Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Jord C, Stam"'
Directing HIV-1 for degradation by non-target cells, using bi-specific single-chain llama antibodies
Autor:
Jord C. Stam, Steven de Maat, Dorien de Jong, Mathia Arens, Fenna van Lint, Lavina Gharu, Mark H. van Roosmalen, Rob C. Roovers, Nika M. Strokappe, Ralf Wagner, Alexander Kliche, Hans J. de Haard, Paul M. van Bergen en Henegouwen, Monique Nijhuis, C. Theo Verrips
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract While vaccination against HIV-1 has been so far unsuccessful, recently broadly neutralizing antibodies (bNAbs) against HIV-1 envelope glycoprotein were shown to induce long-term suppression in the absence of antiretroviral therapy in patient
Externí odkaz:
https://doaj.org/article/ffdba455ddae44ce8e6074f6be3806a7
Autor:
Martijn Schenning, Claudia M. van Tiel, Daniëlle van Manen, Jord C. Stam, Barend M. Gadella, Karel W.A. Wirtz, Gerry T. Snoek
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 8, Pp 1555-1564 (2004)
Mouse fibroblast cells overexpressing phosphatidylinositol transfer protein α [PI-TPα; sense PI-TPα (SPIα) cells] show a significantly increased rate of proliferation and an extreme resistance toward ultraviolet- or tumor necrosis factor-α-induc
Externí odkaz:
https://doaj.org/article/7b6a912c48804825be7ccd62a72321a4
Autor:
L Renee Ruhaak, Carolien A M Koeleman, Hae-Won Uh, Jord C Stam, Diana van Heemst, Andrea B Maier, Jeanine J Houwing-Duistermaat, Paul J Hensbergen, P Eline Slagboom, André M Deelder, Manfred Wuhrer
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73082 (2013)
Protein N-glycosylation patterns are known to show vast genetic as well as physiological and pathological variation and represent a large pool of potential biomarkers. Large-scale studies are needed for the identification and validation of biomarkers
Externí odkaz:
https://doaj.org/article/8b0bcfa75e27459b97fd9da91588f83d
Autor:
Sabrina Oliveira, Guus A.M.S. van Dongen, Marijke Stigter-van Walsum, Rob C. Roovers, Jord C. Stam, Willem Mali, Paul J. van Diest, Paul M.P. van Bergen en Henegouwen
Publikováno v:
Molecular Imaging, Vol 11 (2012)
Given that overexpression of the epidermal growth factor receptor (EGFR) is found in many types of human epithelial cancers, noninvasive molecular imaging of this receptor is of great interest. A number of studies have employed monoclonal antibodies
Externí odkaz:
https://doaj.org/article/5d546d7d79a1479da2e24aff6fffe3bf
Publikováno v:
Shock. 37:247-252
Severe sepsis is characterized by rapid development of multiple organ failure associated with high mortality. Bacterial toxin release triggers a sequence of events that activates intracellular pathways to produce inflammatory mediators and nitric oxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f00eb5c31988ba3492cf3b23fc71e0fd
https://doi.org/10.1097/shk.0b013e3182429b38
https://doi.org/10.1097/shk.0b013e3182429b38
Autor:
Paul J. van Diest, Jord C. Stam, Sabrina Oliveira, Marijke Stigter-van Walsum, Willem P.Th.M. Mali, Rob C. Roovers, Paul M.P. van Bergen en Henegouwen, Guus A.M.S. van Dongen
Publikováno v:
Molecular Imaging, 11(1), 33-46. Decker Publishing
Oliveira, S, van Dongen, G A M S, Stigter-van Walsum, M, Roovers, R C, Stam, J C, Mali, W, van Diest, P J & van Bergen en Henegouwen, P M 2012, ' Rapid Visualization of Human Tumor Xenografts through Optical Imaging with a Near-infrared Fluorescent Anti-Epidermal Growth Factor Receptor Nanobody ', Molecular Imaging, vol. 11, no. 1, pp. 33-46 . https://doi.org/10.2310/7290.2011.00025
Molecular Imaging, Vol 11 (2012)
Oliveira, S, van Dongen, G A M S, Stigter-van Walsum, M, Roovers, R C, Stam, J C, Mali, W, van Diest, P J & van Bergen en Henegouwen, P M 2012, ' Rapid Visualization of Human Tumor Xenografts through Optical Imaging with a Near-infrared Fluorescent Anti-Epidermal Growth Factor Receptor Nanobody ', Molecular Imaging, vol. 11, no. 1, pp. 33-46 . https://doi.org/10.2310/7290.2011.00025
Molecular Imaging, Vol 11 (2012)
Given that overexpression of the epidermal growth factor receptor (EGFR) is found in many types of human epithelial cancers, noninvasive molecular imaging of this receptor is of great interest. A number of studies have employed monoclonal antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23a50106682f0884b6e619bc4535ebbb
https://doi.org/10.2310/7290.2011.00025
https://doi.org/10.2310/7290.2011.00025
Autor:
Bram Maassen, Hendrik Adams, Jaap A. Joles, Jord C. Stam, C. Theo Verrips, Branko Braam, Frank Detmers, Walter J. Brummelhuis, Roel Goldschmeding, Mohamed El Khattabi
Publikováno v:
Shock. 34:125-132
Staphylococcus aureus produces the superantigen toxic shock syndrome toxin 1 (TSST-1). When the bacterium invades the human circulation, this toxin can induce life-threatening gram-positive sepsis. Current sepsis treatment does not remove bacterial t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ced8c9188435919264b065d18829386
https://doi.org/10.1097/shk.0b013e3181cdc556
https://doi.org/10.1097/shk.0b013e3181cdc556
Autor:
Arjan J. Groot, Peter Verheesen, Johan T. den Dunnen, Silvère M. van der Maarel, Arie J. Verkleij, Andreas Roussis, Hans De Haard, Rune R. Frants, Jord C. Stam, C. Theo Verrips
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1764:1307-1319
With the completion of the sequence of the human genome, emphasis is now switching to the human proteome. However, the number of proteins is not only larger than mRNAs in the transcriptome, proteins need often to be in complex with other proteins to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::319e982a11490d234d41a3a106a6e2b0
https://doi.org/10.1016/j.bbapap.2006.05.011
https://doi.org/10.1016/j.bbapap.2006.05.011
Autor:
Arie J. Verkleij, Paul M.P. van Bergen en Henegouwen, Henri H. Versteeg, Willie J. C. Geerts, Jord C. Stam
Publikováno v:
Journal of Biological Chemistry. 276:25176-25183
The v-Crk oncogene encodes an adaptor protein containing an SH2 domain and an SH3 domain. v-Crk-transformed fibroblast cells display enhanced tyrosine phosphorylation levels, and the v-Crk protein localizes in focal adhesions, suggesting that transfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03bd7aa93d84c24912fb6f9529e9bcb6
https://doi.org/10.1074/jbc.m009825200
https://doi.org/10.1074/jbc.m009825200
Publikováno v:
American Review of Respiratory Disease. 147:1259-1263
We observed that in bronchoalveolar lavages (BAL) of patients with active sarcoidosis (SARC) a mononuclear cell infiltrate is present that often contains clusters consisting of lymphocytes adhering to a macrophage. In order to investigate what kind o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b388edd8caf26054af123e1976ba218
https://doi.org/10.1164/ajrccm/147.5.1259
https://doi.org/10.1164/ajrccm/147.5.1259