The TMPRSS2:ERG fusion and response to androgen deprivation therapy for prostate cancer

Autor: Graff RE, Pettersson A, Lis RT, DuPre N, Jordahl KM, Nuttall E, Rider JR, Sesso HD, Kenfield SA, Loda M, Giovannucci EL, Rosner B, Nguyen PL, Sweeney CJ, Mucci LA, Transdisciplinary Prostate Cancer Partnership ToPCaP, FIORENTINO, MICHELANGELO

BACKGROUND: In the United States, half of men with prostate cancer harbor the androgen-regulated gene fusion TMPRSS2:ERG. We hypothesized that men with TMPRSS2:ERG positive tumors are more responsive to androgen deprivation therapy (ADT). METHODS: We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::957ae2bed8ef52d407961ad831654f9c
http://hdl.handle.net/11585/577878

Genetic risk impacts the association of menopausal hormone therapy with colorectal cancer risk.

Autor: Tian Y; School of Public Health, Capital Medical University, Beijing, China.; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Lin Y; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Qu C; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Arndt V; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany., Baurley JW; Bioinformatics and Data Science Research Center, Bina Nusantara University, Jakarta, Indonesia.; BioRealm LLC, Walnut, CA, USA., Berndt SI; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Bien SA; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Bishop DT; Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK., Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Buchanan DD; Colorectal Oncogenomics Group, Department of Clinical Pathology, The University of Melbourne, Parkville, VIC, 3010, Australia.; University of Melbourne Centre for Cancer Research, Victorian Comprehensive Cancer Centre, Parkville, VIC, 3010, Australia.; Genomic Medicine and Family Cancer Clinic, The Royal Melbourne Hospital, Parkville, VIC, Australia., Budiarto A; Bioinformatics and Data Science Research Center, Bina Nusantara University, Jakarta, Indonesia., Campbell PT; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA., Carreras-Torres R; Colorectal Cancer Group, ONCOBELL Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.; Oncology Data Analytics Program, Catalan Institute of Oncology, L'Hospitalet de Llobregat, Barcelona, Spain.; Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain.; Digestive Diseases and Microbiota Group, Girona Biomedical Research Institute Dr Josep Trueta (IDIBGI), Salt, 17190, Girona, Spain., Casey G; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Chan AT; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA., Chen R; School of Public Health, Capital Medical University, Beijing, China., Chen X; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany., Conti DV; Division of Biostatistics, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Díez-Obrero V; Colorectal Cancer Group, ONCOBELL Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.; Oncology Data Analytics Program, Catalan Institute of Oncology, L'Hospitalet de Llobregat, Barcelona, Spain.; Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain., Dimou N; Nutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, France., Drew DA; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Figueiredo JC; Department of Medicine, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Gallinger S; Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada., Giles GG; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia.; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, VIC, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia., Gruber SB; Department of Medical Oncology & Therapeutics Research, City of Hope National Medical Center, Duarte, CA, USA., Gunter MJ; Nutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, France.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Harlid S; Department of Radiation Sciences, Oncology Unit, Umeå University, Umeå, Sweden., Harrison TA; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Hidaka A; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Hoffmeister M; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany., Huyghe JR; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Jenkins MA; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia., Jordahl KM; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA., Joshi AD; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA., Keku TO; Center for Gastrointestinal Biology and Disease, University of North Carolina, Chapel Hill, NC, USA., Kawaguchi E; Division of Biostatistics, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Kim AE; Division of Biostatistics, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Kundaje A; Department of Genetics, Stanford University, Stanford, CA, USA.; Department of Computer Science, Stanford University, Stanford, CA, USA., Larsson SC; Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden., Marchand LL; University of Hawaii Cancer Center, Honolulu, HI, USA., Lewinger JP; Division of Biostatistics, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Li L; Department of Family Medicine, University of Virginia, Charlottesville, VA, USA., Moreno V; Colorectal Cancer Group, ONCOBELL Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.; Oncology Data Analytics Program, Catalan Institute of Oncology, L'Hospitalet de Llobregat, Barcelona, Spain.; Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain.; Department of Clinical Sciences, Faculty of Medicine and health Sciences and Universitat de Barcelona Institute of Complex Systems (UBICS), University of Barcelona (UB), L'Hospitalet de Llobregat, Barcelona, Spain., Morrison J; Division of Biostatistics, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Murphy N; Nutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, France., Nan H; Department of Global Health, Richard M. Fairbanks School of Public Health, Indianapolis, IN, USA.; Department of Epidemiology, Richard M. Fairbanks School of Public Health, Indianapolis, Indianapolis, IN, USA., Nassir R; Department of Pathology, School of Medicine, Umm Al-Qura'a University, Mecca, Saudi Arabia., Newcomb PA; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA., Obón-Santacana M; Colorectal Cancer Group, ONCOBELL Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.; Oncology Data Analytics Program, Catalan Institute of Oncology, L'Hospitalet de Llobregat, Barcelona, Spain.; Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain., Ogino S; Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA.; Program in MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Tokyo Medical and Dental University (Institute of Science Tokyo), Tokyo, Japan., Ose J; Huntsman Cancer Institute, Salt Lake City, UT, USA.; Department of Population Health Sciences, University of Utah, Salt Lake City, UT, USA.; Hochschule Hannover, University of Applied Sciences and Arts, Department III: Media, Information and Design, Hannover, Germany., Pardamean B; Bioinformatics and Data Science Research Center, Bina Nusantara University, Jakarta, Indonesia., Pellatt AJ; Department of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Peoples AR; Huntsman Cancer Institute, Salt Lake City, UT, USA.; Department of Population Health Sciences, University of Utah, Salt Lake City, UT, USA., Platz EA; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Potter JD; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA.; Research Centre for Hauora and Health, Massey University, Wellington, New Zealand., Prentice RL; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Department of Biostatistics, University of Washington, Seattle, WA, USA., Rennert G; Department of Community Medicine and Epidemiology, Lady Davis Carmel Medical Center, Haifa, Israel.; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.; Clalit National Cancer Control Center, Haifa, Israel., Ruiz-Narvaez EA; Department of Nutritional Sciences, University of Michigan School of Public Health, Ann Arbor, MI, USA., Sakoda LC; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA., Schoen RE; Department of Medicine and Epidemiology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Shcherbina A; Biomedical Informatics Program, Department of Biomedical Data Sciences, Stanford University, Stanford, CA, USA., Stern MC; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Su YR; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA., Thibodeau SN; Division of Laboratory Genetics, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA., Thomas DC; Division of Biostatistics, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Tsilidis KK; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece., van Duijnhoven FJB; Division of Human Nutrition and Health, Wageningen University & Research, Wageningen, The Netherlands., Van Guelpen B; Department of Radiation Sciences, Oncology Unit, Umeå University, Umeå, Sweden.; Wallenberg Centre for Molecular Medicine, Umeå University, Umeå, Sweden., Visvanathan K; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., White E; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA., Wolk A; Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden., Woods MO; Memorial University of Newfoundland, Discipline of Genetics, St. John's, NL, Canada., Wu AH; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Peters U; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA., Gauderman WJ; Division of Biostatistics, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Hsu L; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. lih@fredhutch.org.; Department of Biostatistics, University of Washington, Seattle, WA, USA. lih@fredhutch.org., Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany. j.chang-claude@dkfz.de.; University Cancer Centre Hamburg (UCCH), University Medical Centre Hamburg-Eppendorf, Hamburg, Germany. j.chang-claude@dkfz.de.

