ee5
https://doi.org/10.1097/lbr.0000000000000680
https://doi.org/10.1097/lbr.0000000000000680
Autor:
Matthew J. Schiewer, Susana Miranda, William West, Suzanne Carreira, Stuart Thomson, Gareth W. Harbottle, Ana Ferreira, Stuart Thomas Onions, Donald Smyth, Nigel Brooks, Jonathan Shannon, Jonathan Welti, Nina Tunariu, Johann S. de Bono, Christopher McNair, Jenny Worthington, Wei Yuan, Karen E. Knudsen, Adam Sharp, Barbara Young, Amy Prosser, Jan Rekowski, Su C, Rita Pereira, Amanda Swain, Jian Ning, Abhijit Pal, Jordan Lane, Ruth Riisnaes, Bora Gurel, Ines Figueiredo, Mateus Crespo, Richard J. C. Brown, Saswati N. Chand, David Michel Adrien Taddei, Denisa Bogdan, Veronica Gil, Silvia Paoletta, Meera Raja, Neil Anthony Pegg, Antje Neeb
Publikováno v:
Cancer discovery. 11(5)
Resistance to androgen receptor (AR) blockade in castration-resistant prostate cancer (CRPC) is associated with sustained AR signaling, including through alternative splicing of AR (AR-SV). Inhibitors of transcriptional coactivators that regulate AR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfbe14e20a3d6b9fa6c1304e667e02ff
https://pubmed.ncbi.nlm.nih.gov/33947717
https://pubmed.ncbi.nlm.nih.gov/33947717
Autor:
Rachel Rowlinson, Alastair J. Barr, Scott Pollack, Juli Warwicker, Jordan Lane, Alexandra Mazharian, Riitta Lassila, Klaus Fütterer, Harald Schulze, Annukka Jouppila, Christopher W Smith, Yotis A. Senis, Mitchell J. Geer, Gavin J. Wright, Jun Mori, Helen J McMiken, Derek Ogg, Daniela Semeniak, Zoltan Nagy, Michael R. Douglas, Cyril Scandola, Timo Vögtle, Anita Eckly, Tina Howard, Sundaresan Rajesh, Catherine Geh, W Mark Abbott, Sumana Sharma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da6d88bbd9eb7d2bcf4e273f3cb396ce
https://doi.org/10.7554/elife.46840.060
https://doi.org/10.7554/elife.46840.060