Publikováno v: British journal of cancer [Br J Cancer] 2024 Jun; Vol. 130 (10), pp. 1687-1696. Date of Electronic Publication: 2024 Apr 01.

Assessing the associations between known genetic variants and substance use in people with HIV in the United States.

Autor: Haas CB; Department of Epidemiology, University of Washington, Seattle, WA, United States of America., Jordahl KM; Department of Epidemiology, University of Washington, Seattle, WA, United States of America., Nance RM; Department of Medicine, University of Washington, Seattle, WA, United States of America., Whitney BM; Department of Medicine, University of Washington, Seattle, WA, United States of America., Wang L; Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, United States of America., Delaney JAC; University of Manitoba, Max Rady College of Medicine, Manitoba, Canada., Ruderman S; Department of Epidemiology, University of Washington, Seattle, WA, United States of America., Jia T; Department of Epidemiology, University of Washington, Seattle, WA, United States of America., Mathews WC; Department of Medicine, University of California at San Diego, San Diego, CA, United States of America., Saag MS; Department of Medicine at the School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States of America., Lee SA; Department of Medicine, University of California at San Francisco, San Francisco, CA, United States of America., Napravnik S; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, United States of America., Jacobson JM; Center for AIDS Research, Case Western Reserve University/University Hospitals Case Medical Center, Cleveland, OH, United States of America., Chander G; Department of Medicine, University of Washington, Seattle, WA, United States of America.; Department of Medicine, Johns Hopkins University, Baltimore, MD, United States of America., McCall EM; Department of Medicine, Johns Hopkins University, Baltimore, MD, United States of America., Moore RD; Department of Medicine, Johns Hopkins University, Baltimore, MD, United States of America., Mayer KH; Harvard Medical School, Beth Israel Deaconess Medical Center, Fenway Health, Boston, MA, United States of America., Mukherjee S; Department of Medicine, University of Washington, Seattle, WA, United States of America., Lee WJ; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America., Crane PK; Department of Medicine, University of Washington, Seattle, WA, United States of America., Crane H; Department of Medicine, University of Washington, Seattle, WA, United States of America., Peter I; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America., Lindström S; Department of Epidemiology, University of Washington, Seattle, WA, United States of America.; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States of America.

Publikováno v: PloS one [PLoS One] 2023 Oct 05; Vol. 18 (10), pp. e0292068. Date of Electronic Publication: 2023 Oct 05 (Print Publication: 2023).

Epigenome-wide meta-analysis of BMI in nine cohorts: Examining the utility of epigenetically predicted BMI.

Autor: Do WL; Laney Graduate School, Emory University, Atlanta, GA, USA., Sun D; Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China; Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA., Meeks K; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA; Department of Public and Occupational Health, Amsterdam Public Health Research Institute, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands., Dugué PA; Precision Medicine, School of Clinical Sciences At Monash Health, Monash University, Clayton, VIC, Australia; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, VIC, Australia; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC 3051, Australia., Demerath E; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA., Guan W; Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN, USA., Li S; Children's Minnesota Research Institute, Childrens Minnesota, Minneapolis, MN, USA., Chen W; Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA., Milne R; Precision Medicine, School of Clinical Sciences At Monash Health, Monash University, Clayton, VIC, Australia; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, VIC, Australia; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC 3051, Australia., Adeyemo A; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Agyemang C; Department of Public and Occupational Health, Amsterdam Public Health Research Institute, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands., Nassir R; Department of Pathology, School of Medicine, Umm Al-Qura University, Mecca, Saudi Arabia., Manson JE; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Shadyab AH; Herbert Wertheim School of Public Health and Human Longevity Science, University of California, San Diego, La Jolla, CA, USA., Hou L; Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Horvath S; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA., Assimes TL; Department of Medicine, School of Medicine, Stanford University, Stanford, CA, USA., Bhatti P; Cancer Control Research, BC Cancer, Vancouver, BC, Canada., Jordahl KM; Department of Epidemiology, University of Washington, Seattle, WA, USA., Baccarelli AA; Department of Environmental Health Sciences, Columbia University, New York, NY, USA., Smith AK; Department of Gynecology and Obstetrics, School of Medicine, Emory University, Atlanta, GA, USA., Staimez LR; Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Stein AD; Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Whitsel EA; Departments of Epidemiology and Medicine, University of North Carolina, Chapel Hill, NC, USA., Narayan KMV; Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Conneely KN; Department of Human Genetics, School of Medicine, Emory University, Atlanta, GA, USA. Electronic address: kconnee@emory.edu.

Publikováno v: American journal of human genetics [Am J Hum Genet] 2023 Feb 02; Vol. 110 (2), pp. 273-283. Date of Electronic Publication: 2023 Jan 16.

Genome-Wide Interaction Analysis of Genetic Variants With Menopausal Hormone Therapy for Colorectal Cancer Risk.

Autor: Tian Y; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; School of Public Health, Capital Medical University, Beijing, China., Kim AE; Division of Biostatistics, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Bien SA; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Lin Y; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Qu C; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Harrison TA; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Carreras-Torres R; Colorectal Cancer Group, ONCOBELL Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.; Oncology Data Analytics Program, Catalan Institute of Oncology, L'Hospitalet de Llobregat, Barcelona, Spain.; Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain., Díez-Obrero V; Colorectal Cancer Group, ONCOBELL Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.; Oncology Data Analytics Program, Catalan Institute of Oncology, L'Hospitalet de Llobregat, Barcelona, Spain.; Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain., Dimou N; Nutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, France., Drew DA; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Hidaka A; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Huyghe JR; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Jordahl KM; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Department of Epidemiology, University of Washington School of Public Health, Seattle, WA, USA., Morrison J; Division of Biostatistics, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Murphy N; Nutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, France., Obón-Santacana M; Colorectal Cancer Group, ONCOBELL Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.; Oncology Data Analytics Program, Catalan Institute of Oncology, L'Hospitalet de Llobregat, Barcelona, Spain.; Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain., Ulrich CM; Huntsman Cancer Institute, Salt Lake City, UT, USA.; Department of Population Health Sciences, University of Utah, Salt Lake City, UT, USA., Ose J; Huntsman Cancer Institute, Salt Lake City, UT, USA.; Department of Population Health Sciences, University of Utah, Salt Lake City, UT, USA., Peoples AR; Huntsman Cancer Institute, Salt Lake City, UT, USA.; Department of Population Health Sciences, University of Utah, Salt Lake City, UT, USA., Ruiz-Narvaez EA; Department of Nutritional Sciences, University of Michigan School of Public Health, Ann Arbor, MI, USA., Shcherbina A; Biomedical Informatics Program, Department of Biomedical Data Sciences, Stanford University, Stanford, CA, USA., Stern MC; Division of Biostatistics, Department of Population and Public Health Sciences & USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Su YR; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA., van Duijnhoven FJB; Division of Human Nutrition and Health, Wageningen University & Research, Wageningen, The Netherlands., Arndt V; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany., Baurley JW; Bioinformatics and Data Science Research Center, Bina Nusantara University, Jakarta, Indonesia.; BioRealm LLC, Walnut, CA, USA., Berndt SI; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Bishop DT; Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK., Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Buchanan DD; Colorectal Oncogenomics Group, Department of Clinical Pathology, The University of Melbourne, Parkville, Victoria, Australia.; University of Melbourne Centre for Cancer Research, Victorian Comprehensive Cancer Centre, Parkville, Victoria, Australia.; Genomic Medicine and Family Cancer Clinic, The Royal Melbourne Hospital, Parkville, Victoria, Australia., Chan AT; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA., Figueiredo JC; Department of Medicine, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Gallinger S; Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada., Gruber SB; Division of Biostatistics, Department of Population and Public Health Sciences & USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Harlid S; Department of Radiation Sciences, Oncology Unit, Umeå University, Umeå, Sweden., Hoffmeister M; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany., Jenkins MA; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia., Joshi AD; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA., Keku TO; Center for Gastrointestinal Biology and Disease, University of North Carolina, Chapel Hill, NC, USA., Larsson SC; Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden., Le Marchand L; University of Hawaii Cancer Center, Honolulu, HI, USA., Li L; Department of Family Medicine, University of Virginia, Charlottesville, VA, USA., Giles GG; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia., Milne RL; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia., Nan H; Department of Global Health, Richard M. Fairbanks School of Public Health, Indianapolis, IN, USA.; Department of Epidemiology, Richard M. Fairbanks School of Public Health, Indianapolis, IN, USA., Nassir R; Department of Pathology, School of Medicine, Umm Al-Qura'a University, Mecca, Saudi Arabia., Ogino S; Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA.; Program in MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Oncologic Pathology, Dana-Farber Cancer Institute, Boston, MA, USA., Budiarto A; Bioinformatics and Data Science Research Center, Bina Nusantara University, Jakarta, Indonesia., Platz EA; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Potter JD; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Research Centre for Hauora and Health, Massey University, Wellington, New Zealand., Prentice RL; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Department of Biostatistics, University of Washington, Seattle, WA, USA., Rennert G; Department of Community Medicine and Epidemiology, Lady Davis Carmel Medical Center, Haifa, Israel.; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.; Clalit National Cancer Control Center, Haifa, Israel., Sakoda LC; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA., Schoen RE; Department of Medicine and Epidemiology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Slattery ML; Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA., Thibodeau SN; Division of Laboratory Genetics, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA., Van Guelpen B; Department of Radiation Sciences, Oncology Unit, Umeå University, Umeå, Sweden.; Wallenberg Centre for Molecular Medicine, Umeå University, Umeå, Sweden., Visvanathan K; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., White E; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Department of Epidemiology, University of Washington School of Public Health, Seattle, WA, USA., Wolk A; Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden., Woods MO; Memorial University of Newfoundland, Discipline of Genetics, St. John's, NL,Canada., Wu AH; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Campbell PT; Department of Population Science, American Cancer Society, Atlanta, GA, USA., Casey G; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Conti DV; Division of Biostatistics, Department of Population and Public Health Sciences & USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Gunter MJ; Nutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, France., Kundaje A; Department of Genetics, Stanford University, Stanford, CA, USA.; Department of Computer Science, Stanford University, Stanford, CA, USA., Lewinger JP; Division of Biostatistics, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Moreno V; Colorectal Cancer Group, ONCOBELL Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.; Oncology Data Analytics Program, Catalan Institute of Oncology, L'Hospitalet de Llobregat, Barcelona, Spain.; Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain.; Department of Clinical Sciences, Faculty of Medicine, University of Barcelona, Barcelona, Spain., Newcomb PA; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Department of Epidemiology, University of Washington School of Public Health, Seattle, WA, USA., Pardamean B; Bioinformatics and Data Science Research Center, Bina Nusantara University, Jakarta, Indonesia., Thomas DC; Division of Biostatistics, Department of Population and Public Health Sciences & USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Tsilidis KK; Department of Epidemiology and Biostatistics, Imperial College London, School of Public Health, London, UK.; 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Publikováno v: Journal of the National Cancer Institute [J Natl Cancer Inst] 2022 Aug 08; Vol. 114 (8), pp. 1135-1148.